Skip to main content

Research Repository

Advanced Search

All Outputs (317)

Thirty-two cats with effusive or non-effusive feline infectious peritonitis treated with a combination of remdesivir and GS-441524 (2023)
Journal Article
Green, J., Syme, H., & Tayler, S. (2023). Thirty-two cats with effusive or non-effusive feline infectious peritonitis treated with a combination of remdesivir and GS-441524. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16804

BackgroundGS-441524 has been successfully used to treat feline infectious peritonitis (FIP) in cats. However, the use of its prodrug, remdesivir, in combination with a PO GS-441524 containing product for the treatment of FIP has not yet been describe... Read More about Thirty-two cats with effusive or non-effusive feline infectious peritonitis treated with a combination of remdesivir and GS-441524.

Is UK Puppy Purchasing Suffering a Long COVID Effect? Ongoing Negative Impacts of the COVID-19 Pandemic upon Puppy Purchase Motivations and Behaviours in 2021 (2023)
Journal Article
Brand, C., Packer, R., Brand, C., Belshaw, Z., Pegram, C., Dale, F., …O'Neill, D. (2023). Is UK Puppy Purchasing Suffering a Long COVID Effect? Ongoing Negative Impacts of the COVID-19 Pandemic upon Puppy Purchase Motivations and Behaviours in 2021. Animals, 13(13), 2186. https://doi.org/10.3390/ani13132186

The COVID-19 pandemic led to a surge in acquisitions of puppies in the UK, dubbed the “Pandemic Puppy” phenomenon. In addition to an increased demand for puppies, widespread changes to both why and how puppies were purchased during this period compar... Read More about Is UK Puppy Purchasing Suffering a Long COVID Effect? Ongoing Negative Impacts of the COVID-19 Pandemic upon Puppy Purchase Motivations and Behaviours in 2021.

Effect of a specially formulated diet on progression of heart enlargement in dogs with subclinical degenerative mitral valve disease (2023)
Journal Article
Oyama, M., Scansen, B., Boswood, A., Goldfeder, G., Rosenthal, S., Cober, R., …Li, Q. (2023). Effect of a specially formulated diet on progression of heart enlargement in dogs with subclinical degenerative mitral valve disease. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16796

BackgroundPrevious studies in dogs with degenerative mitral valve disease (DMVD) have identified altered myocardial energy metabolism and oxidation, which might contribute to cardiac hypertrophy. Diets rich in medium chain fatty acids and antioxidant... Read More about Effect of a specially formulated diet on progression of heart enlargement in dogs with subclinical degenerative mitral valve disease.

Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM (2023)
Journal Article
Beeston, D., & Cortellini, S. (in press). Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM. Veterinary Record,

This case report details the clinical investigation of an 11-month intact male Cockapoo who presented with acute left forebrain signs associated with suspected intra-cranial haemorrhage due to Angiostrongylus vasorum. Initial investigations faile... Read More about Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM.

Urinary bladder hemangiosarcoma in a cat treated with partial cystectomy and adjuvant metronomic cyclophosphamide and thalidomide (2023)
Journal Article
McNally, A., Rossanese, M., Suárez‐Bonnet, A., Hardas, A., & Yale, A. D. (in press). Urinary bladder hemangiosarcoma in a cat treated with partial cystectomy and adjuvant metronomic cyclophosphamide and thalidomide. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16750

Visceral hemangiosarcomas (HSA) are rare in cats and typically associated with aggressive biologic behavior and poor prognosis. A 4-year-old male neutered domestic shorthair cat was presented with a 3-month history of hematuria and stranguria; ultras... Read More about Urinary bladder hemangiosarcoma in a cat treated with partial cystectomy and adjuvant metronomic cyclophosphamide and thalidomide.

Effects of individual and pair housing of calves on short term health and behaviour on a UK commercial dairy farm (2023)
Journal Article
Mahendran, S., Blackie, N., Wathes, C., & booth, R. (2023). Effects of individual and pair housing of calves on short term health and behaviour on a UK commercial dairy farm. Animals, https://doi.org/10.3390/ani13132140

Social pair housing of calves has previously demonstrated positive impacts on calf health and productivity compared to individual housing, but much of the research has been conducted in research institutions in different environmental conditions to t... Read More about Effects of individual and pair housing of calves on short term health and behaviour on a UK commercial dairy farm.

Saddle Thigh Block Design Can Influence Rider and Horse Biomechanics (2023)
Journal Article
Murray, R., Fisher, M., Fairfax, V., & MacKechnie-Guire, R. (2023). Saddle Thigh Block Design Can Influence Rider and Horse Biomechanics. Animals, 13(13), https://doi.org/10.3390/ani13132127

Simple Summary There is increasing interest in the effect of saddle design on horse kinematics, but little evidence of the influence on rider-saddle interaction and how this affects horse movement patterns. We aimed to investigate the effect of chang... Read More about Saddle Thigh Block Design Can Influence Rider and Horse Biomechanics.

The Gordon Memorial Lecture: Laying hen welfare (2023)
Journal Article
Nicol, C. (2023). The Gordon Memorial Lecture: Laying hen welfare. British Poultry Science, 64(4), 441-447. https://doi.org/10.1080/00071668.2023.2211891

reference tests remain a useful tool in the assessment of laying hen welfare and have been used to establish what types of resources and enrichments are most likely to meet the birds’ needs. Evidence on the underlying structure of bird preference sug... Read More about The Gordon Memorial Lecture: Laying hen welfare.

Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy (2023)
Journal Article
Cheng, W., Lawson, C., Liu, H., Wilkie, L., Dobromylskyj, M., Fuentes, V. L., …Connolly, D. J. (2023). Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy. Animals, 13(13), 2112. https://doi.org/10.3390/ani13132112

Simple Summary: The hallmark changes in hypertrophic cardiomyopathy (HCM), a naturally occurring heart disease in both humans and cats, are left ventricular hypertrophy (LVH) and myocardial fibrosis. Key myocardial proteins, lumican, lysyl oxidase (L... Read More about Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy.

Are there substandard amoxicillin/clavulanic acid oral formulations for intended veterinary use in Malaysia, the United Kingdom, Serbia and Thailand? A convenience sampling study (2023)
Journal Article
Pelligand, L., Baker, D., Sivagurunathan, A., Kovačević, Z., Suemanotham, N., Stair, J. L., …Steagall, P. V. (in press). Are there substandard amoxicillin/clavulanic acid oral formulations for intended veterinary use in Malaysia, the United Kingdom, Serbia and Thailand? A convenience sampling study. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13648

Objectives: Antimicrobial formulations of substandard quality have negative consequences for efficacy in patients and potentially promote antimicrobial resistance. Amoxicillin/clavulanate (AMC) is the most commonly used oral antimicrobial drug in com... Read More about Are there substandard amoxicillin/clavulanic acid oral formulations for intended veterinary use in Malaysia, the United Kingdom, Serbia and Thailand? A convenience sampling study.

Characterisation of Canine Intestinal MicroRNA Expression in Inflammatory Bowel Disease and T-Cell Lymphoma (2023)
Journal Article
Williams, J., Werling, D., Davison, L., Hiron, T., & Xia, D. (in press). Characterisation of Canine Intestinal MicroRNA Expression in Inflammatory Bowel Disease and T-Cell Lymphoma. Journal of Comparative Pathology, https://doi.org/10.1016/j.jcpa.2023.03.186

Differentiating between canine inflammatory bowel disease and intestinal T-cell lymphoma via histopathological examination of endoscopically-derived intestinal biopsies can be challenging and involves an invasive procedure requiring specialised equip... Read More about Characterisation of Canine Intestinal MicroRNA Expression in Inflammatory Bowel Disease and T-Cell Lymphoma.

A Review of Clinical Outcomes, Owner Understanding and Satisfaction following Medial Canthoplasty in Brachycephalic Dogs in a UK Referral Setting (2016–2021) (2023)
Journal Article
Andrews, A. L. M. M., Youngman, K. L., Packer, R. M. A., O’Neill, D. G., & Kafarnik, C. (in press). A Review of Clinical Outcomes, Owner Understanding and Satisfaction following Medial Canthoplasty in Brachycephalic Dogs in a UK Referral Setting (2016–2021). Animals, 13(12), 2032. https://doi.org/10.3390/ani13122032

Users’ perception of the OH-EpiCap evaluation tool based on its application to nine national antimicrobial resistance surveillance systems (2023)
Journal Article
Moura, P., Collineau, L., Sandberg, M., Tomassone, L., De Meneghi, D., Norström, M., …Alban, L. (in press). Users’ perception of the OH-EpiCap evaluation tool based on its application to nine national antimicrobial resistance surveillance systems. Frontiers in Public Health, 11, https://doi.org/10.3389/fpubh.2023.1138645

Introduction: Antimicrobial resistance (AMR) is a One Health (OH) challenge. To achieve or maintain an effective and efficient AMR surveillance system, it is crucial to evaluate its performance in meeting the proposed objectives, while complying with... Read More about Users’ perception of the OH-EpiCap evaluation tool based on its application to nine national antimicrobial resistance surveillance systems.

Heterotopic Ossification of the Soft Tissues Overlying the Carpal Bones of a 2-year-old Bearded Dragon (Pogona vitticeps) (2023)
Journal Article
Robson, L., Baldrey, V., Hedley, J., Yaffy, D., & Harrington, N. (2023). Heterotopic Ossification of the Soft Tissues Overlying the Carpal Bones of a 2-year-old Bearded Dragon (Pogona vitticeps). Journal of Herpetological Medicine and Surgery, 33(2), 96-100. https://doi.org/10.5818/jhms-d-22-00044

A 2-yr-old female bearded dragon (Pogona vitticeps) presented to the clinic exhibiting lameness and significant swellings bilaterally in the carpal region. On physical examination the lizard was determined to be in obese body condition and pododermat... Read More about Heterotopic Ossification of the Soft Tissues Overlying the Carpal Bones of a 2-year-old Bearded Dragon (Pogona vitticeps).

Clinical presentation, diagnosis, treatment, and outcome in 8 dogs and 2 cats with global hypoxic-ischemic brain injury (2010-2022) (2023)
Journal Article
Crawford, A., Beltran, E., Danciu, C., & Yaffy, D. (2023). Clinical presentation, diagnosis, treatment, and outcome in 8 dogs and 2 cats with global hypoxic-ischemic brain injury (2010-2022). Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16790

BackgroundGlobal hypoxic-ischemic brain injury (GHIBI) results in variable degrees of neurological dysfunction. Limited data exists to guide prognostication on likelihood of functional recovery. HypothesisProlonged duration of hypoxic-ischemic insult... Read More about Clinical presentation, diagnosis, treatment, and outcome in 8 dogs and 2 cats with global hypoxic-ischemic brain injury (2010-2022).

Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression in three-dimensional culture which can be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signaling (2023)
Journal Article
Beaumont, R. E., Smith, E. J., Zhou, L., Marr, N., Thorpe, C. T., & Guest, D. J. (in press). Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression in three-dimensional culture which can be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signaling. Molecular and Cellular Biochemistry, https://doi.org/10.1007/s11010-023-04779-z