Skip to main content

Research Repository

Advanced Search

All Outputs (417)

Reverse-engineering the locomotion of a stem amniote (2019)
Journal Article
Nyakatura, J. A., Melo, K., Horvat, T., Karakasiliotis, K., Allen, V. R., Andikfar, A., …Ijspeert, A. J. (2019). Reverse-engineering the locomotion of a stem amniote. Nature, 565, 351-355. https://doi.org/10.1038/s41586-018-0851-2

Reconstructing the locomotion of extinct vertebrates offers insights into their palaeobiology and helps to conceptualize major transitions in vertebrate evolution. However, estimating the locomotor behaviour of a fossil species remains a challenge be... Read More about Reverse-engineering the locomotion of a stem amniote.

American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational use of Antithrombotics in Veterinary Critical Care (CURATIVE) Guidelines: Small Animal (2019)
Journal Article
Goggs, R., Blais, M., Brainard, B. M., Chan, D. L., DeLaforcade, A. M., Rozanski, E., & Sharp, C. R. (2019). American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational use of Antithrombotics in Veterinary Critical Care (CURATIVE) Guidelines: Small Animal. Journal of Veterinary Emergency and Critical Care, 29(1), 12-36. https://doi.org/10.1111/vec.12801

Rapidly assessing the risks of infectious diseases to wildlife species (2019)
Journal Article
Beauvais, W., Zuther, S., Villeneuve, C., Kock, R. A., & Guitian, J. (2019). Rapidly assessing the risks of infectious diseases to wildlife species. Royal Society Open Science, 6(1), https://doi.org/10.1098/rsos.181043

Predicting the likelihood of rare events is increasingly demanded by risk managers. A key challenge is dealing with different types of uncertainty, including epistemic uncertainties (lack of knowledge), stochasticity (inherent randomness) and natural... Read More about Rapidly assessing the risks of infectious diseases to wildlife species.

Lead intoxication mimicking idiopathic epilepsy in a young dog (2019)
Journal Article
Liatis, T., Monti, P., Latre, A. R., Mantis, P., & Cherubini, G. B. (2019). Lead intoxication mimicking idiopathic epilepsy in a young dog. Vet Record Case Reports, 7(1), https://doi.org/10.1136/vetreccr-2018-000703

An 11-month-old neutered female cocker spaniel was referred for two generalised tonic-clonic epileptic seizures with a one-week interval of mild depression. On admission, physical and neurological examinations were unremarkable. Neurolocalisation was... Read More about Lead intoxication mimicking idiopathic epilepsy in a young dog.

Pilot study of head conformation changes over time in the Cavalier King Charles spaniel breed (2019)
Journal Article
Knowler, S. P., Gillstedt, L., Mitchell, T. J., Jovanovik, J., Volk, H. A., & Rusbridge, C. (2019). Pilot study of head conformation changes over time in the Cavalier King Charles spaniel breed. Veterinary Record, 184(4), https://doi.org/10.1136/vr.105135

Modern interpretation of head conformation in the Cavalier King Charles spaniel (CKCS) has favoured a smaller, more exaggerated, brachycephalic type than originally described in the 1929 breed standard. Recent research studies identified brachycephal... Read More about Pilot study of head conformation changes over time in the Cavalier King Charles spaniel breed.

Structural characteristics and predicted functional capacities of epaxial muscles in chondrodystrophic and non-chondrodystrophic dogs with and without suspected intervertebral disc herniation- a preliminary study (2019)
Journal Article
Boström, A., Channon, S. B., Jokinen, T. S., Junnila, J., Hielm-Bjorkman, A. K., & Laitinen-Vapaavuori, O. (2019). Structural characteristics and predicted functional capacities of epaxial muscles in chondrodystrophic and non-chondrodystrophic dogs with and without suspected intervertebral disc herniation- a preliminary study. Research in Veterinary Science, 123, 204-215. https://doi.org/10.1016/j.rvsc.2019.01.008

Epaxial muscle atrophy is related to spinal diseases in dogs. However, the influence of intervertebral disc herniation (IVDH) on the functional capacity of epaxial muscles has not been investigated. We aimed to estimate force and power-generating cap... Read More about Structural characteristics and predicted functional capacities of epaxial muscles in chondrodystrophic and non-chondrodystrophic dogs with and without suspected intervertebral disc herniation- a preliminary study.

Pharmacokinetics of an intravenous and oral dose of enrofloxacin in white rhinoceros (Ceratotherium simum) (2019)
Journal Article
Leiberich, M., Krebber, R., Hewetson, M., Marais, J., & Naidoo, V. (2019). Pharmacokinetics of an intravenous and oral dose of enrofloxacin in white rhinoceros (Ceratotherium simum). Journal of Veterinary Pharmacology and Therapeutics, 42(3), 346-354. https://doi.org/10.1111/jvp.12747

South Africa currently loses over 1000 white rhinoceros (Ceratotherium simum) each year to poaching incidents, and numbers of severely injured victims found alive have increased dramatically. However, little is known about the antimicrobial treatment... Read More about Pharmacokinetics of an intravenous and oral dose of enrofloxacin in white rhinoceros (Ceratotherium simum).

On-farm pig dispatch methods employed in Brazil and stockpeople attitudes on their use (2019)
Journal Article
Dalla Costa, F. A., Gibson, T. J., Octavio Oliveira, S. E., Gregory, N. G., Coldebella, A., Faucitano, L., & Dalla Costa, O. A. (2019). On-farm pig dispatch methods employed in Brazil and stockpeople attitudes on their use. Livestock Science, 221, https://doi.org/10.1016/j.livsci.2019.01.007

This study surveyed the on-farm dispatching methods used at pig farms, the characteristics of stockpeople operating them, in terms of training and management, and their opinions and attitudes about the efficiency and safety of the applied procedures.... Read More about On-farm pig dispatch methods employed in Brazil and stockpeople attitudes on their use.

CXCR4 Antagonism to Treat Delayed Fracture Healing (2019)
Journal Article
Meeson, R. L., Sanghani, A., Coathup, M., & Blunn, G. (2019). CXCR4 Antagonism to Treat Delayed Fracture Healing. https://doi.org/10.1089/ten.TEA.2018.0265

A significant number of fractures develop non-union. Stem cell homing is regulated through SDF-1 and its receptor CXCR4. Stem/progenitor cell populations can be endogenously mobilised by administering growth factors with a pharmacological antagonist... Read More about CXCR4 Antagonism to Treat Delayed Fracture Healing.

Plasticity of Amino Acid Residue 145 Near the Receptor Binding Site of H3 Swine Influenza A Viruses and Its Impact on Receptor Binding and Antibody Recognition (2019)
Journal Article
Santos, J. J. S., Abente, E. J., Obadan, A. O., Thompson, A. J., Ferreri, L., Geiger, G., …Perez, D. R. (2019). Plasticity of Amino Acid Residue 145 Near the Receptor Binding Site of H3 Swine Influenza A Viruses and Its Impact on Receptor Binding and Antibody Recognition. Journal of Virology, 93(2), e01413-18. https://doi.org/10.1128/JVI.01413-18

The hemagglutinin (HA), a glycoprotein on the surface of influenza A virus (IAV), initiates the virus life cycle by binding to terminal sialic acid (SA) residues on host cells. The HA gradually accumulates amino acid substitutions that allow IAV to e... Read More about Plasticity of Amino Acid Residue 145 Near the Receptor Binding Site of H3 Swine Influenza A Viruses and Its Impact on Receptor Binding and Antibody Recognition.

GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice (2019)
Journal Article
Puig, B., Altmeppen, H. C., Linsenmeier, L., Chakroun, K., Wegwitz, F., Piontek, U. K., …Glatzel, M. (2019). GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice. PLoS Pathogens, 15(1), e1007520. https://doi.org/10.1371/journal.ppat.1007520

The cellular prion protein (PrPC) is a cell surface glycoprotein attached to the membrane by a glycosylphosphatidylinositol (GPI)-anchor and plays a critical role in transmissible, neurodegenerative and fatal prion diseases. Alterations in membrane a... Read More about GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice.

Genome reconstruction of a novel carbohydrate digesting bacterium from the chicken caecal microflora (2019)
Journal Article
Hinsu, A. T., Pandit, R. J., Patel, S. H., Psifidi, A., Tomley, F. M., Das, S. K., …Joshi, C. G. (2019). Genome reconstruction of a novel carbohydrate digesting bacterium from the chicken caecal microflora. https://doi.org/10.1016/j.mgene.2019.01.002

The advent of metagenomics using Next-Generation Sequencing (NGS) has led to the acquisition of unprecedented quantities of bacterial sequence data. One use for these data is the recovery of complete genomes of uncultivable, and thus uncharacterised,... Read More about Genome reconstruction of a novel carbohydrate digesting bacterium from the chicken caecal microflora.

Association between Single Nucleotide Polymorphism in RelA with Somatic Cell Count and Longevity Supports Importance of NF-¦ÊB Signalling in Cattle Health (2019)
Journal Article
Chen, X., Zhang, S., Cheng, Z. R., Pollott, G. E., & Wathes, D. C. (2019). Association between Single Nucleotide Polymorphism in RelA with Somatic Cell Count and Longevity Supports Importance of NF-¦ÊB Signalling in Cattle Health. Open Journal of Animal Sciences, 9(1), 51-64. https://doi.org/10.4236/ojas.2019.91005

Mastitis reduces milk production and causes culling. The NF-κB transcription factor RelA plays a central regulatory role in innate immunity. This study used a candidate gene approach to investigate associations between the synonymous C/G SNP rs480357... Read More about Association between Single Nucleotide Polymorphism in RelA with Somatic Cell Count and Longevity Supports Importance of NF-¦ÊB Signalling in Cattle Health.

Practical approaches to animal health issues on organic farms (2019)
Journal Article
Plate, P. (2019). Practical approaches to animal health issues on organic farms. Livestock, 24(1), 34-40. https://doi.org/10.12968/live.2019.24.1.34

A summary of a workshop attended by 15 delegates at the BCVA congress on 19th October 2018. The workshop started with an overview of organic animal health standards and the organic market. In the EU animal health standards promote ‘positive health’... Read More about Practical approaches to animal health issues on organic farms.

The respiratory mechanics of the yacare caiman (Caiman yacare Daudine) (2019)
Journal Article
Reichert, M. N., De Oliveira, P. R. C., Souza, G. M. P. R., Moranza, H. G., Restan, W. A. Z., Abe, A. S., …Milsom, W. K. (2019). The respiratory mechanics of the yacare caiman (Caiman yacare Daudine). Journal of Experimental Biology, 222(2), https://doi.org/10.1242/jeb.193037

The structure and function of crocodilian lungs are unique compared to other reptiles. We examine the extent to which this, and the semi-aquatic lifestyle of crocodilians affect their respiratory mechanics. We measured changes in intratracheal pressu... Read More about The respiratory mechanics of the yacare caiman (Caiman yacare Daudine).

The locomotor kinematics and ground reaction forces of walking giraffes. (2019)
Journal Article
Basu, C. K., Wilson, A. M., & Hutchinson, J. R. (2019). The locomotor kinematics and ground reaction forces of walking giraffes. Journal of Experimental Biology, 222(22), https://doi.org/10.1242/jeb.159277

Giraffes (Giraffa camelopardalis Linnaeus 1758) possess specialised anatomy. Their disproportionately elongate limbs and neck confer recognised feeding advantages, but little is known about how their morphology affects locomotor function. In this stu... Read More about The locomotor kinematics and ground reaction forces of walking giraffes..

Pituitary pathology and gene expression in acromegalic cats (2019)
Journal Article
Scudder, C. J., Mirczuk, S. M., Richardson, K. M., Crossley, V. J., Regan, J. T. C., Gostelow, R., …Niessen, S. J. M. (2019). Pituitary pathology and gene expression in acromegalic cats. Journal of the Endocrine Society, 3(1), 181-200. https://doi.org/10.1210/js.2018-00226

The prevalence of growth hormone secreting pituitary tumours in domestic cats (Felis catus) is ten times greater than in humans. The predominant inhibitory receptors of growth hormone-secreting pituitary tumours are somatostatin receptors (SSTRs) and... Read More about Pituitary pathology and gene expression in acromegalic cats.