Mutagenesis of Streptococcus equi and Streptococcus suis by transposon Tn917
Journal Article
Slater, J. D., Allen, A. G., May, J. P., Bolitho, S., Lindsay, H., & Maskell, D. J. Mutagenesis of Streptococcus equi and Streptococcus suis by transposon Tn917. Veterinary Microbiology, 93(3), 197-206. https://doi.org/10.1016/S0378-1135%2803%2900030-0
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Role of glycosylphosphatidylinositols in the activation of phospholipase A(2) and the neurotoxicity of prions
Journal Article
Bate, C., & Williams, A. Role of glycosylphosphatidylinositols in the activation of phospholipase A(2) and the neurotoxicity of prions. Journal of General Virology, 85(85), 3797-3804. https://doi.org/10.1099/vir.0.80366-0
Microglia kill amyloid-beta(1-42) damaged neurons by a CD14-dependent process
Journal Article
Bate, C., Veerhuis, R., Eikelenboom, P., & Williams, A. E. Microglia kill amyloid-beta(1-42) damaged neurons by a CD14-dependent process. NeuroReport, 15(9), 1427-1430. https://doi.org/10.1097/01.wnr.0000132203.76836.16
The role of platelet activating factor in prion and amyloid-beta neurotoxicity
Journal Article
Bate, C., Salmona, M., & Williams, A. The role of platelet activating factor in prion and amyloid-beta neurotoxicity. NeuroReport, 15(3), 509-513. https://doi.org/10.1097/01.wnr.0000113065.17279.7b
Squalestatin cures prion-infected neurons and protects against prion neurotoxicity
Journal Article
Bate, C., Salmona, M., Diomede, L., & Williams, A. Squalestatin cures prion-infected neurons and protects against prion neurotoxicity. Journal of Biological Chemistry, 279(15), 14983-14990. https://doi.org/10.1074/jbc.M313061200
Phospholipase A(2) inhibitors or platelet-activating factor antagonists prevent prion replication
Journal Article
Bate, C., Reid, S. W. J., & Williams, A. Phospholipase A(2) inhibitors or platelet-activating factor antagonists prevent prion replication. Journal of Biological Chemistry, 279(35), 36405-36411. https://doi.org/10.1074/jbc.M404086200
Manipulation of PrPres production in scrapie-infected neuroblastoma cells
Journal Article
Bate, C., Langeveld, J., & Williams, A. Manipulation of PrPres production in scrapie-infected neuroblastoma cells. Journal of Neuroscience Methods, 138(1-2), 217-223. https://doi.org/10.1016/j.jneumeth.2004.04.001
MRSA: an emerging equine problem?
Journal Article
Slater, J. D. MRSA: an emerging equine problem?. Equine Veterinary Journal, 37(6), 490-492
Eotaxin-1-regulated eosinophils have a critical role in innate immunity against experimental Brugia malayi infection
Journal Article
Simons, J. E., Rothenberg, M. E., & Lawrence, R. A. Eotaxin-1-regulated eosinophils have a critical role in innate immunity against experimental Brugia malayi infection. European Journal of Immunology, 35(1), 189-197. https://doi.org/10.1002/eji.200425541
Equine polysaccharide storage myopathy
Journal Article
Patterson-Kane, J. C., Slater, J. D., & McGowan, C. Equine polysaccharide storage myopathy. Veterinary Record, 156(14), 456-456
Canine diabetes mellitus: can old dogs teach us new tricks?
Journal Article
Catchpole, B., Ristic, J. M., Fleeman, L. M., & Davison, L. J. Canine diabetes mellitus: can old dogs teach us new tricks?. Diabetologia, 48(10), 1948-1956. https://doi.org/10.1007/s00125-005-1921-1
Microglial cells kill prion-damaged neurons in vitro by a CD14-dependent process
Journal Article
Bate, C., Boshuizen, R., & Williams, A. Microglial cells kill prion-damaged neurons in vitro by a CD14-dependent process. Journal of Neuroimmunology, 170(1-2), 62-70. https://doi.org/10.1016/j.jneuroim.2005.08.021
Cor pulmonale and respiratory disease: unique features of the equine cardiopulmonary system
Journal Article
Slater, J. D. Cor pulmonale and respiratory disease: unique features of the equine cardiopulmonary system. Equine Veterinary Education, 18(4), 188-190
Mutation of the maturase lipoprotein attenuates the virulence of Streptococcus equi to a greater extent than does loss of general lipoprotein lipidation
Journal Article
Hamilton, A., Robinson, C., Sutcliffe, I. C., Slater, J. D., Maskell, D. J., Davis-Poynter, N. J., …Harrington, D. J. Mutation of the maturase lipoprotein attenuates the virulence of Streptococcus equi to a greater extent than does loss of general lipoprotein lipidation. Infection and Immunity, 74(12), 6907-6919. https://doi.org/10.1128/IAI.01116-06
Prostaglandin D-2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells
Journal Article
Bate, C., Kempster, S., & Williams, A. Prostaglandin D-2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. Neuropharmacology, 50(2), 229-237. https://doi.org/10.1016/j.neuropharm.2005.09.008
Platelet-activating factor antagonists protect amyloid-beta damaged neurons from microglia-mediated death
Journal Article
Bate, C., Kempster, S., & Williams, A. Platelet-activating factor antagonists protect amyloid-beta damaged neurons from microglia-mediated death. Neuropharmacology, 51(2), 173-181. https://doi.org/10.1016/j.neuropharm.2006.02.015
Interferon-gamma increases neuronal death in response to amyloid-beta(1-42)
Journal Article
Bate, C., Kempster, S., Last, V., & Williams, A. Interferon-gamma increases neuronal death in response to amyloid-beta(1-42). https://doi.org/10.1186/1742-2094-3-7
Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide
Journal Article
Wilson, R., Bate, C., Boshuizen, R., Williams, A., & Brewer, J. Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide. BMC Neuroscience, 8,Background: Neurotoxic peptides derived from the protease-resistant core of the prion protein are used to model the pathogenesis of prion diseases. The current study characterised the ingestion, internalization and intracellular trafficking of a neur... Read More about Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide.
Canine DLA diversity: 3. Disease studies
Conference Proceeding
Kennedy, L. J., Barnes, A., Short, A., Brown, J. J., Seddon, J., Fleeman, L., …Ollier, W. E. R. Canine DLA diversity: 3. Disease studies. https://doi.org/10.1111/j.1399-0039.2006.00781.x
Simvastatin treatment prolongs the survival of scrapie-infected mice
Journal Article
Kempster, S., Bate, C., & Williams, A. Simvastatin treatment prolongs the survival of scrapie-infected mice. NeuroReport, 18(5), 479-482