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Reversing Age Related Changes of the Laryngeal Muscles by Chronic Electrostimulation of the Recurrent Laryngeal Nerve (2016)
Journal Article
Karbiener, M., Jarvis, J. C., Perkins, J. D. M., Lanmueller, H., Schmoll, M., Rode, H. S., …Gugatschka, M. (2016). Reversing Age Related Changes of the Laryngeal Muscles by Chronic Electrostimulation of the Recurrent Laryngeal Nerve. PLoS ONE, 11(11), https://doi.org/10.1371/journal.pone.0167367

Age related atrophy of the laryngeal muscles -mainly the thyroarytenoid muscle (TAM)- leads to a glottal gap and consequently to a hoarse and dysphonic voice that significantly affects quality of life. The aim of our study was to reverse this atrophy... Read More about Reversing Age Related Changes of the Laryngeal Muscles by Chronic Electrostimulation of the Recurrent Laryngeal Nerve.

Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model (2016)
Journal Article
Miller, J. L., Spiro, S. G., Dowall, S. D., Taylor, I., Rule, A., Alonzi, D. S., …Zitzmann, N. (2016). Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model. PLoS ONE, 11(11), e0167018. https://doi.org/10.1371/journal.pone.0167018

The antiviral properties of iminosugars have been reported previously in vitro and in small animal models against Ebola virus (EBOV); however, their effects have not been tested in larger animal models such as guinea pigs. We tested the iminosugars N... Read More about Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model.

Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting (2016)
Journal Article
Bergquist, H., Rocha, C. S., Alvarez-Asencio, R., Nguyen, C. H., Rutland, M. W., Smith, C. I., …Zain, R. (2016). Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting. PLoS ONE, 15(11), e0165788. https://doi.org/10.1371/journal.pone.0165788

Expansion of (GAA)n repeats in the first intron of the Frataxin gene is associated with reduced mRNA and protein levels and the development of Friedreich’s ataxia. (GAA)n expansions form non-canonical structures, including intramolecular triplex (H-D... Read More about Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting.

An Age-Associated Decline in Thymic Output Differs in Dog Breeds According to Their Longevity (2016)
Journal Article
Holder, A., Mella, S., Palmer, D. B., Aspinall, R., & Catchpole, B. (2016). An Age-Associated Decline in Thymic Output Differs in Dog Breeds According to Their Longevity. PLoS ONE, 11, e0165968. https://doi.org/10.1371/journal.pone.0165968

The age associated decline in immune function is preceded in mammals by a reduction in thymic output. Furthermore, there is increasing evidence of a link between immune competence and lifespan. One approach to determining thymic output is to quantify... Read More about An Age-Associated Decline in Thymic Output Differs in Dog Breeds According to Their Longevity.

Methods and Processes of Developing the Strengthening the Reporting of Observational Studies in Epidemiology – Veterinary (STROBE-Vet) Statement (2016)
Journal Article
Sargeant, J. M., O'Connor, A. M., Dohoo, I. R., Erb, H. N., Cevallos, M., Egger, M., …Ward, M. P. (2016). Methods and Processes of Developing the Strengthening the Reporting of Observational Studies in Epidemiology – Veterinary (STROBE-Vet) Statement. Journal of Veterinary Internal Medicine, 30, 1887-1895. https://doi.org/10.1111/jvim.14574

Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology—Veterinary Extension (2016)
Journal Article
O'Connor, A. M., Sargeant, J. M., Dohoo, I. R., Erb, H. N., Cevallos, M., Egger, M., …Ward, M. P. (2016). Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology—Veterinary Extension. Journal of Veterinary Internal Medicine, 30, 1896-1928. https://doi.org/10.1111/jvim.14592