Epidemiology of Dog Bite Incidents in Chile: Factors Related to the Patterns of Human-Dog Relationship

Barrios, CL; Bustos-Lopez, C; Pavletic, C; Parra, A; Vidal, M; Bowen, J; Fatjo, J

doi:10.3390/ani11010096

Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses (2021)
Journal Article
Kuroda, T., Minamijima, Y., Niwa, H., Tamura, N., Mita, H., Fukuda, K., …Kasashima, Y. (2021). Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses. Equine Veterinary Journal, 53(6), 1239-1249. https://doi.org/10.1111/evj.13406

Background: First-generation cephalosporins have good activity against gram-positive bacteria and are extensively used in horses. There are few reports of pharmacokinetics and pharmacodynamics (PK/PD) analysis of cephalosporins in horses. Objective:... Read More about Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses.

Kinetic disposition of diazepam and its metabolites after intravenous administration of diazepam in the horse: Relevance for doping control (2021)
Journal Article
Schenk, I., Machnik, M., Broussou, D., Meuly, A., Roques, B., Lallemand, E., …Thevis, M. (2021). Kinetic disposition of diazepam and its metabolites after intravenous administration of diazepam in the horse: Relevance for doping control. Journal of Veterinary Pharmacology and Therapeutics, 44(5), 733-744. https://doi.org/10.1111/jvp.12991

In horses, the benzodiazepine diazepam (DIA) is used as sedative for pre-medication or as an anxiolytic to facilitate horse examinations. As the sedative effects can also be abused for doping purposes, DIA is prohibited in equine sports. DIA is exten... Read More about Kinetic disposition of diazepam and its metabolites after intravenous administration of diazepam in the horse: Relevance for doping control.

Genetic and Antigenic Characterization of Avian Avulavirus Type 6 (AAvV-6) Circulating in Canadian Wild Birds (2005-2017) (2021)
Journal Article
Hisanaga, T., Soos, C., Lewis, N., Lung, O., Suderman, M., & Berhane, Y. (2021). Genetic and Antigenic Characterization of Avian Avulavirus Type 6 (AAvV-6) Circulating in Canadian Wild Birds (2005-2017). Viruses, 13(4), https://doi.org/10.3390/v13040543

We describe for the first time the genetic and antigenic characterization of 18 avian avulavirus type-6 viruses (AAvV-6) that were isolated from wild waterfowl in the Americas over the span of 12 years. Only one of the AAvV-6 viruses isolated failed... Read More about Genetic and Antigenic Characterization of Avian Avulavirus Type 6 (AAvV-6) Circulating in Canadian Wild Birds (2005-2017).

Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion (2021)
Journal Article
Schlott, A., Knuepfer, E., Green, J., Hobson, P., Borg, A., Morales-Sanfrutos, J., …Holder, A. (2021). Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion. PLoS Biology, 19(10), https://doi.org/10.1371/journal.pbio.3001408

We have combined chemical biology and genetic modification approaches to investigate the importance of protein myristoylation in the human malaria parasite, Plasmodium falciparum. Parasite treatment during schizogony in the last 10 to 15 hours of the... Read More about Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion.

Clinical features and outcome of acquired myasthenia gravis in 94 dogs (2021)
Journal Article
Forgash, J., Chang, Y., Mittelman, N., Petesch, S., Benedicenti, L., Galban, E., …Garden, O. (2021). Clinical features and outcome of acquired myasthenia gravis in 94 dogs. Journal of Veterinary Internal Medicine, 35(5), 2315-2326. https://doi.org/10.1111/jvim.16223

Background Factors known to be associated with outcome of acquired myasthenia gravis (MG) in dogs are limited. Hypothesis/Objectives Of dogs with MG, advancing age and comorbid neoplasia are associated with poor long-term prognosis and low rates of r... Read More about Clinical features and outcome of acquired myasthenia gravis in 94 dogs.

Continuing professional development for veterinarians in a changing world (2021)
Journal Article
Wieland, B., Daborn, C., Debnath, N., & Silva-Fletcher, A. (2021). Continuing professional development for veterinarians in a changing world. Scientific & Technical Review, 40(2), 555-566. https://doi.org/10.20506/rst.40.2.3245

The veterinary profession has time and again successfully adapted to new challenges and developments, with considerable evolution of the skills needed. Different contexts, production systems and societal requirements continue to shape the profession,... Read More about Continuing professional development for veterinarians in a changing world.

Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor (2021)
Journal Article
Tan, M., Koussis, K., Withers-Martinez, C., Howell, S., Thomas, J., Hackett, F., …Blackman, M. (2021). Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor. EMBO Journal, 40(11), https://doi.org/10.15252/embj.2020107226

Malaria parasite egress from host erythrocytes (RBCs) is regulated by discharge of a parasite serine protease called SUB1 into the parasitophorous vacuole (PV). There, SUB1 activates a PV-resident cysteine protease called SERA6, enabling host RBC rup... Read More about Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor.

Scaling-Down Mass Ivermectin Treatment for Onchocerciasis Elimination: Modeling the Impact of the Geographical Unit for Decision Making (2021)
Journal Article
Stolk, W., Blok, D., Hamley, J., Cantey, P., de Vlas, S., Walker, M., & Basanez, M. (2021). Scaling-Down Mass Ivermectin Treatment for Onchocerciasis Elimination: Modeling the Impact of the Geographical Unit for Decision Making. Clinical Infectious Diseases, 72, S165-S171. https://doi.org/10.1093/cid/ciab238

Background. Due to spatial heterogeneity in onchocerciasis transmission, the duration of ivermectin mass drug administration (MDA) required for eliminating onchocerciasis will vary within endemic areas and the occurrence of transmission "hotspots" is... Read More about Scaling-Down Mass Ivermectin Treatment for Onchocerciasis Elimination: Modeling the Impact of the Geographical Unit for Decision Making.

Immune Response in Mice Immunized with Chimeric H1 Antigens (2021)
Journal Article
Kotey, E., Ampofo, W., Daines, R., Sadeyen, J., Iqbal, M., & Quaye, O. (2021). Immune Response in Mice Immunized with Chimeric H1 Antigens. Vaccines, 9(10), https://doi.org/10.3390/vaccines9101182

Identification of a universal influenza vaccine candidate has remained a global challenge for both humans and animals. This study describes an approach that uses consensus sequence building to generate chimeric HAs (cHAs): two resultant H1 HA-based c... Read More about Immune Response in Mice Immunized with Chimeric H1 Antigens.

Focused ultrasound of the caudal vena cava in dogs with cavitary effusions or congestive heart failure: A prospective, observational study (2021)
Journal Article
Chou, Y., Ward, J., Barron, L., Murphy, S., Tropf, M., Lisciandro, G., …DeFrancesco, T. (2021). Focused ultrasound of the caudal vena cava in dogs with cavitary effusions or congestive heart failure: A prospective, observational study. PLoS ONE, 16(5), https://doi.org/10.1371/journal.pone.0252544

Introduction Ultrasonographic indices of the inferior vena cava are useful for predicting right heart filling pressures in people. Objectives To determine whether ultrasonographic indices of caudal vena cava (CVC) differ between dogs with right-sided... Read More about Focused ultrasound of the caudal vena cava in dogs with cavitary effusions or congestive heart failure: A prospective, observational study.

The risk of pancreatic adenocarcinoma following SARS-CoV family infection (2021)
Journal Article
Sadrabadi, A., Bereimipour, A., Jalili, A., Gholipurmalekabadi, M., Farhadihosseinabadi, B., & Seifalian, A. (2021). The risk of pancreatic adenocarcinoma following SARS-CoV family infection. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-92068-4

COVID 19 disease has become a global catastrophe over the past year that has claimed the lives of over two million people around the world. Despite the introduction of vaccines against the disease, there is still a long way to completely eradicate it... Read More about The risk of pancreatic adenocarcinoma following SARS-CoV family infection.

Longitudinal Secretion of Paramyxovirus RNA in the Urine of Straw-Coloured Fruit Bats (Eidolon helvum) (2021)
Journal Article
Jolma, E., Gibson, L., Suu-Ire, R., Fleischer, G., Asumah, S., Languon, S., …Cunningham, A. (2021). Longitudinal Secretion of Paramyxovirus RNA in the Urine of Straw-Coloured Fruit Bats (Eidolon helvum). Viruses, 13(8), https://doi.org/10.3390/v13081654

The straw-coloured fruit bat (Eidolon helvum) is widespread in sub-Saharan Africa and is widely hunted for bushmeat. It is known to harbour a range of paramyxoviruses, including rubuloviruses and henipaviruses, but the zoonotic potential of these is... Read More about Longitudinal Secretion of Paramyxovirus RNA in the Urine of Straw-Coloured Fruit Bats (Eidolon helvum).

Evolution of forelimb musculoskeletal function across the fish-to-tetrapod transition (2021)
Journal Article
Molnar, J., Hutchinson, J., Diogo, R., Clack, J., & Pierce, S. (2021). Evolution of forelimb musculoskeletal function across the fish-to-tetrapod transition. Science Advances, 7(4), https://doi.org/10.1126/sciadv.abd7457

One of the most intriguing questions in vertebrate evolution is how tetrapods gained the ability to walk on land. Although many hypotheses have been proposed, few have been rigorously tested using the fossil record. Here, we build three-dimensional m... Read More about Evolution of forelimb musculoskeletal function across the fish-to-tetrapod transition.

What does the COVID-19 pandemic mean for the next decade of onchocerciasis control and elimination? (2021)
Journal Article
Hamley, J., Blok, D., Walker, M., Milton, P., Hopkins, A., Hamill, L., …Basanez, M. (2021). What does the COVID-19 pandemic mean for the next decade of onchocerciasis control and elimination?. Transactions of the Royal Society of Tropical Medicine & Hygiene, 115(3), 269-280. https://doi.org/10.1093/trstmh/traa193

Background: Mass drug administration (MDA) of ivermectin for onchocerciasis has been disrupted by the coronavirus disease 2019 (COVID-19) pandemic. Mathematical modelling can help predict how missed/delayed MDA will affect short-term epidemiological... Read More about What does the COVID-19 pandemic mean for the next decade of onchocerciasis control and elimination?.

In Vitro Supplementation of Copper Modulates the Functional Th1/Th2 Phenotype of Peripheral Blood Mononuclear Cells in Cattle (2021)
Journal Article
Bunting, M., Challice, B., & van Winden, S. (2021). In Vitro Supplementation of Copper Modulates the Functional Th1/Th2 Phenotype of Peripheral Blood Mononuclear Cells in Cattle. Animals, 11(9), https://doi.org/10.3390/ani11092739

Simple Summary This study investigated the association of copper levels and the appearance of blood monocytes, a white blood cell. One type of monocytes (M1) supports cellular immunity and the M2 monocyte helps the immune system through antibodies. F... Read More about In Vitro Supplementation of Copper Modulates the Functional Th1/Th2 Phenotype of Peripheral Blood Mononuclear Cells in Cattle.

Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics in mouse embryos (2021)
Journal Article
Maniou, E., Staddon, M., Marshall, A., Greene, N., Copp, A., Banerjee, S., & Galea, G. (2021). Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics in mouse embryos. Proceedings of the National Academy of Sciences, 118(19), https://doi.org/10.1073/pnas.2023163118

Gap closure is a common morphogenetic process. In mammals, failure to close the embryonic hindbrain neuropore (HNP) gap causes fatal anencephaly. We observed that surface ectoderm cells surrounding the mouse HNP assemble high-tension actomyosin purse... Read More about Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics in mouse embryos.

The regulation of healthcare professions and support workers in international context (2021)
Journal Article
Saks, M. (2021). The regulation of healthcare professions and support workers in international context. Human Resources for Health, 19(1), https://doi.org/10.1186/s12960-021-00618-8

Background The objective of this paper is to outline and compare the regulation of paid healthcare professions and associated support workers in international context, bringing out the lessons to be learned as appropriate. Modern neo-liberal societie... Read More about The regulation of healthcare professions and support workers in international context.

Complex trauma and its relation to hope and hopelessness among young people in KwaZulu-Natal, South Africa (2021)
Journal Article
Ngwenya, N., Barnett, T., Groenewald, C., & Seeley, J. (2021). Complex trauma and its relation to hope and hopelessness among young people in KwaZulu-Natal, South Africa. Vulnerable Children and Youth Studies, 16(2), 166-177. https://doi.org/10.1080/17450128.2020.1865593

Informed by an existing hope scale, we explored the roles of hope, happiness, and life satisfaction in adolescent risk behaviours in rural KwaZulu-Natal, South Africa, a setting with high HIV prevalence. In 2016 data were collected from two resource-... Read More about Complex trauma and its relation to hope and hopelessness among young people in KwaZulu-Natal, South Africa.

Discriminating lineages of Batrachochytrium dendrobatidis using quantitative PCR (2021)
Journal Article
Ghosh, P., Verster, R., Sewell, T., O'Hanlon, S., Brookes, L., Rieux, A., …Fisher, M. (2021). Discriminating lineages of Batrachochytrium dendrobatidis using quantitative PCR. Molecular Ecology Resources, 21(5), 1452-1459. https://doi.org/10.1111/1755-0998.13299

The ability to detect and monitor infectious disease in a phylogenetically informative manner is critical for their management. Phylogenetically informative diagnostic tests enable patterns of pathogen introduction or changes in the distribution of g... Read More about Discriminating lineages of Batrachochytrium dendrobatidis using quantitative PCR.

Epidemiology of Dog Bite Incidents in Chile: Factors Related to the Patterns of Human-Dog Relationship (2021)
Journal Article
Barrios, C., Bustos-Lopez, C., Pavletic, C., Parra, A., Vidal, M., Bowen, J., & Fatjo, J. (2021). Epidemiology of Dog Bite Incidents in Chile: Factors Related to the Patterns of Human-Dog Relationship. Animals, 11(1), https://doi.org/10.3390/ani11010096

Simple Summary Dog bites are a major public health problem throughout the world. The main consequences for human health include physical and psychological injuries of varying proportions, secondary infections, sequelae, risk of transmission of zoonos... Read More about Epidemiology of Dog Bite Incidents in Chile: Factors Related to the Patterns of Human-Dog Relationship.

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