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Characterization of novel microneme adhesive repeats (MAR) in Eimeria tenella

Marugan-Hernandez, V; Fiddy, R; Nurse-Francis, J; Smith, O; Pritchard, L; Tomley, F M


V Marugan-Hernandez

R Fiddy

J Nurse-Francis

O Smith

L Pritchard

F M Tomley


In this study, we evaluated the binding capacity of Type I MAR domains from novel E. tenella MCPs. Variants of the previously described HxT motif were analysed showing that HxT and VxT variants bind, whereas HxS and YxE variants did not. One of these MCP containing a single MAR (EtMCP2) showed an apical localization when expressed as a fusion with the fluorescent reporter mCherry in transgenic populations and a similar pattern of transcripts per zoite during endogenous development in vitro as the well-characterised microneme protein EtMIC2.


Marugan-Hernandez, V., Fiddy, R., Nurse-Francis, J., Smith, O., Pritchard, L., & Tomley, F. M. (2017). Characterization of novel microneme adhesive repeats (MAR) in Eimeria tenella.

Journal Article Type Article
Acceptance Date Oct 5, 2017
Publication Date Oct 17, 2017
Deposit Date Nov 2, 2017
Publicly Available Date Nov 2, 2017
Journal Parasites & Vectors
Peer Reviewed Peer Reviewed
Volume 10
Issue 491
Public URL


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