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A prospective multicenter observational study assessing incidence and risk factors for acute blood transfusion reactions in dogs (2024)
Journal Article
Hall, G., Birkbeck, R., Brainard, B., Camacho, F., Davidow, E., Levine, D., Mackin, A., Moss, T., Nash, K., Stanzani, G., Starybrat, D., Stoye, D., Tai, C., Thomason, J., Walker, J., Wardrop, K., Wilson, H., Wurlod, V., & Humm, K. (2024). A prospective multicenter observational study assessing incidence and risk factors for acute blood transfusion reactions in dogs. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.17175

BackgroundReported incidence of blood transfusion reactions (TR) varies greatly.ObjectiveTo prospectively evaluate the incidence of acute TRs in dogs receiving allogenic blood products, using consensus definitions, and to assess factors associated wi... Read More about A prospective multicenter observational study assessing incidence and risk factors for acute blood transfusion reactions in dogs.

Placement Management And Complications Associated With Peripheral Intravenous Catheter Use In UK Small Animal Practice (2024)
Journal Article
Scudder, C., Haskey, E., Maund, V., Allerton, F., Browse, B., Heard, C., O'Donnell, C., Davison, K., Hertel, C., Booth, E., Lawrence, S., Dever, E., Taylor, H., Hall, K., Junior, M., Fennell, C., Stevenson, N., Sterritt, A., Penn, E., Nowell, L., …Jones, E. (in press). Placement Management And Complications Associated With Peripheral Intravenous Catheter Use In UK Small Animal Practice. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13782

Objectives: To describe the techniques for preparation and placement of peripheral intravenous catheters (PIVCs), to describe the complications associated with PIVCs, and to identify factors associated with PIVC complications in small animal practice... Read More about Placement Management And Complications Associated With Peripheral Intravenous Catheter Use In UK Small Animal Practice.

Magnetic resonance imaging findings in dogs with steroid-responsive meningitis-arteritis in the UK and their clinical significance: 53 cases (2013-2021) (2024)
Journal Article
Jones, B., Agthe, P., Scarpante, E., Crawford, A., Black, V., Espadas, I., Formoso, S., & Fraser, A. (2024). Magnetic resonance imaging findings in dogs with steroid-responsive meningitis-arteritis in the UK and their clinical significance: 53 cases (2013-2021). Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13775

Objectives: To describe the MRI findings in a UK referral population of dogs with steroid-responsive meningitis-arteritis and to determine if they were associated with any specific clinical features or outcomes. Materials and Methods: We performed a... Read More about Magnetic resonance imaging findings in dogs with steroid-responsive meningitis-arteritis in the UK and their clinical significance: 53 cases (2013-2021).

Progress and Challenges: Implementation of the UK antimicrobial resistance national action plan 2019-2024 within the beef cattle sub-sector (2024)
Journal Article
Bennani, H., Haesler, B., Whatford, L., Myers, J., May, N., & Glover, R. (2024). Progress and Challenges: Implementation of the UK antimicrobial resistance national action plan 2019-2024 within the beef cattle sub-sector. Antibiotics, https://doi.org/10.3390/antibiotics13090839

The five-year UK antimicrobial resistance (AMR) National Action Plan (NAP) was published in 2019 focusing on reducing the need for, and unintentional exposure to antimicrobials (AMs); optimising use of AMs; and investing in innovation, supply and acc... Read More about Progress and Challenges: Implementation of the UK antimicrobial resistance national action plan 2019-2024 within the beef cattle sub-sector.

Understanding the interests of academics from diverse disciplines to identify the prospective focus for a UK-based transdisciplinary network involving farm-to-fork stakeholders on antimicrobial resistance in agrifood systems: An online survey (2024)
Journal Article
McIntyre, K., Khan, M., Betson, M., Brunton, L., Degiovanni, H., Desbois, A., Eltholth, M., Hurley, P., Morgans, L., Pearl, J., Sakrabani, R., Shortall, O., Watson, K., & Cole, J. (2024). Understanding the interests of academics from diverse disciplines to identify the prospective focus for a UK-based transdisciplinary network involving farm-to-fork stakeholders on antimicrobial resistance in agrifood systems: An online survey. One Health, 19, https://doi.org/10.1016/j.onehlt.2024.100884

Antimicrobial resistance (AMR) evolution and onward transmission of resistance genes is impacted by interrelated biological and social drivers, with evidence and impacts observed across human, animal and environmental One Health domains. Systems-base... Read More about Understanding the interests of academics from diverse disciplines to identify the prospective focus for a UK-based transdisciplinary network involving farm-to-fork stakeholders on antimicrobial resistance in agrifood systems: An online survey.

Treatment outcome of spontaneous chronic corneal epithelial defects in brachycephalic dogs comparing Boxers and non-Boxers: A retrospective multicenter study of 420 dogs (2024)
Journal Article
Goncalves, C., Oliver, J., Kafarnik, C., Garnett, K., Rushton, J., Stravinskaite, V., Everson, R., Tee, F., Escribano-Bermejo, B., Tzouganakis, I., Lacerda, R., Pearce, I., & Fricker, G. (2024). Treatment outcome of spontaneous chronic corneal epithelial defects in brachycephalic dogs comparing Boxers and non-Boxers: A retrospective multicenter study of 420 dogs. Veterinary Ophthalmology, https://doi.org/10.1111/vop.13269

Objective: To compare characteristics and treatment outcomes of spontaneous chronic corneal epithelial defects (SCCEDs) in brachycephalic non-Boxers and Boxers. We hypothesized that brachycephalic non-Boxers develop SCCEDs at a younger age and develo... Read More about Treatment outcome of spontaneous chronic corneal epithelial defects in brachycephalic dogs comparing Boxers and non-Boxers: A retrospective multicenter study of 420 dogs.

Computed tomographic findings of a nasal neuroendocrine neoplasm with intracranial extension in a horse (2024)
Journal Article
Giorio, M., Mitchell, J., Priestnall, S., Dunkel, B., Dash, R., & Berner, D. (2024). Computed tomographic findings of a nasal neuroendocrine neoplasm with intracranial extension in a horse. Equine Veterinary Education, https://doi.org/10.1111/eve.14040

A 20-year-old Irish Sport Horse gelding was presented to the Royal Veterinary College Equine Referral Hospital for investigation of left-sided epistaxis, depression and gait abnormalities of approximately 1 month duration. Physical examination and cr... Read More about Computed tomographic findings of a nasal neuroendocrine neoplasm with intracranial extension in a horse.

Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy (2024)
Journal Article
Zhao, W., Shen, T., Zhao, B., Li, M., Deng, Z., Huo, Y., Aernouts, B., Loor, J., Psifidi, A., & Xu, C. (2024). Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy. Journal of Animal Science and Biotechnology, 15(1), https://doi.org/10.1186/s40104-024-01066-9

BackgroundSubacute ruminal acidosis (SARA) causes an increase in endotoxin, which can induce immune and inflammatory responses in the ruminal epithelium of dairy cows. In non-ruminants, epigallocatechin-3-gallate (EGCG), a major bioactive ingredient... Read More about Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.

Comparative muscle anatomy of the anuran pelvis and hindlimb in relation to locomotor mode (2024)
Journal Article
Leavey, A., Richards, C., & Porro, L. (2024). Comparative muscle anatomy of the anuran pelvis and hindlimb in relation to locomotor mode. Journal of Anatomy, https://doi.org/10.1111/joa.14122

Frogs have a highly conserved body plan, yet they employ a diverse array of locomotor modes, making them ideal organisms for investigating the relationships between morphology and locomotor function, in particular whether anatomical complexity is a p... Read More about Comparative muscle anatomy of the anuran pelvis and hindlimb in relation to locomotor mode.

LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensis (2024)
Journal Article
Holmes, G., Ferguson, S., Lewis, P., & Echeverri, K. (2024). LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensis. Neural Development, 19(1), https://doi.org/10.1186/s13064-024-00193-3

Background The starlet sea anemone, Nematostella vectensis, is an emerging model organism with a high regenerative capacity, which was recently found to possess an orthologue to the human Leucine Rich Repeat Kinase 2 (LRRK2) gene. Mutations in this g... Read More about LRRK2 kinase activity is necessary for development and regeneration in Nematostella vectensis.

The functions of leg muscles, structures and mechanisms in running (2024)
Journal Article
Usherwood, J. (2024). The functions of leg muscles, structures and mechanisms in running. Biology Letters, 20(8), https://doi.org/10.1098/rsbl.2024.0260

The actions of the major human leg muscles are well established; however, the functions of these muscle actions during steady running remain unclear. Here, leg structures and mechanisms are considered in terms of their functions in meeting the task o... Read More about The functions of leg muscles, structures and mechanisms in running.

Surgical treatment and outcome of primary rib tumours in cats: eight cases (2016-2023) (2024)
Journal Article
Cinti, F., Martano, M., Rossanese, M., Selmic, L., Fontes, G., Cino, M., Montinaro, V., & Tremolada, G. (2024). Surgical treatment and outcome of primary rib tumours in cats: eight cases (2016-2023). Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13770

ObjectivesTo describe the clinical features and oncologic outcome for cats with primary rib tumours.Materials and MethodsMedical records for cats with surgically treated primary rib tumours from six veterinary referral centres were reviewed. Signalme... Read More about Surgical treatment and outcome of primary rib tumours in cats: eight cases (2016-2023).

Anatomical classification of canine congenital extrahepatic portosystemic shunts based on CT angiography: A SVSTS and VIRIES multi-institutional study in 1082 dogs (2024)
Journal Article
Weisse, C., Fox-Alvarez, W., Grosso, F., Asano, K., Ishigaki, K., Zwingenberger, A., Carroll, K., Scharf, V., Lipscomb, V., Wallace, M., Aly, A., Biscoe, B., Davidson, J., Arai, S., Amato, N., Ryan, S., Woods, S., & An, A. (2024). Anatomical classification of canine congenital extrahepatic portosystemic shunts based on CT angiography: A SVSTS and VIRIES multi-institutional study in 1082 dogs. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13415

Canine congenital extrahepatic portosystemic shunt (EHPSS) morphologies have not been fully elucidated. The goal of this retrospective, multi-institutional study was to use CT angiography to create an anatomical-based nomenclature system for canine c... Read More about Anatomical classification of canine congenital extrahepatic portosystemic shunts based on CT angiography: A SVSTS and VIRIES multi-institutional study in 1082 dogs.

Impact of Lameness on Brush Use in a Loose-Housed Dairy System (2024)
Journal Article
Burton, Y. I., & Blackie, N. (2024). Impact of Lameness on Brush Use in a Loose-Housed Dairy System. Ruminants, 4(3), 375-386. https://doi.org/10.3390/ruminants4030027

This study focused on a group of 49 high-yielding dairy cows (primarily Holstein Friesians) and how their interactions with wall-mounted automated brushes correlated to their mobility (also described as lameness) score (AHDB 0–3 system. Of the 49 ani... Read More about Impact of Lameness on Brush Use in a Loose-Housed Dairy System.

Fetal growth restriction and placental defects in obese mice are associated with impaired decidualisation: the role of increased leptin signalling modulators SOCS3 and PTPN2 (2024)
Journal Article
Walewska, E., Makowczenko, K., Witek, K., Laniecka, E., Molcan, T., Alvarez-Sanchez, A., Kelsey, G., Perez-Garcia, V., & Galvao, A. (2024). Fetal growth restriction and placental defects in obese mice are associated with impaired decidualisation: the role of increased leptin signalling modulators SOCS3 and PTPN2. Cellular and Molecular Life Sciences, 81(1), https://doi.org/10.1007/s00018-024-05336-7

Decidualisation of the endometrium is a key event in early pregnancy, which enables embryo implantation. Importantly, the molecular processes impairing decidualisation in obese mothers are yet to be characterised. We hypothesise that impaired decidua... Read More about Fetal growth restriction and placental defects in obese mice are associated with impaired decidualisation: the role of increased leptin signalling modulators SOCS3 and PTPN2.