Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020

Lewis, Nicola S.; Banyard, Ashley C.; Whittard, Elliot; Karibayev, Talgat; Al Kafagi, Thamer; Chvala, Ilya; Byrne, Alex; Meruyert (Akberovna), Saduakassova; King, Jacqueline; Harder, Timm; Grund, Christian; Essen, Steve; Reid, Scott M.; Brouwer, Adam; Zinyakov, Nikolay G.; Tegzhanov, Azimkhan; Irza, Victor; Pohlmann, Anne; Beer, Martin; Fouchier, Ron A. M.; Akhmetzhan (Akievich), Sultanov; Brown, Ian H.

Abstract

Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected maintenance of H5N8, likely in galliform poultry since 2017/18 and both H5N5 and H5N1. All viruses belong to A/H5 clade 2.3.4.4b with closely related HA genes. Heterogeneity in Eurasian H5Nx HPAI emerging variants threatens poultry production, food security and veterinary public health.

Citation

Lewis, N. S., Banyard, A. C., Whittard, E., Karibayev, T., Al Kafagi, T., Chvala, I., …Brown, I. H. (2021). Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020. Emerging Microbes and Infections, 10(1), 148-151. https://doi.org/10.1080/22221751.2021.1872355

• Journal Article Type: Article
• Acceptance Date: Dec 30, 2020
• Online Publication Date: Jan 17, 2021
• Publication Date: Jan 1, 2021
• Deposit Date: Feb 2, 2021
• Publicly Available Date: Feb 2, 2021
• Journal: Emerging Microbes & Infections
• Publisher: Taylor & Francis Open Access
• Peer Reviewed: Peer Reviewed
• Volume: 10
• Issue: 1
• Pages: 148-151
• DOI: https://doi.org/10.1080/22221751.2021.1872355
• Keywords: Immunology; Epidemiology; Microbiology; Drug Discovery; Parasitology; Virology; Infectious Diseases; General Medicine
• Public URL: https://rvc-repository.worktribe.com/output/1443561
• Additional Information: Peer Review Statement: The publishing and review policy for this title is described in its Aims & Scope.; Aim & Scope: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=temi20; Received: 2020-11-06; Revised: 2020-12-10; Accepted: 2020-12-30; Published: 2021-01-17