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Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019) (2022)
Journal Article
Beeston, D., Jepson, R., & Cortellini, S. (2022). Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019). Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13530

Title: Evaluation of presentation, treatment and outcome in hypertensive emergency in dogs and cats: 15 cases (2003-2019).
Introduction: Hypertensive emergency (HE) is well-recognised in human medicine, yet there is limited veterinary evidence. This... Read More about Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019).

Ionized hypercalcemia in cats with azotemic chronic kidney disease (2012-2018) (2022)
Journal Article
van den Broek, D., Geddes, R., Lotter, N., Chang, Y., Elliott, J., & Jepson, R. (2022). Ionized hypercalcemia in cats with azotemic chronic kidney disease (2012-2018). Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16430

Background Hypercalcemia is associated with chronic kidney disease (CKD) in cats, but studies assessing the physiologically relevant ionized calcium fraction are lacking. Objectives To describe the prevalence and incidence rate of ionized hypercalcem... Read More about Ionized hypercalcemia in cats with azotemic chronic kidney disease (2012-2018).

Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass (2022)
Journal Article
Starybrat, D., Jepson, R., Bristow, P., Peterson, S., Yerramilli, M., Yerramilli, M., Chang, Y.-M., & Cortellini, S. (online). Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass. Journal of Veterinary Emergency and Critical Care, https://doi.org/10.1111/vec.13250

Objective To assess the occurrence of acute kidney injury (AKI) in dogs undergoing cardiac surgery under cardiopulmonary bypass (CPB) and explore associations between traditional and novel serum and urinary biomarkers. Design Prospective cohort study... Read More about Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass.

First Genome-Wide Association Study Investigating Blood Pressure and Renal Traits in Domestic Cats (2022)
Journal Article
Jepson, R. E., Warren, H., Syme, H. M., Elliott, J., & Munroe, P. B. (2022). First Genome-Wide Association Study Investigating Blood Pressure and Renal Traits in Domestic Cats. Scientific Reports, https://doi.org/10.1038/s41598-022-05494-3

Hypertension (HTN) and chronic kidney disease (CKD) are common in ageing cats. In humans, blood pressure (BP) and renal function are complex heritable traits. We performed the first feline Genome-Wide Association Study (GWAS) of quantitative traits s... Read More about First Genome-Wide Association Study Investigating Blood Pressure and Renal Traits in Domestic Cats.

Risk factors and implications associated with renal mineralization in chronic kidney disease in cats (2022)
Journal Article
Tang, P., Jepson, R., Chang, Y., Geddes, R., Hopkinson, M., & Elliott, J. (2022). Risk factors and implications associated with renal mineralization in chronic kidney disease in cats. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16363

Background
Nephrocalcinosis is a pathological feature of chronic kidney disease (CKD). Its pathophysiological implications for cats with CKD are unexplored.

Objectives
Identify nephrocalcinosis risk factors and evaluate its influence on CKD prog... Read More about Risk factors and implications associated with renal mineralization in chronic kidney disease in cats.