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All Outputs (150)

Interleukin 10 controls the balance between tolerance, pathogen elimination and immunopathology in birds (2025)
Journal Article
Meunier, D., Corona-Torres, R., Boulton, K., Wu, Z., Ballantyne, M., Glendinning, L., Ahmad, A. A., Borowska, D., Taylor, L., Vervelde, L., del Pozo, J., Vasilogianni, M., Jaramillo-Ortiz, J., Sanchez-Arsuaga, G., Psifidi, A., Tomley, F., Watson, K. A., McGrew, M. J., Stevens, M. P., Blake, D. P., & Hume, D. A. (2025). Interleukin 10 controls the balance between tolerance, pathogen elimination and immunopathology in birds. eLife, https://doi.org/10.7554/elife.106252.1

Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory cytokine IL10 regulates these processes in the in... Read More about Interleukin 10 controls the balance between tolerance, pathogen elimination and immunopathology in birds.

Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure (2025)
Journal Article
Tripathi, A., Jaiswal, A., Kumar, D., Pandit, R., Blake, D., Tomley, F., Joshi, M., Joshi, C., & Dubey, S. (2025). Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure. International Journal of Antimicrobial Agents, 65(3), https://doi.org/10.1016/j.ijantimicag.2025.107452

Background: Global demand for food has driven expansion and intensification of livestock production, particularly in developing nations where antibiotic use is often routine. Waste from poultry production, including manure, is commonly utilized as fe... Read More about Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure.

Antimicrobial resistance in plant endophytes associated with poultry-manure application revealed by selective culture and whole genome sequencing (2024)
Journal Article
Tripathi, A., Jaiswal, A., Kumar, D., Chavda, P., Pandit, R., Joshi, M., Blake, D., Tomley, F., Joshi, C., & Dubey, S. (2024). Antimicrobial resistance in plant endophytes associated with poultry-manure application revealed by selective culture and whole genome sequencing. Journal of Hazardous Materials, 480, https://doi.org/10.1016/j.jhazmat.2024.136166

Poultry manure is widely used as organic fertilizer in agriculture during the cultivation of crops, but the persistent high-level use of antibiotics in poultry production has raised concerns about the selection for reservoirs of antimicrobial resista... Read More about Antimicrobial resistance in plant endophytes associated with poultry-manure application revealed by selective culture and whole genome sequencing.

Multi-omics analysis reveals regime shifts in the gastrointestinal ecosystem in chickens following anticoccidial vaccination and Eimeria tenella challenge (2024)
Journal Article
Liu, P.-Y., Liaw, J., Soutter, F., Ortiz, J. J., Tomley, F. M., Werling, D., Gundogdu, O., Blake, D. P., & Xia, D. (in press). Multi-omics analysis reveals regime shifts in the gastrointestinal ecosystem in chickens following anticoccidial vaccination and Eimeria tenella challenge. mSystems, https://doi.org/10.1128/msystems.00947-24

The financial cost of coccidiosis in Algerian chicken production: a major challenge for the poultry sector (2024)
Journal Article
Rahmani, A., Laloui, H., Kara, R., Dems, M., Cherb, N., Klikha, A., & Blake, D. (2024). The financial cost of coccidiosis in Algerian chicken production: a major challenge for the poultry sector. Avian Pathology, https://doi.org/10.1080/03079457.2024.2336091

Coccidiosis, caused by parasites of the genus Eimeria, is a significant economic burden to the poultry industry. In this study, we conducted a comprehensive analysis to evaluate the financial losses associated with Eimeria infection in chickens in Al... Read More about The financial cost of coccidiosis in Algerian chicken production: a major challenge for the poultry sector.

Antimicrobial residues in meat from chickens in Northeast Vietnam: analytical validation and pilot study for sampling optimisation (2024)
Journal Article
Pelligand, L., Hedges, S., Cheng, L., Seow, K., Thi, T. H., Huong, L. Q., Son, D. T., Thanh, H. P. T., Cheah, Y. C., Wang, Y., Hurtaud-Pessel, D., Conan, A., Fournié, G., Blake, D., & Tomley, F. (2024). Antimicrobial residues in meat from chickens in Northeast Vietnam: analytical validation and pilot study for sampling optimisation. Journal für Verbraucherschutz und Lebensmittelsicherheit, https://doi.org/10.1007/s00003-024-01478-9

Antimicrobials used in chicken farming for therapeutic and/or prophylactic purposes may result in unacceptable levels of edible residues, if withdrawal periods are not respected. To evaluate the risk in Vietnam, we validated an analytical methods to... Read More about Antimicrobial residues in meat from chickens in Northeast Vietnam: analytical validation and pilot study for sampling optimisation.

Chicken caecal enterotypes in indigenous Kadaknath and commercial Cobb chicken lines are associated with Campylobacter abundance and influenced by farming practices (2023)
Journal Article
Hay, M. C., Hinsu, A. T., Koringa, P. G., Pandit, R. J., Liu, P.-Y., Parekh, M. J., Jakhesara, S. J., Dai, X., Crotta, M., Fosso, B., Limon, G., Guitian, J., Tomley, F. M., Xia, D., Psifidi, A., Joshi, C. G., & Blake, D. P. (2023). Chicken caecal enterotypes in indigenous Kadaknath and commercial Cobb chicken lines are associated with Campylobacter abundance and influenced by farming practices. Frontiers in Microbiomes, https://doi.org/10.3389/frmbi.2023.1301609

Exploring the genetic diversity of Eimeria acervulina: A polymerase chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) approach (2023)
Journal Article
Adeyemi, O., Quill, A., Morikone, M., Evans, L., Formoy, C., Idowu, E. T., Akinsanya, B., Jatau, I. D., & Blake, D. P. (2023). Exploring the genetic diversity of Eimeria acervulina: A polymerase chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) approach. Veterinary Parasitology, 322, 110010. https://doi.org/10.1016/j.vetpar.2023.110010

Resistome profiling reveals transmission dynamics of antimicrobial resistance genes from poultry litter to soil and plant (2023)
Journal Article
Tripathi, A., Kumar, D., Chavda, P., Rathore, D., Pandit, R., Blake, D., Tomley, F., Joshi, M., Joshi, C., & Dubey, S. (2023). Resistome profiling reveals transmission dynamics of antimicrobial resistance genes from poultry litter to soil and plant. Environmental Pollution, 327, https://doi.org/10.1016/j.envpol.2023.121517

Poultry farming is a major livelihood in South and Southeast Asian economies where it is undergoing rapid intensification to meet the growing human demand for dietary protein. Intensification of poultry production systems is commonly supported by inc... Read More about Resistome profiling reveals transmission dynamics of antimicrobial resistance genes from poultry litter to soil and plant.

In Vitro Antioxidant, Antimicrobial, Anticoccidial, and Anti-Inflammatory Study of Essential Oils of Oregano, Thyme, and Sage from Epirus, Greece (2022)
Journal Article
Sidiropoulou, E., Marugán-Hernández, V., Skoufos, I., Giannenas, I., Bonos, E., Aguiar-Martins, K., Lazari, D., Papagrigoriou, T., Fotou, K., Grigoriadou, K., Blake, D. P., & Tzora, A. (in press). In Vitro Antioxidant, Antimicrobial, Anticoccidial, and Anti-Inflammatory Study of Essential Oils of Oregano, Thyme, and Sage from Epirus, Greece. Life, 12(11), 1783. https://doi.org/10.3390/life12111783

Antibiotic usage practices and its drivers in commercial chicken production in Bangladesh (2022)
Journal Article
Chowdhury, S., Fournié, G., Blake, D., Henning, J., Conway, P., Hoque, M. A., Ghosh, S., Parveen, S., Biswas, P. K., Akhtar, Z., Islam, K., Islam, M. A., Rashid, M. M., Pelligand, L., Khan, Z. H., Rahman, M., Tomley, F., Debnath, N., & Chowdhury, F. (2022). Antibiotic usage practices and its drivers in commercial chicken production in Bangladesh. PLoS ONE, 17(10), e0276158. https://doi.org/10.1371/journal.pone.0276158

Irrational and inappropriate use of antibiotics in commercial chicken production can contribute to the development of antimicrobial resistance. We aimed to assess antibiotic usage in commercial chicken production in Bangladesh, and identify factors a... Read More about Antibiotic usage practices and its drivers in commercial chicken production in Bangladesh.

Advances in understanding parasite infections of poultry: focus on protozoa and the red mite (2022)
Book Chapter
Blake, D., & Liebhart, D. (2022). Advances in understanding parasite infections of poultry: focus on protozoa and the red mite. . https://doi.org/10.19103/AS.2022.0104.03

A wide range of parasites can infect poultry, including multiple protozoans, cestodes, nematodes, trematodes and arthropods. As the global chicken population undergoes dramatic expansion, production systems are increasingly moving towards drug-free a... Read More about Advances in understanding parasite infections of poultry: focus on protozoa and the red mite.

Differential expression of microRNAs in the caecal content and faeces of broiler chickens experimentally infected with Eimeria (2022)
Journal Article
Williams, J., Blake, D., & Xia, D. (2022). Differential expression of microRNAs in the caecal content and faeces of broiler chickens experimentally infected with Eimeria. Avian Pathology, https://doi.org/10.1080/03079457.2022.2076581

Differential expression of microRNAs in the caecal content and faeces of broiler chickens experimentally infected with Eimeria

A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens (2022)
Journal Article
Soutter, F., Werling, D., Nolan, M., Küster, T., Attree, E., Marugán-Hernández, V., Kim, S., Tomley, F. M., & Blake, D. (2022). A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens. Frontiers in Immunology, 13, Article 809711. https://doi.org/10.3389/fimmu.2022.809711

Cheap, easy-to-produce oral vaccines are needed for control of coccidiosis in chickens to reduce the impact of this disease on welfare and economic performance. Saccharomyces cerevisiae yeast expressing three Eimeria tenella antigens were developed a... Read More about A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens.