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All Outputs (326)

Mechanosignalling pathways that regulate endothelial barrier function (2023)
Journal Article
McQueen, A., & Warboys, C. M. (2023). Mechanosignalling pathways that regulate endothelial barrier function. Current Opinion in Cell Biology, 84, 102213. https://doi.org/10.1016/j.ceb.2023.102213

Blood vessels are lined by a single layer of endothelial cells that provide a barrier between circulating plasma and the underlying tissue. Permeability of endothelial cells is tightly regulated, and increased permeability is associated with a number... Read More about Mechanosignalling pathways that regulate endothelial barrier function.

MicroRNAs Regulate Ca2+ Homeostasis in Murine Embryonic Stem Cells (2023)
Journal Article
Reid, K. M., Sanchez-Nieto, J. M., Terrasse, S., Faccenda, D., Pernaute, B., Campanella, M., …Cobb, B. S. (2023). MicroRNAs Regulate Ca2+ Homeostasis in Murine Embryonic Stem Cells. Cells, 12(15), 1957. https://doi.org/10.3390/cells12151957

MicroRNAs (miRNAs) are important regulators of embryonic stem cell (ESC) biology, and their study has identified key regulatory mechanisms. To find novel pathways regulated by miRNAs in ESCs, we undertook a bioinformatics analysis of gene pathways di... Read More about MicroRNAs Regulate Ca2+ Homeostasis in Murine Embryonic Stem Cells.

Canine insulinomas and their presumed metastases are most conspicuous in the late arterial phase in a triple arterial phase CT protocol (2023)
Journal Article
Skarbek, A., Fouriez-Lablée, V., Dirrig, H., & Llabres-Diaz, F. (2023). Canine insulinomas and their presumed metastases are most conspicuous in the late arterial phase in a triple arterial phase CT protocol. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13278

Avid arterial enhancement is the commonly described characteristic of canine insulinomas in contrast-enhanced computed tomography (CECT). However, this finding is also reported as inconsistent. The main aim of this study was to investigate in detai... Read More about Canine insulinomas and their presumed metastases are most conspicuous in the late arterial phase in a triple arterial phase CT protocol.

Ear health and quality of life in pet rabbits of differing ear conformations: a UK questionnaire survey of signalment risk factors and effects on rabbit welfare and behaviour (2023)
Journal Article
Chivers, B., Keeler, M., & Burn, C. (2023). Ear health and quality of life in pet rabbits of differing ear conformations: a UK questionnaire survey of signalment risk factors and effects on rabbit welfare and behaviour. PLoS ONE, https://doi.org/10.1371/journal.pone.0285372

The impacts of ear disease on animal welfare and behaviour are little documented. Ear disease may be common in rabbits, but difficult to recognise, and lop-ears have previously been indicated as a risk factor for ear disease. We aimed to better under... Read More about Ear health and quality of life in pet rabbits of differing ear conformations: a UK questionnaire survey of signalment risk factors and effects on rabbit welfare and behaviour.

Influence of the concentrate inclusion level in a grass silage-based diet on hepatic transcriptomic profiles in Holstein-Friesian dairy cows in early lactation (2023)
Journal Article
Cheng, Z., Little, M., Ferris, C., Takeda, H., Ingvartsen, K., Crowe, M., & Wathes, D. C. (2023). Influence of the concentrate inclusion level in a grass silage-based diet on hepatic transcriptomic profiles in Holstein-Friesian dairy cows in early lactation. Journal of Dairy Science, https://doi.org/10.3168/jds.2022-22860

Excessive negative energy balance (NEB) in early lactation is linked to an increased disease risk but may be mitigated by appropriate nutrition. The liver plays central roles in both metabolism and immunity. Hepatic transcriptomic profiles were compa... Read More about Influence of the concentrate inclusion level in a grass silage-based diet on hepatic transcriptomic profiles in Holstein-Friesian dairy cows in early lactation.

Assessing primary care veterinarians' use of and confidence in performing point-of-care ultrasound (2023)
Journal Article
McDonald, C., Barfield, D., & Cole, L. (2023). Assessing primary care veterinarians' use of and confidence in performing point-of-care ultrasound. Veterinary Record, https://doi.org/10.1002/vetr.3174

BackgroundPoint-of-care ultrasound (POCUS) is gaining popularity in the veterinary field, but there is little information on operator confidence. MethodsA survey was distributed to primary care veterinarians (PCVs) via social media between May and Ju... Read More about Assessing primary care veterinarians' use of and confidence in performing point-of-care ultrasound.

A Comparison of Dry Period Outcomes after Selective Dry Cow Therapy Carried out by Farm Staff versus Veterinary Students in a Low-Cell-Count Dairy Herd (2023)
Journal Article
Plate, P., & van Winden, S. (2023). A Comparison of Dry Period Outcomes after Selective Dry Cow Therapy Carried out by Farm Staff versus Veterinary Students in a Low-Cell-Count Dairy Herd. Animals, 13, https://doi.org/10.3390/ani13142318

(1) Background: Selective dry cow therapy is widely promoted in many countries worldwide, however, concerns have been raised about the consequences of the unhygienic application of preparations by untrained operators, especially if no antimicrobial... Read More about A Comparison of Dry Period Outcomes after Selective Dry Cow Therapy Carried out by Farm Staff versus Veterinary Students in a Low-Cell-Count Dairy Herd.

Survey of factors affecting satisfaction and success of residents enrolled in European College of Veterinary Diagnostic Imaging (ECVDI) residency programs (2023)
Journal Article
White, C., Maddox, T., & Mortier, J. (2023). Survey of factors affecting satisfaction and success of residents enrolled in European College of Veterinary Diagnostic Imaging (ECVDI) residency programs. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13275

Several published studies have described the success and satisfaction of residents enrolled in human radiology training programs, however comparable studies for veterinary radiology residents are currently lacking. The purpose of this descriptive, su... Read More about Survey of factors affecting satisfaction and success of residents enrolled in European College of Veterinary Diagnostic Imaging (ECVDI) residency programs.

Technical note: Cartilage imaging with sub-cellular resolution using a laboratory-based phase-contrast x-ray microscope (2023)
Journal Article
Esposito, M., Astolfo, A., Cipiccia, S., Jones, C., Savvidis, S., Ferrara, J., …Olivo, A. (2023). Technical note: Cartilage imaging with sub-cellular resolution using a laboratory-based phase-contrast x-ray microscope. Medical Physics, https://doi.org/10.1002/mp.16599

BackgroundMicroscopic imaging of cartilage is a key tool for the study and development of treatments for osteoarthritis. When cellular and sub-cellular resolution is required, histology remains the gold standard approach, albeit limited by the lack o... Read More about Technical note: Cartilage imaging with sub-cellular resolution using a laboratory-based phase-contrast x-ray microscope.

Feature Weighted Models (FWM) to address lineage dependency in drug-resistance prediction from Mycobacterium tuberculosis genome sequences (2023)
Journal Article
Chang, Y., Xia, D., & Billows, N. (2023). Feature Weighted Models (FWM) to address lineage dependency in drug-resistance prediction from Mycobacterium tuberculosis genome sequences. Bioinformatics, 39(7), https://doi.org/10.1093/bioinformatics/btad428

Background: Tuberculosis is caused by members of the Mycobacterium tuberculosis complex (MTBC) and is the second leading infectious killer after COVID-19. The evolution of drug-resistance poses a threat to successful treatment and disease eradication... Read More about Feature Weighted Models (FWM) to address lineage dependency in drug-resistance prediction from Mycobacterium tuberculosis genome sequences.

Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S., Belas, A., Marques, C., da Silva, J., Amaral, A., …Pomba, C. (2023). Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, https://doi.org/10.1007/s10096-023-04629-2

Extended-spectrum beta-lactamase (ESBL)- and plasmid-mediated cephalosporinase (AmpC)-producing Enterobacterales (ESBL/AmpC-E) are an increasing healthcare problem in both human and veterinary medicine. The aim of this study was to investigate the po... Read More about Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom.

Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S., Belas, A., Marques, C., da Silva, J. M., Amaral, A. J., …Pomba, C. (in press). Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, https://doi.org/10.1007/s10096-023-04629-2

Insufficient effect of sedation followed by difficulties inducing a colicking Shetland pony (2023)
Journal Article
Veen, I., & de Grauw, J. (2023). Insufficient effect of sedation followed by difficulties inducing a colicking Shetland pony. Vet Record Case Reports, https://doi.org/10.1002/vrc2.670

A Shetland pony suspected of large intestinal displacement was presented for exploratory laparotomy. The pony was extremely agitated with refractory pain despite repeated intravenous administration of detomidine and morphine. As the pony became unman... Read More about Insufficient effect of sedation followed by difficulties inducing a colicking Shetland pony.