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All Outputs (44)

Histiocytic sarcoma in miniature schnauzers: 30 cases (2020)
Journal Article
Purzycka, K., Peters, L. M., Elliott, J., Lamb, C. R., Priestnall, S. L., Hardas, A., …Rodriguez‐Piza, I. (2020). Histiocytic sarcoma in miniature schnauzers: 30 cases. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13139

Objectives To summarise the clinical presentation and outcomes in a series of miniature schnauzers diagnosed with histiocytic sarcoma. Materials and Methods Retrospective review of medical records of miniature schnauzers diagnosed with histiocyt... Read More about Histiocytic sarcoma in miniature schnauzers: 30 cases.

Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation (2020)
Journal Article
Wu, Y., Chang, Y. M., Polton, G., Stell, A. J., Szladovits, B., Macfarlane, M., …Garden, O. A. (2020). Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation. Frontiers in Oncology, 10, https://doi.org/10.3389/fonc.2020.00307

Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on cell of origin are generally recognized, germinal center B (GCB)-like and activated B cell (A... Read More about Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation.

Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice (2019)
Journal Article
Ying Wu, , Chang, Y. M., Stell, A. J., Priestnall, S. L., Sharma, E., Goulart, M. R., …Garden, O. A. (2019). Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice. https://doi.org/10.1038/s41598-019-50065-8

Regulatory T cells (Tregs) are a double-edged regulator of the immune system. Aberrations of Tregs correlate with pathogenesis of inflammatory, autoimmune and neoplastic disorders. Phenotypically and functionally distinct subsets of Tregs have been i... Read More about Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice.

Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy (2019)
Journal Article
Swaffield, M., Hedley, J., Stapleton, N., Priestnall, S. L., Suárez-Bonnet, A., & Baldrey, V. (2019). Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy. Journal of Exotic Pet Medicine, https://doi.org/10.1053/j.jepm.2019.05.003

A six-month-old male entire ferret presented for investigation of atraumatic bilateral pelvic limb lameness. Radiographic and subsequent histopathological assessment of the femoral heads following bilateral femoral head ostectomy was consistent with... Read More about Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy.

Cutaneous Botryomycosis in Two Pet Rabbits (2018)
Journal Article
Hedley, J., Stapleton, N., Muir, C., Priestnall, S. L., & Smith, K. (2018). Cutaneous Botryomycosis in Two Pet Rabbits. Journal of Exotic Pet Medicine, 28, 143-147. https://doi.org/10.1053/j.jepm.2018.01.005

A 5-year-old male neutered rabbit was presented for assessment of multiple abscesses, which had appeared suddenly over the ventrum, perineum and hindlimbs over the previous few days. Thirteen abscesses were surgically excised. Culture revealed Pseudo... Read More about Cutaneous Botryomycosis in Two Pet Rabbits.

Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig (2018)
Journal Article
Wong, H. E., Hedley, J., Stapleton, N., Murphy, B., & Priestnall, S. L. (2018). Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig. Journal of Veterinary Diagnostic Investigation, https://doi.org/10.1177/1040638718794784

Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas a... Read More about Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig.

Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers (2018)
Journal Article
Beever, L., Swinbourne, F., Priestnall, S. L., Ter Haar, G., & Brockman, D. J. (2018). Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers. Journal of Small Animal Practice, 60(4), 254-260. https://doi.org/10.1111/jsap.12839

Three West Highland white terriers were presented for investigation of left‐sided para‐aural abscessation. CT revealed chronic otitis media with extensive osseous proliferation surrounding the horizontal and vertical ear canals contiguous with the ex... Read More about Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers.

Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry (2018)
Journal Article
Pittaway, R., Wu, Y., Suárez-Bonnet, A., Szladovits, B., Scurrell, E. J., Garden, O. A., …Priestnall, S. L. (2018). Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry. Journal of Veterinary Diagnostic Investigation, https://doi.org/10.1177/1040638718760965

Anaplastic large-cell lymphoma or null-cell lymphoma is a clinical entity reported in people, classified according to the unique appearance of large pleomorphic cells that express CD30. Null-cell lymphoma has also been described in dogs when neither... Read More about Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry.

Retrospective evaluation of COX-2 expression, histological and clinical factors as prognostic indicators in dogs with renal cell carcinomas undergoing nephrectomy (2017)
Journal Article
Carvalho, S., Stoll, A. L., Priestnall, S. L., Suárez-Bonnet, A., Rassnick, K., Lynch, S., …Lara-Garcia, A. (2017). Retrospective evaluation of COX-2 expression, histological and clinical factors as prognostic indicators in dogs with renal cell carcinomas undergoing nephrectomy. Veterinary and Comparative Oncology, 15(4), 1280-1294. https://doi.org/10.1111/vco.12264

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs (2017)
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Chowdary, P., Alibhai, H. I. K., …Agarwal, B. (2017). Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. https://doi.org/10.1038/s41598-017-09508-3

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs wi... Read More about Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.

Imaging diagnosis-computed tomography of traction bronchiectasis secondary to pulmonary fibrosis in a Patterdale Terrier (2017)
Journal Article
Fitzgerald, E., Priestnall, S. L., & Lamb, C. R. (2017). Imaging diagnosis-computed tomography of traction bronchiectasis secondary to pulmonary fibrosis in a Patterdale Terrier. Veterinary Radiology and Ultrasound, 58(4), E42-E44. https://doi.org/10.1111/vru.12403

An 8-year-old, Patterdale terrier was referred for evaluation of tachypnoea, exercise intolerance, and weight loss. Computed tomographic images showed pneumomediastinum, diffuse pulmonary ground glass opacity, and marked dilatation of peripheral bron... Read More about Imaging diagnosis-computed tomography of traction bronchiectasis secondary to pulmonary fibrosis in a Patterdale Terrier.

Genome sequencing reveals a splice donor site mutation in the SNX14 gene associated with a novel cerebellar cortical degeneration in the Hungarian Vizsla dog breed (2016)
Journal Article
Fenn, J. T., Boursnell, M., Hitti, R. J., Jenkins, C. A., Terry, R. L., Priestnall, S. L., …Forman, O. P. (2016). Genome sequencing reveals a splice donor site mutation in the SNX14 gene associated with a novel cerebellar cortical degeneration in the Hungarian Vizsla dog breed. BMC Genetics, 17(1), https://doi.org/10.1186/s12863-016-0433-y

Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma (2016)
Journal Article
Giuliano, A., Swift, R., Arthurs, C., Marote, G., Abramo, F., McKay, J., …Ahmed, A. (2016). Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma. PLoS ONE, 11(8), e0161103. https://doi.org/10.1371/journal.pone.0161103

Feline oral squamous cell carcinoma (FOSCC) is an aggressive neoplasm in cats. Little is known about the possible molecular mechanisms that may be involved in the initiation, maintenance and progression of FOSCC. Wnt signalling is critical in develop... Read More about Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma.

Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study (2015)
Journal Article
Lee, K. C. L., Baker, L. A., Stanzani, G., Alibhai, H. I. K., Chang, Y. M., Palacios, C. J., …Jalan, R. (2015). Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study. Journal of Hepatology, 63(3), 634-642. https://doi.org/10.1016/j.jhep.2015.04.020