Skip to main content

Research Repository

Advanced Search

All Outputs (458)

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study (2017)
Journal Article
Noyce, A. J., Kia, D. A., Hemani, G., Nicolas, A., Price, T. R., De Pablo-Fernandez, E., Haycock, P. C., Lewis, P. A., Foltynie, T., Smith, G. D., Schrag, A., Lees, A. J., Hardy, J., Singleton, A., Nalls, M. A., Pearce, N., Lawlor, D. A., & Wood, N. W. (2017). Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study. PLoS Medicine, 14(6), https://doi.org/10.1371/journal.pmed.1002314

Both positive and negative associations between higher body mass index (BMI) and Parkinson disease (PD) have been reported in observational studies, but it has been difficult to establish causality because of the possibility of residual confounding o... Read More about Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.

Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014 (2017)
Journal Article
Hernandez-Garcia, J., Wang, J., Restif, O., Holmes, M. A., Mather, A. E., Weinert, L. A., Wileman, T. M., Thomson, J. R., Langford, P. R., Wren, B. W., Rycroft, A. N., Maskell, D. J., & Tucker, A. W. (2017). Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014. Veterinary Microbiology, 207, 117-124. https://doi.org/10.1016/j.vetmic.2017.06.002

Antimicrobial resistance in Streptococcus suis, a global zoonotic pathogen of pigs, has been mostly studied only in diseased animals using surveys that have not evaluated changes over time.

We compared patterns of resistance between S. suis isolat... Read More about Patterns of antimicrobial resistance in Streptococcus suis isolates from pigs with or without streptococcal disease in England between 2009 and 2014.

Use of a Granulocyte Immunofluorescence Assay Designed for Humans for Detection of Antineutrophil Cytoplasmic Antibodies in Dogs with Chronic Enteropathies (2017)
Journal Article
Florey, J., Viall, A., Streu, S., DiMuro, V., Riddle, A. L., Kirk, J., Perazzotti, L., Affeldt, K., Wagner, R., Vaden, S. L., Harris, T., & Allenspach, K. (2017). Use of a Granulocyte Immunofluorescence Assay Designed for Humans for Detection of Antineutrophil Cytoplasmic Antibodies in Dogs with Chronic Enteropathies. Journal of Veterinary Internal Medicine, 31(4), 1062-1066. https://doi.org/10.1111/jvim.14774

Perinuclear antineutrophil cytoplasmic antibodies (pANCA) previously have been shown to be serum markers in dogs with chronic enteropathies, with dogs that have food‐responsive disease (FRD) having higher frequencies of seropositivity than dogs with... Read More about Use of a Granulocyte Immunofluorescence Assay Designed for Humans for Detection of Antineutrophil Cytoplasmic Antibodies in Dogs with Chronic Enteropathies.

Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats (2017)
Journal Article
Crossley, V. J., Debnath, A., Chang, Y. M., Fowkes, R. C., Elliott, J., & Syme, H. M. (2017). Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats. Journal of Veterinary Internal Medicine, 31(4), 1028-1034. https://doi.org/10.1111/jvim.14737

Hyperthyroidism is very common in older cats, but the etiopathogenesis is poorly understood. Decreased risk of hyperthyroidism has been reported in certain colorpoint breeds, and this observation previously has been hypothesized to result from relati... Read More about Breed, Coat Color, and Hair Length as Risk Factors for Hyperthyroidism in Cats.

Regulation of bone mineral density in the grey squirrel, Sciurus carolinensis: Bioavailability of calcium oxalate, and implications for bark stripping (2017)
Journal Article
Nichols, C. P., Gregory, N. G., Goode, N., Gill, R. M. A., & Drewe, J. A. (2017). Regulation of bone mineral density in the grey squirrel, Sciurus carolinensis: Bioavailability of calcium oxalate, and implications for bark stripping. Journal of Animal Physiology and Animal Nutrition, 102(1), https://doi.org/10.1111/jpn.12740

Acute BVDV infection inhibits expression of interferon-stimulated genes during pregnancy recognition in bovine endometrium (2017)
Journal Article
Cheng, Z. R., Chauhan, L., Barry, A. T., Abudureyimu, A., Oguejiofor, C. F., Chen, X., & Wathes, D. C. (2017). Acute BVDV infection inhibits expression of interferon-stimulated genes during pregnancy recognition in bovine endometrium. Biology of Reproduction, 96(6), 1142-1152. https://doi.org/10.1093/biolre/iox056

Bovine viral diarrhea virus (BVDV) can evade host detection by downregulation of interferon signaling pathways. Infection of cows with noncytopathic (ncp) BVDV can cause early embryonic mortality. Upregulation of type I interferon stimulated genes (I... Read More about Acute BVDV infection inhibits expression of interferon-stimulated genes during pregnancy recognition in bovine endometrium.

Clinical presentation and outcome of dogs treated medically or surgically for thoracolumbar intervertebral disc protrusion (2017)
Journal Article
Crawford, A. H., & De Decker, S. (2017). Clinical presentation and outcome of dogs treated medically or surgically for thoracolumbar intervertebral disc protrusion. Veterinary Record, 180(23), https://doi.org/10.1136/vr.103871

To date, few studies have investigated the clinical characteristics of thoracolumbar intervertebral disc protrusion (IVDP). The aim of this retrospective study was to evaluate the presentation and outcome of dogs receiving medical or surgical treatme... Read More about Clinical presentation and outcome of dogs treated medically or surgically for thoracolumbar intervertebral disc protrusion.

Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus). (2017)
Journal Article
Messer, A. E., Chan, J., Daley, A., Copeland, O., Marston, S. B., & Connolly, D. J. (2017). Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus). Frontiers in Physiology, 8, 348. https://doi.org/10.3389/fphys.2017.00348

Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll. Hom... Read More about Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus)..

Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich (2017)
Journal Article
Chadwick, K., Shefelbine, S. J., Pitsillides, A. A., & Hutchinson, J. R. (2017). Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich. Royal Society Open Science, 4(6), 170133. https://doi.org/10.1098/rsos.170133

The appearance and shape of sesamoid bones within a tendon or ligament wrapping around a joint are understood to be influenced by both genetic and epigenetic factors. Ostriches (Struthio camelus) possess two sesamoid patellae (kneecaps), one of which... Read More about Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich.

A comparison of policies to reduce the methane emission intensity of smallholder dairy production in India (2017)
Journal Article
York, L., Heffernan, C., & Rymer, C. (2017). A comparison of policies to reduce the methane emission intensity of smallholder dairy production in India. https://doi.org/10.1016/j.agee.2017.05.032

Within the dairy sector, the effects of climate change are particularly diverse as cows are affected by, and a significant contributor to climate change. With a burgeoning body of work indicating the importance of livestock’s contribution to climate... Read More about A comparison of policies to reduce the methane emission intensity of smallholder dairy production in India.

A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells (2017)
Journal Article
Delaney, A. M., Adams, C. F., Fernandes, A. R., Al-Shakli, A. F., Sen, J., Carwardine, D. R., Granger, N., & Chari, D. M. (2017). A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells. Nanoscale, 9(25), 8560-8566. https://doi.org/10.1039/c7nr00811b

Olfactory ensheathing cells (OECs) promote axonal regeneration and improve locomotor function when transplanted into the injured spinal cord. A recent clinical trial demonstrated improved motor function in domestic dogs with spinal injury following a... Read More about A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells.

Policies and livestock systems driving brucellosis re-emergence in Kazakhstan (2017)
Journal Article
Beauvais, W., Coker, R., Nurtazina, G., & Guitian, J. (2017). Policies and livestock systems driving brucellosis re-emergence in Kazakhstan. EcoHealth, 14(2), 399-407. https://doi.org/10.1007/s10393-015-1030-7

Brucellosis is a considerable public health and economic burden in many areas of the world including sub-Saharan Africa, the Middle East and former USSR countries. The collapse of the USSR has been cited as a driver for re-emergence of diseases inclu... Read More about Policies and livestock systems driving brucellosis re-emergence in Kazakhstan.

Owner perceptions of their cat's quality of life when treated with a modified University of Wisconsin-Madison protocol for lymphoma (2017)
Journal Article
Thornton, L. A., Cave, N. J., Bridges, J. P., & Stell, A. J. (2017). Owner perceptions of their cat's quality of life when treated with a modified University of Wisconsin-Madison protocol for lymphoma. Journal of Feline Medicine and Surgery, 20(4), 356-361. https://doi.org/10.1177/1098612X17710844

The objectives of this study were to assess owner perceptions of their cat’s quality of life during treatment for lymphoma with a doxorubicin-containing multi-agent chemotherapy protocol, whether various health-related parameters correlated with qual... Read More about Owner perceptions of their cat's quality of life when treated with a modified University of Wisconsin-Madison protocol for lymphoma.

Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release (2017)
Journal Article
Orriss, I. R., Gueneri, D., Hajjawai, M. O., Shaw, K., Patel, J. J., & Arnett, T. R. (2017). Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release. Journal of Endocrinology, 233, 341-356. https://doi.org/10.1530/JOE-17-0042

Bone cells constitutively release ATP into the extracellular environment where it acts locally via P2 receptors to regulate bone cell function. Whilst P2Y2 receptor stimulation regulates bone mineralisation, the functional effects of this receptor in... Read More about Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release.