All Outputs (2306)

Scent (Apocrine) Gland Adenocarcinoma in a Wedge-Capped Capuchin Monkey (Cebus olivaceus): Histological and Immunohistochemical Features. (2020)
Journal Article
Suárez-Bonnet, A., Priestnall, S. L., Ramírez, G. A., González-Sánchez, C., & Jaber, J. R. (2020). Scent (Apocrine) Gland Adenocarcinoma in a Wedge-Capped Capuchin Monkey (Cebus olivaceus): Histological and Immunohistochemical Features. Journal of Comparative Pathology, 179, 1-6

In humans, apocrine gland tumours encompass a heterogeneous group of uncommon neoplasms with varied and unpredictable biological behaviour. They can be slow-growing lesions, recur after excision, produce lymph node metastasis in up to 50% of cases or... Read More about Scent (Apocrine) Gland Adenocarcinoma in a Wedge-Capped Capuchin Monkey (Cebus olivaceus): Histological and Immunohistochemical Features..

Type I and III interferons disrupt lung epithelial repair during recovery from viral infection (2020)
Journal Article
Major, J., Crotta, S., Llorian, M., McCabe, T. M., Gad, H. H., Priestnall, S. L., Hartmann, R., & Wack, A. (2020). Type I and III interferons disrupt lung epithelial repair during recovery from viral infection. Science, 369(6504), 712-717. https://doi.org/10.1126/science.abc2061

Interferons (IFNs) are central to antiviral immunity. Viral recognition elicits IFN production, which in turn triggers the transcription of IFN-stimulated genes (ISGs), which engage in various antiviral functions. Type I IFNs (IFN-α and IFN-β) are wi... Read More about Type I and III interferons disrupt lung epithelial repair during recovery from viral infection.

Genomic Surveillance of Yellow Fever Virus Epizootic in São Paulo, Brazil, 2016 – 2018 (2020)
Journal Article
Lauring, A. S., Hill, S. C., de Souza, R., Thézé, J., Claro, I., Aguiar, R. S., Abade, L., Santos, F. C. P., Cunha, M. S., Nogueira, J. S., Salles, F. C. S., Rocco, I. M., Maeda, A. Y., Vasami, F. G. S., du Plessis, L., Silveira, P. P., de Jesus, J. G., Quick, J., Fernandes, N. C. C. A., Guerra, J. M., …Faria, N. R. (2020). Genomic Surveillance of Yellow Fever Virus Epizootic in São Paulo, Brazil, 2016 – 2018. PLoS Pathogens, 16(8), e1008699. https://doi.org/10.1371/journal.ppat.1008699

São Paulo, a densely inhabited state in southeast Brazil that contains the fourth most populated city in the world, recently experienced its largest yellow fever virus (YFV) outbreak in decades. YFV does not normally circulate extensively in São Paul... Read More about Genomic Surveillance of Yellow Fever Virus Epizootic in São Paulo, Brazil, 2016 – 2018.

A Systems Analysis and Conceptual System Dynamics Model of the Livestock-derived Food System in South Africa: A Tool for Policy Guidance (2020)
Journal Article
Queenan, K., Sobratee, N., Davids, R., Mabhaudhi, T., Chimonyo, M., Slotow, R., Shankar, B., & Häsler, B. (2020). A Systems Analysis and Conceptual System Dynamics Model of the Livestock-derived Food System in South Africa: A Tool for Policy Guidance. https://doi.org/10.5304/jafscd.2020.094.021

Global food production systems are currently under scrutiny, in particular the health, nutrition, and environmental impacts of livestock-derived food (LDF). Despite South Africa’s recent socio­economic transformation and increased per-capita LDF cons... Read More about A Systems Analysis and Conceptual System Dynamics Model of the Livestock-derived Food System in South Africa: A Tool for Policy Guidance.

Genetic diversity and risk factors for the transmission of antimicrobial resistance across human, animals and environmental compartments in East Africa: a review. (2020)
Journal Article
Katale, B. Z., Misinzo, G., Mshana, S. E., Chiyangi, H., Campino, S., Clark, T. G., Good, L., Rweyemamu, M. M., & Matee, M. I. (2020). Genetic diversity and risk factors for the transmission of antimicrobial resistance across human, animals and environmental compartments in East Africa: a review. Antimicrobial Resistance and Infection Control, 9(1), 127

BACKGROUND

The emergence and spread of antimicrobial resistance (AMR) present a challenge to disease control in East Africa. Resistance to beta-lactams, which are by far the most used antibiotics worldwide and include the penicillins, cephalospori... Read More about Genetic diversity and risk factors for the transmission of antimicrobial resistance across human, animals and environmental compartments in East Africa: a review..

Genetic diversity and risk factors for the transmission of antimicrobial resistance across human, animals and environmental compartments in East Africa: a review (2020)
Journal Article
Katale, B., Misinzo, G., Mshana, S., Chiyangi, H., Campino, S., Clark, T., Good, L., Rweyemamu, M., & Matee, M. (2020). Genetic diversity and risk factors for the transmission of antimicrobial resistance across human, animals and environmental compartments in East Africa: a review. Antimicrobial Resistance and Infection Control, 9(1), https://doi.org/10.1186/s13756-020-00786-7

The emergence and spread of antimicrobial resistance (AMR) present a challenge to disease control in East Africa. Resistance to beta-lactams, which are by far the most used antibiotics worldwide and include the penicillins, cephalosporins, monobactam... Read More about Genetic diversity and risk factors for the transmission of antimicrobial resistance across human, animals and environmental compartments in East Africa: a review.

Nudging in Animal Disease Control and Surveillance: A Qualitative Approach to Identify Strategies Used to Improve Compliance With Animal Health Policies (2020)
Journal Article
Garza, M., Ågren, E. C. C., & Lindberg, A. (2020). Nudging in Animal Disease Control and Surveillance: A Qualitative Approach to Identify Strategies Used to Improve Compliance With Animal Health Policies. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00383

Professionals from seven European countries were interviewed to identify strategies used in the surveillance and control of animal infections to influence behaviors such as program enrollment, adoption of biosecurity measures, and engagement in surve... Read More about Nudging in Animal Disease Control and Surveillance: A Qualitative Approach to Identify Strategies Used to Improve Compliance With Animal Health Policies.

Epidemiological and clinical characteristics of the COVID-19 epidemic in Brazil (2020)
Journal Article
de Souza, W. M., Buss, L. F., Candido, D. A., Carrera, J. P., Li, S., Zarebski, A. E., Pereira, R. H. M., Prete, C. A., de Souza-Santos, A. A., Parag, K. V., Belotti, M. C. T. D., Vincenti-Gonzalez, M. F., Messina, J., da Silva Sales, F. C., Andrade, P. S., Nascimento, V. H., Ghilardi, F., Abade, L., Gutierrez, B., Kraemer, M. U. G., …Faria, N. R. (2020). Epidemiological and clinical characteristics of the COVID-19 epidemic in Brazil. Nature Human Behaviour, 4(8), 856-865

The first case of COVID-19 was detected in Brazil on 25 February 2020. We report and contextualize epidemiological, demographic and clinical findings for COVID-19 cases during the first 3 months of the epidemic. By 31 May 2020, 514,200 COVID-19 cases... Read More about Epidemiological and clinical characteristics of the COVID-19 epidemic in Brazil.

Cas13b-dependent and Cas13b-independent RNA knockdown of viral sequences in mosquito cells following guide RNA expression (2020)
Journal Article
Tng, P. Y. L., Carabajal Paladino, L., Verkuijl, S. A. N., Purcell, J., Merits, A., Leftwich, P. T., Fragkoudis, R., Noad, R., & Alphey, L. (2020). Cas13b-dependent and Cas13b-independent RNA knockdown of viral sequences in mosquito cells following guide RNA expression. Communications Biology, 3(1), https://doi.org/10.1038/s42003-020-01142-6

Aedes aegypti and Aedes albopictus mosquitoes are vectors of the RNA viruses chikungunya (CHIKV) and dengue that currently have no specific therapeutic treatments. The
development of new methods to generate virus-refractory mosquitoes would be benef... Read More about Cas13b-dependent and Cas13b-independent RNA knockdown of viral sequences in mosquito cells following guide RNA expression.

In vitro Anticoccidial Study of Oregano and Garlic Essential Oils and Effects on Growth Performance, Fecal Oocyst Output, and Intestinal Microbiota in vivo (2020)
Journal Article
Sidiropoulou, E., Skoufos, I., Marugan-Hernandez, V., Giannenas, I., Bonos, E., Aguiar-Martins, K., Lazari, D., Blake, D., & Tzora, A. (2020). In vitro Anticoccidial Study of Oregano and Garlic Essential Oils and Effects on Growth Performance, Fecal Oocyst Output, and Intestinal Microbiota in vivo. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00420

This study investigated the in vitro effects of Greek oregano and garlic essential oils on inhibition of Eimeria parasites and their in vivo effects on production performance, intestinal bacteria counts, and oocyst output. An inhibition assay was per... Read More about In vitro Anticoccidial Study of Oregano and Garlic Essential Oils and Effects on Growth Performance, Fecal Oocyst Output, and Intestinal Microbiota in vivo.

Dogs Don’t Die Just in Hot Cars—Exertional Heat-Related Illness (Heatstroke) Is a Greater Threat to UK Dogs (2020)
Journal Article
Hall, E. J., Carter, A. J., & O’Neill, D. G. (2020). Dogs Don’t Die Just in Hot Cars—Exertional Heat-Related Illness (Heatstroke) Is a Greater Threat to UK Dogs. Animals, 10(8), 1324. https://doi.org/10.3390/ani10081324

Heat-related illness will affect increasing numbers of dogs as global temperatures rise unless e↵ective mitigation strategies are implemented. This study aimed to identify the key triggers of heat-related illness in dogs and investigate canine risk f... Read More about Dogs Don’t Die Just in Hot Cars—Exertional Heat-Related Illness (Heatstroke) Is a Greater Threat to UK Dogs.

Equine asthma: current understanding and future directions (2020)
Journal Article
Couetil, L., Cardwell, J., Leguillette, R., Mazan, M., Richard, E., Bienzle, D., Bullone, M., Gerber, V., Ivester, K., Lavoie, J., Martin, J., Moran, G., Niedźwiedź, A., Pusterla, N., & Swiderski, C. (2020). Equine asthma: current understanding and future directions. Frontiers in Veterinary Science, 7(450), 1-21. https://doi.org/10.3389/fvets.2020.00450

The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed... Read More about Equine asthma: current understanding and future directions.

Possible Drivers of the 2019 Dengue Outbreak in Bangladesh: The Need for a Robust Community-Level Surveillance System (2020)
Journal Article
Ahsan, A., Haider, N., Kock, R., Benfield, C., & Reisen, W. (2020). Possible Drivers of the 2019 Dengue Outbreak in Bangladesh: The Need for a Robust Community-Level Surveillance System. Journal of Medical Entomology, https://doi.org/10.1093/jme/tjaa150

Bangladesh experienced its largest dengue virus (DENV) outbreak in 2019, with 101,354 patients admitted to hospital with either laboratory confirmed or clinical diagnosis. By contrast, the cumulative number of dengue patients admitted to hospitals in... Read More about Possible Drivers of the 2019 Dengue Outbreak in Bangladesh: The Need for a Robust Community-Level Surveillance System.

Knowledge, Attitudes and Practices of Veterinarians Towards Antimicrobial Resistance and Stewardship in Nigeria (2020)
Journal Article
Adekanye, U., Ekiri, A., Galipó, E., Muhammad, A., Mateus, A., La Ragione, R., Wakawa, A., Armson, B., Mijten, E., Alafiatayo, R., Varga, G., & Cook, A. (2020). Knowledge, Attitudes and Practices of Veterinarians Towards Antimicrobial Resistance and Stewardship in Nigeria. Antibiotics, https://doi.org/10.3390/antibiotics9080453

Abstract: Antimicrobial resistance (AMR) is a global health concern and the inappropriate use of antibiotics in animals and humans are considered contributing factors. A cross-sectional survey to assess the knowledge, attitudes and practices of veter... Read More about Knowledge, Attitudes and Practices of Veterinarians Towards Antimicrobial Resistance and Stewardship in Nigeria.

Prognostic factors and proposed grading system for cutaneous and subcutaneous soft tissue sarcomas in cats, based on a retrospective study (2020)
Journal Article
Dobromylskyj, M. J., Richards, V., & Smith, K. C. (2020). Prognostic factors and proposed grading system for cutaneous and subcutaneous soft tissue sarcomas in cats, based on a retrospective study. Journal of Feline Medicine and Surgery, 1098612X2094239. https://doi.org/10.1177/1098612x20942393

Objectives
The objectives of this study included utilising a large database from a diagnostic laboratory to identify any breed, sex or age predilections for cutaneous and subcutaneous soft tissue sarcomas (STSs), and the most common anatomical locat... Read More about Prognostic factors and proposed grading system for cutaneous and subcutaneous soft tissue sarcomas in cats, based on a retrospective study.

Moxidectin: an oral treatment for human onchocerciasis (2020)
Journal Article
Milton, P., Hamley, J., Walker, M., & Basáñez, M. (2020). Moxidectin: an oral treatment for human onchocerciasis. Expert Review of Anti-infective Therapy, 1-15. https://doi.org/10.1080/14787210.2020.1792772

Moxidectin is a milbemycin endectocide recently approved for the treatment of human onchocerciasis. Onchocerciasis, earmarked for elimination of transmission, is a filarial infection endemic in Africa, Yemen, and the Amazonian focus straddling Venezu... Read More about Moxidectin: an oral treatment for human onchocerciasis.

Investigation of correlations between clinical signs and pathological findings in cats and dogs with inflammatory bowel disease (2020)
Journal Article
Farray, D., Rodriguez, F., Ravelo-Garcìa, A., Suarez-Bonne, A., Francisco-Arteaga, C., & Jaber, J. R. (2020). Investigation of correlations between clinical signs and pathological findings in cats and dogs with inflammatory bowel disease

This paper compares the correlation between the clinical signs and the histopathological observations of the entire intestine in cats and dogs with inflammatory bowel disease (IBD). To perform this study, hospital records of 53 dogs and 20 cats of di... Read More about Investigation of correlations between clinical signs and pathological findings in cats and dogs with inflammatory bowel disease.

Low prevalence of Batrachochytrium dendrobatidis detected in amphibians from Vietnam’s highest mountains (2020)
Journal Article
Tapley, B., Jervis, P., Thanh Nguyen, L., Portway, C., Thanh Nguyen, C., Van Luong, H., Kane, D., Brookes, L., Perkins, M., Ghosh, P., Wierzbicki, C., Shelton, J., Fisher, M., & Rowley, J. (in press). Low prevalence of Batrachochytrium dendrobatidis detected in amphibians from Vietnam’s highest mountains

The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGFβ Signaling (2020)
Journal Article
Pseftogas, A., Xanthopoulos, K., Poutahidis, T., Ainali, C., Dafou, D., Panteris, E., Kern, J., Varelas, X., Hardas, A., Gonidas, C., Tsingotjidou, A., Hatzivassiliou, E., & Mosialos, G. (2020). The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGFβ Signaling. Cancers, 12(8), 2047. https://doi.org/10.3390/cancers12082047

Downregulation of the cylindromatosis (CYLD) tumor suppressor has been associated with breast cancer development and progression. Here, we report a critical role for CYLD in maintaining the phenotype of mammary epithelial cells in vitro and in vivo.... Read More about The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGFβ Signaling.

Evolution and epidemic spread of SARS-CoV-2 in Brazil (2020)
Journal Article
Candido, D. S., Claro, I. M., de Jesus, J. G., Souza, W. M., Moreira, F. R. R., Dellicour, S., Mellan, T. A., du Plessis, L., Pereira, R. H. M., Sales, F. C. S., Manuli, E. R., Thézé, J., Almeida, L., Menezes, M. T., Voloch, C. M., Fumagalli, M. J., Coletti, T. M., da Silva, C. A. M., Ramundo, M. S., Amorim, M. R., …Faria, N. (2020). Evolution and epidemic spread of SARS-CoV-2 in Brazil. Science, eabd2161. https://doi.org/10.1126/science.abd2161

Brazil currently has one of the fastest growing SARS-CoV-2 epidemics in the world. Owing to limited available data, assessments of the impact of non-pharmaceutical interventions (NPIs) on virus spread remain challenging. Using a mobility-driven trans... Read More about Evolution and epidemic spread of SARS-CoV-2 in Brazil.