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All Outputs (395)

Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs (2019)
Journal Article
Pelander, L., Brunchault, V., Buffin-Meyer, B., Klein, J., Breuil, B., Zürbig, P., …Ljungvall, I. (2019). Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs. https://doi.org/10.1016/j.tvjl.2019.05.010

Chronic kidney disease (CKD) is clinically important in canine medicine. Current diagnostic tools lack sensitivity for detection of subclinical CKD. The aim of the present study was to evaluate urinary peptidome analysis for diagnosis of CKD in dogs.... Read More about Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs.

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts (2019)
Journal Article
Patel, J. J., Bourne, L. E., Davies, B. K., Arnett, T. R., MacRae, V. E., Wheeler-Jones, C. P. D., & Orriss, I. R. (2019). Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts. Experimental Cell Research, 380(1), 100-113. https://doi.org/10.1016/j.yexcr.2019.04.020

Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as hydroxyapatite, in the medial layer of the arteries. AMC shares some similarities to skeletal mineralisation and has been associated with the transdifferenti... Read More about Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts.

Sedative and antinociceptive effects of different detomidine constant rate infusions, with or without methadone in standing horses (2019)
Journal Article
Gozalo-Marcilla, M., Rodrigues De Oliveira, A., Werneck Fonseca, M., Possebon, F. S., Pelligand, L., Taylor, P. M., & Luna, S. P. L. (2019). Sedative and antinociceptive effects of different detomidine constant rate infusions, with or without methadone in standing horses. Equine Veterinary Journal, 51(4), 530-536. https://doi.org/10.1111/evj.13054

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases (2019)
Journal Article
Singhania, A., Graham, C. M., Gabryšová, L., Moreira-Teixeira, L., Stavropoulos, E., Pitt, J. M., …O’Garra, A. (2019). Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases. Nature Communications, 10, https://doi.org/10.1038/s41467-019-10601-6

Understanding how immune challenges elicit different responses is critical for diagnosing and deciphering immune regulation. Using a modular strategy to interpret the complex transcriptional host response in mouse models of infection and inflammation... Read More about Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Clinical reasoning in feline spinal disease: which combination of clinical information is useful? (2019)
Journal Article
Mella, S. L., Cardy, T. J. A., Volk, H. A., & De Decker, S. (2019). Clinical reasoning in feline spinal disease: which combination of clinical information is useful?. Journal of Feline Medicine and Surgery, https://doi.org/10.1177/1098612X19858447

The aim of this study was to evaluate if a combination of discrete clinical characteristics can be used to identify the most likely differential diagnoses in cats with spinal disease.

Managed trade: The US–Mexico sugar suspension agreements (2019)
Journal Article
Carter, C. A., Saitone, T. L., & Schaefer, K. A. (2019). Managed trade: The US–Mexico sugar suspension agreements. Canadian Journal of Economics, https://doi.org/10.1111/caje.12393

Under the 1994 North American Free Trade Agreement, Mexican sugar producers were ultimately granted free access to the US sugar market, while all other suppliers, including US refiners, were subject to supply quotas. Following a surge in imports of M... Read More about Managed trade: The US–Mexico sugar suspension agreements.

Pet owners' awareness of animal blood banks and their motivations towards animal blood donation (2019)
Journal Article
Wilder, A., & Humm, K. R. (2019). Pet owners' awareness of animal blood banks and their motivations towards animal blood donation. Veterinary Record, https://doi.org/10.1136/vr.105139

The general public’s awareness of, and attitude to, canine and feline blood donation is poorly understood. Increasing understanding of pet owners’ thoughts about donation may allow more effective blood donor recruitment. The aims of this study were t... Read More about Pet owners' awareness of animal blood banks and their motivations towards animal blood donation.

Physics of Animal Health: On the mechano-biology of hoof growth and form (2019)
Journal Article
Al-Agele, R., Paul, E., Taylor, S., Watson, C., Sturrock, C., Drakopoulos, M., …Rauch, C. (2019). Physics of Animal Health: On the mechano-biology of hoof growth and form. https://doi.org/10.1098/rsif.2019.0214

Global inequalities in economic access and agriculture productivity imply that a large number of developing countries rely on working equids for transport/agriculture/mining. Therefore, the understanding of hoof conditions/shape variations affecting... Read More about Physics of Animal Health: On the mechano-biology of hoof growth and form.

Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales (2019)
Journal Article
Wileman, T. M., Weinert, L. A., Howell, K. J., Wang, J., Peters, S. E., Williamson, S. M., …Tucker, A. W. (2019). Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales. Journal of Clinical Microbiology, 57, e01712. https://doi.org/10.1128/JCM.01712-18

Streptococcus suis is one of the most important zoonotic bacterial pathogens of pigs, causing significant economic losses to the global swine industry. S. suis is also a very successful colonizer of mucosal surfaces, and commensal strains can be foun... Read More about Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales.

A novel, high-sensitivity, bacteriophage-based assay identifies low level Mycobacterium tuberculosis bacteraemia in immunocompetent patients with active and incipient tuberculosis (2019)
Journal Article
Verma, R., Swift, B. M. C., Handley-Hartill, W., Lee, J. K., Woltmann, G., Rees, C. E. D., & Haldar, P. (2019). A novel, high-sensitivity, bacteriophage-based assay identifies low level Mycobacterium tuberculosis bacteraemia in immunocompetent patients with active and incipient tuberculosis. Clinical Infectious Diseases, 70(5), 933-936. https://doi.org/10.1093/cid/ciz548

Haematogenous dissemination of M. tuberculosis (Mtb) is critical to pathogenesis of progressive tuberculous infection in animal models. Using a novel phage-based blood assay, we report the first concordant evidence in well-characterised immunocompete... Read More about A novel, high-sensitivity, bacteriophage-based assay identifies low level Mycobacterium tuberculosis bacteraemia in immunocompetent patients with active and incipient tuberculosis.

Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome (2019)
Journal Article
Pittaway, R., Dobromylskyj, M. J., Erles, K., Pittaway, C. E., Suárez-Bonnet, A., Chang, Y. M., & Priestnall, S. L. (2019). Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome. Veterinary Pathology, 56(6), 868-877. https://doi.org/10.1177/0300985819854435

Nonocular melanocytic neoplasia is considered uncommon in cats yet is routinely encountered in diagnostic pathology and recognized to exhibit a wide variation in biological behavior. Accurate prediction of clinical outcomes is challenging with no wid... Read More about Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome.

Retrospective evaluation of the clinical presentation, magnetic resonance imaging findings, and outcome of dogs diagnosed with intracranial empyema (2008–2015): 9 cases (2019)
Journal Article
Forward, A. K., Plessas, I. N., Guilherme, S., & De Decker, S. (2019). Retrospective evaluation of the clinical presentation, magnetic resonance imaging findings, and outcome of dogs diagnosed with intracranial empyema (2008–2015): 9 cases. Journal of Veterinary Emergency and Critical Care, 29(4), 431-438. https://doi.org/10.1111/vec.12859

Retrospective evaluation of the association between admission blood glucose and l-lactate concentrations in ponies and horses with gastrointestinal disease (2008-2016): 545 cases (2019)
Journal Article
Dunkel, B., Mason, C. J., & Chang, Y. M. (2019). Retrospective evaluation of the association between admission blood glucose and l-lactate concentrations in ponies and horses with gastrointestinal disease (2008-2016): 545 cases. Journal of Veterinary Emergency and Critical Care, https://doi.org/10.1111/vec.12851

A recent study described increased l‐lactate concentrations in ponies with gastrointestinal disease compared to horses, but blood glucose (BG) concentrations were not considered. The study tested the hypothesis that BG and l‐lactate concentrations ar... Read More about Retrospective evaluation of the association between admission blood glucose and l-lactate concentrations in ponies and horses with gastrointestinal disease (2008-2016): 545 cases.

Opportunistic bacteria and mass mortality in ungulates: lessons from an extreme event (2019)
Journal Article
Robinson, S., Milner-Gulland, E. J., Grachev, Y., Salemgareyev, A., Orynbayev, M., Morgan, E., …Kock, R. A. (2019). Opportunistic bacteria and mass mortality in ungulates: lessons from an extreme event. Ecosphere, 10(6), e02671. https://doi.org/10.1002/ecs2.2671

Mass mortality events in wildlife are a growing concern. Under conditions of rapid global change, opportunistic responses in bacterial commensals, triggered by environmental stressors, may be increasingly implicated in die‐offs. In 2015, over 200,000... Read More about Opportunistic bacteria and mass mortality in ungulates: lessons from an extreme event.

Targeting Drp1 and mitochondrial fission for therapeutic immune modulation (2019)
Journal Article
Simula, L., Campanella, M., & Campello, S. (2019). Targeting Drp1 and mitochondrial fission for therapeutic immune modulation. Pharmacological Research, 146, https://doi.org/10.1016/j.phrs.2019.104317

Mitochondria are dynamic organelles whose processes of fusion and fission are tightly regulated by specialized proteins, known as mitochondria-shaping proteins. Among them, Drp1 is the main pro-fission protein and its activity is tightly regulated to... Read More about Targeting Drp1 and mitochondrial fission for therapeutic immune modulation.

A preliminary study assessing cytokine production following ex vivo stimulation of whole blood with diet in dogs with chronic enteropathy (2019)
Journal Article
Kathrani, A., & Hall, E. (2019). A preliminary study assessing cytokine production following ex vivo stimulation of whole blood with diet in dogs with chronic enteropathy. BMC Veterinary Research, 15(185), https://doi.org/10.1186/s12917-019-1940-7

Ex vivo whole blood stimulation assays (WBSA) have been used to characterize the cytokine response to diet in cats. The present study aimed to use this assay to determine the cytokine response to diets being fed at the time of diagnosis to dogs with... Read More about A preliminary study assessing cytokine production following ex vivo stimulation of whole blood with diet in dogs with chronic enteropathy.