Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner
(2017)
Journal Article
Schroeder, H., McCarthy, D., Szestak, T., Cook, D. A., Taylor, M., Craig, A. G., …Lawrence, R. A. (2017). Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner. PLoS Neglected Tropical Diseases, 11(5), e0005592. https://doi.org/10.1371/journal.pntd.0005592
Brugia malayi causes the human tropical disease, lymphatic filariasis. Microfilariae (Mf) of this nematode live in the bloodstream and are ingested by a feeding mosquito vector. Interestingly, in a remarkable co-evolutionary adaptation, Mf appearance... Read More about Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner.