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All Outputs (235)

Randomized placebo-controlled clinical trial of a new chewable formulation of amlodipine for the treatment of hypertension in client-owned cats (2015)
Journal Article
Huhtinen, M., Derre, G., Renoldi, H. J., Rinkinen, M., Adler, K., Aspegren, J., Zemirline, C., & Elliott, J. (2015). Randomized placebo-controlled clinical trial of a new chewable formulation of amlodipine for the treatment of hypertension in client-owned cats. Journal of Veterinary Internal Medicine, 29(3), 786-793. https://doi.org/10.1111/jvim.12589

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae (2015)
Journal Article
Bossé, J. T., Li, Y., Walker, S., Atherton, T., Crespo, R. F., Williamson, S. M., Rogers, J., Chaudhuri, R. R., Weinert, L. A., Oshota, O., Holden, M. T. G., Maskell, D. J., Tucker, A. W., Wren, B. W., Rycroft, A. N., Langford, P. R., & BRaDP1T Consortium. (2015). Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae. Journal of Antimicrobial Chemotherapy, 70(8), 2217-2222. https://doi.org/10.1093/jac/dkv121

Continuing professional development: learning that leads to change in individual and collective clinical practice (2015)
Journal Article
May, S. A., & Kinnison, T. (2015). Continuing professional development: learning that leads to change in individual and collective clinical practice. Veterinary Record, 177(1), 13-13. https://doi.org/10.1136/vr.103109

The lack of effectiveness of traditional models of continuing professional development is increasingly recognised. While they can lead to increased knowledge of participants, research suggests that there is a general failure to produce meaningful and... Read More about Continuing professional development: learning that leads to change in individual and collective clinical practice.

Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis (2015)
Journal Article
Zolfaghari, P. S., Carré, J. E., Parker, N., Curtin, N. A., Duchen, M. R., & Singer, M. (2015). Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis. https://doi.org/10.1152/ajpendo.00562.2014

Muscle dysfunction is a common feature of severe sepsis and multi-organ failure. Recent evidence implicates bioenergetic dysfunction and oxidative damage as important underlying pathophysiological mechanisms. Increased abundance of uncoupling protein... Read More about Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis.

Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip (2015)
Journal Article
Williams, J. M., Duckworth, C. A., Burkitt, M. D., Watson, A. J., Campbell, B. J., & Pritchard, D. M. (2015). Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip. Veterinary Pathology, 523(3), 445-55. https://doi.org/10.1177/0300985814559404

The intestinal epithelium is a critical component of the gut barrier. Composed of a single layer of intestinal epithelial cells (IECs) held together by tight junctions, this delicate structure prevents the transfer of harmful microorganisms, antigens... Read More about Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip.

Challenges of pastoral cattle production in a sub-humid zone of Nigeria (2015)
Journal Article
Suleiman, A., Jackson, E. L., & Rushton, J. (2015). Challenges of pastoral cattle production in a sub-humid zone of Nigeria. Tropical Animal Health and Production, 47(6), 1177-85. https://doi.org/10.1007/s11250-015-0845-0

More than 80 % of the 20 million heads of Nigerian cattle are kept by pastoral households. As such, optimal herd management is important in maintaining human nutrition, livelihoods and socio-cultural balance. This study was conducted to contribute to... Read More about Challenges of pastoral cattle production in a sub-humid zone of Nigeria.

PinR mediates the generation of reversible population diversity in Streptococcus zooepidemicus (2015)
Journal Article
Steward, K. F., Harrison, T., Robinson, C., Slater, J. D., Maskell, D. J., Harris, S. R., Holden, M. T. G., & Waller, A. S. (2015). PinR mediates the generation of reversible population diversity in Streptococcus zooepidemicus. Microbiology, 161, 1105-1112. https://doi.org/10.1099/mic.0.000057

Opportunistic pathogens must adapt to and survive in a wide range of complex ecosystems. Streptococcus zooepidemicus is an opportunistic pathogen of horses and many other animals, including humans. The assembly of different surface architecture pheno... Read More about PinR mediates the generation of reversible population diversity in Streptococcus zooepidemicus.

Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme (2015)
Journal Article
Sanchez-Lara, A. C., Elliott, J., Syme, H. M., Brown, C. A., & Haylor, J. L. (2015). Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme. Veterinary Pathology, 52(3), 513-523. https://doi.org/10.1177/0300985814542811

Chronic kidney disease is a major cause of morbidity and mortality in cats. Transglutaminase 2 (TG2) is a calcium-dependent enzyme proposed to mediate tubulointerstitial fibrosis in the kidney by cross-linking collagen fibrils. Postmortem kidney tiss... Read More about Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme.

Vaccination of Cattle with the N Terminus of LppQ of Mycoplasma mycoides subsp. mycoides Results in Type III Immune Complex Disease upon Experimental Infection (2015)
Journal Article
Mulongo, M., Frey, J., Smith, K. C., Schnier, C., Wesonga, H., Naessens, J., & McKeever, D. J. (2015). Vaccination of Cattle with the N Terminus of LppQ of Mycoplasma mycoides subsp. mycoides Results in Type III Immune Complex Disease upon Experimental Infection. Infection and Immunity, 83(5), 1992-2000. https://doi.org/10.1128/iai.00003-15

Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study (2015)
Journal Article
Lee, K. C. L., Baker, L. A., Stanzani, G., Alibhai, H. I. K., Chang, Y. M., Palacios, C. J., Leckie, P. J., Giordano, P., Priestnall, S. L., Antoine, D. J., Jenkins, R. E., Goldring, C. E., Park, B.-K., Andreola, F., Agarwal, B., Mookerjee, R. P., Davies, N. A., & Jalan, R. (2015). Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study. Journal of Hepatology, 63(3), 634-642. https://doi.org/10.1016/j.jhep.2015.04.020

Development and validation of a melanoma risk score based on pooled data from 16 case-control studies (2015)
Journal Article
Davies, J. R., Chang, Y. M., Bishop, D. T., Armstrong, B. K., Bataille, V., Bergman, W., Berwick, M., Bracci, P. M., Elwood, J. M., Ernstoff, M. S., Green, A., Gruis, N. A., Holly, E. A., Ingvar, C., Kanetsky, P. A., Karagas, M. R., Lee, T. K., Marchand, L. L., Mackie, R. M., Olsson, H., …Newton-Bishop, J. A. (2015). Development and validation of a melanoma risk score based on pooled data from 16 case-control studies. https://doi.org/10.1158/1055-9965.EPI-14-1062

Nuclear receptors in vascular biology (2015)
Journal Article
Bishop-Bailey, D. (2015). Nuclear receptors in vascular biology. Current Atherosclerosis Reports, 17(5), https://doi.org/10.1007/s11883-015-0507-8

Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics. In response to these diverse but critica... Read More about Nuclear receptors in vascular biology.

Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise (2015)
Journal Article
Spiesz, E. M., Thorpe, C. T., Chaudhry, S., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. (2015). Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise. Journal of Orthopaedic Research, 33(6), 889-97. https://doi.org/10.1002/jor.22879

The role of inflammation in tendon injury is uncertain and a topic of current interest. In vitro studies of tendon accelerated overload damage can serve as a valuable source of information on the early stages of tendinopathy. Viable fascicle bundles... Read More about Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise.

Evidence for Negative Selection at SNPs Increasing Dietary Choline Requirement in a Gambian Cohort (2015)
Journal Article
Silver, M. J., Corbin, K. D., Hellenthal, G., Da Costa, K. A., Dominguez-Salas, P., Moore, S. E., Owen, J., Prentice, A. M., Hennig, B. J., & Zeishel, S. H. (2015). Evidence for Negative Selection at SNPs Increasing Dietary Choline Requirement in a Gambian Cohort. FASEB Journal, 29(8), 3426-35. https://doi.org/10.1096/fj.15-271056

Choline is an essential nutrient, and the amount needed in the diet is modulated by several factors. Given geographical differences in dietary choline intake and disparate frequencies of single-nucleotide polymorphisms (SNPs) in choline metabolism ge... Read More about Evidence for Negative Selection at SNPs Increasing Dietary Choline Requirement in a Gambian Cohort.