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Piling behaviour in British layer flocks: Observations and farmers' èxperiences (2022)
Journal Article
Winter, J., Stratmann, A., Toscano, M. J., Cardwell, J. M., & Nicol, C. J. (2022). Piling behaviour in British layer flocks: Observations and farmers' èxperiences. Applied Animal Behaviour Science, 253, Article 105686. https://doi.org/10.1016/j.applanim.2022.105686

Smothering of laying hens, defined as death due to suffocation when hens tightly pile together in layer barns, is a well-known problem affecting the British loose-housed layer industry. However, knowledge about mechanisms contributing to piling in Br... Read More about Piling behaviour in British layer flocks: Observations and farmers' èxperiences.

Sentience in decapod crustaceans: A general framework and review of the evidence. Animal Sentience 32(1) (2022)
Journal Article
Crump, A., Browning, H., Schnell, A., Burn, C., & Birch, J. (2022). Sentience in decapod crustaceans: A general framework and review of the evidence. Animal Sentience 32(1). Animal Sentience, 32, Article 407. https://doi.org/10.51291/2377-7478.1691

We outline a framework for evaluating scientific evidence of sentience, focusing on pain experience. It includes eight neural and cognitive-behavioural criteria, with confidence levels for each criterion reflecting the reliability and quality of the... Read More about Sentience in decapod crustaceans: A general framework and review of the evidence. Animal Sentience 32(1).

Housing and Environmental Enrichment of the Domestic Ferret: A Multi-Sector Survey (2022)
Journal Article
Dancer, A. M., Díez-León, M., Bizley, J. K., & Burn, C. C. (2022). Housing and Environmental Enrichment of the Domestic Ferret: A Multi-Sector Survey. Animals, 12, Article 1065. https://doi.org/10.3390/ani12091065

Ferrets (Mustela putorius furo) are kept and used in multiple sectors of society, but little is known about how they are housed and what environmental enrichment (EE) they may benefit from. We aimed to help guide caretakers about what housing and EE... Read More about Housing and Environmental Enrichment of the Domestic Ferret: A Multi-Sector Survey.

Mitochondrial Dynamics in the Neonatal Brain -a potential target following injury? (2022)
Journal Article
Jones, A., & Thornton, C. (2022). Mitochondrial Dynamics in the Neonatal Brain -a potential target following injury?. Bioscience Reports, https://doi.org/10.1042/BSR20211696

The impact of birth asphyxia and its sequelae, hypoxic-ischaemic brain injury, is long lasting and significant, both for the infant and for their family. Treatment options are limited to therapeutic hypothermia, which is not universally successful an... Read More about Mitochondrial Dynamics in the Neonatal Brain -a potential target following injury?.

The effect of hard pecking enrichment during rear on feather cover, feather pecking behaviour and beak length in beak-trimmed and intact-beak laying hen pullets. (2022)
Journal Article
Baker, P. E., Nicol, C. J., & Weeks, C. A. (2022). The effect of hard pecking enrichment during rear on feather cover, feather pecking behaviour and beak length in beak-trimmed and intact-beak laying hen pullets. Animals,

Injurious Pecking, commonly controlled by beak trimming (BT) is a widespread issue in laying hens associated with thwarted foraging. This controlled study compared the effect in intact and beak-trimmed pullets of providing pecking pans to 8 treatment... Read More about The effect of hard pecking enrichment during rear on feather cover, feather pecking behaviour and beak length in beak-trimmed and intact-beak laying hen pullets..

A founder mutation in EHD1 presents with tubular proteinuria and deafness (2022)
Journal Article
Russell, C., Issler, N., Afonso, S., Ziegler, C., Weissman, . I., Dumitriu, S., …Schilling, A. (in press). A founder mutation in EHD1 presents with tubular proteinuria and deafness. Journal of the American Society of Nephrology,

Background: The endocytic reabsorption of proteins in the proximal tubule requires a complex machinery and defects can lead to tubular proteinuria. The precise mechanisms of endocytosis and processing of receptors and cargo are incompletely unders... Read More about A founder mutation in EHD1 presents with tubular proteinuria and deafness.

Assessing Animal Welfare: A triangulation of preference, judgement bias and other candidate welfare indicators (2021)
Journal Article
Paul, E., Browne, W., Mendl, M., Caplen, G., Trevarthen, A., Held, S., & Nicol, C. (in press). Assessing Animal Welfare: A triangulation of preference, judgement bias and other candidate welfare indicators. Animal Behaviour,

To assess the welfare of captive animals, validated measures – so called “welfare indicators” - are required. We used a triangulation approach to investigate the extent to which different measures converged to provide corroborating evidence of welfar... Read More about Assessing Animal Welfare: A triangulation of preference, judgement bias and other candidate welfare indicators.

Time to Loss of Behavioural and Brainstem Responses of Ducks Following Non-Stunned Slaughter (2021)
Journal Article
Gibson, T. (in press). Time to Loss of Behavioural and Brainstem Responses of Ducks Following Non-Stunned Slaughter. Animals, https://doi.org/10.3390/ani11123531

Non-stunned slaughter has been extensively described for other farmed species but there has been limited research on waterfowl. The study assessed 34 ducks in a non-stunned halal slaughter-house in Brazil for time to loss of consciousness using vario... Read More about Time to Loss of Behavioural and Brainstem Responses of Ducks Following Non-Stunned Slaughter.

Pandemic Puppies: Characterising motivations and behaviours of UK owners who purchased puppies during the 2020 COVID-19 Pandemic (2021)
Journal Article
Packer, R., Brand, C., Belshaw, Z., Pegram, C., Stevens, K., & O'Neill, D. (2021). Pandemic Puppies: Characterising motivations and behaviours of UK owners who purchased puppies during the 2020 COVID-19 Pandemic. Animals, 11(9), 2500. https://doi.org/10.3390/ani11092500

Attempts to control the spread of coronavirus during the COVID-19 Pandemic included periods of ‘lockdown’ in the UK, where many households spent several months at home with limited external social contact. Data from diverse sources suggest unusually... Read More about Pandemic Puppies: Characterising motivations and behaviours of UK owners who purchased puppies during the 2020 COVID-19 Pandemic.

The pen is milder than the blade: Identification marking mice using ink on the tail appears more humane than ear-punching even with local anaesthetic (2021)
Journal Article
Burn, C., Mazlan, N., Chancellor, N., & Wells, D. (2021). The pen is milder than the blade: Identification marking mice using ink on the tail appears more humane than ear-punching even with local anaesthetic. Animals, 11, https://doi.org/10.3390/ani11061664

Identification marking mice commonly involves ear-punching with or without anaesthetic, or tail-marking with ink. To identify which is most humane, we marked male BALB/c mice using ear-punching (EP), ear-punching with anaesthetic EMLATM cream (EP+A),... Read More about The pen is milder than the blade: Identification marking mice using ink on the tail appears more humane than ear-punching even with local anaesthetic.

Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists (2021)
Journal Article
Jones, G., Volk, H., & Packer, R. (in press). Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16144

Background: Epilepsy is the most common chronic neurological disease in dogs that impacts the quality of life (QoL) of affected dogs and their owners. Canine epilepsy research is expanding internationally, but where best to focus limited research tim... Read More about Future research priorities in canine epilepsy: viewpoints of owners, general practice veterinarians and neurology specialists.

Proportion and risk factors for death by euthanasia in dogs in the UK (2021)
Journal Article
O'Neill, D., Pegram, C., Gray, C., Packer, R. M., Richards, Y., Church, D. B., …O’Neill, D. G. (2021). Proportion and risk factors for death by euthanasia in dogs in the UK. International Journal of Advanced Scientific Engineering and Technological Research, https://doi.org/10.1038/s41598-021-88342-0

Objectives: To report proportional euthanasia or unassisted death, as well as the demographic and clinical factors associated with euthanasia, in dogs under primary veterinary care in the UK. Methods: A cohort study design to estimate proportional... Read More about Proportion and risk factors for death by euthanasia in dogs in the UK.

Handling mice using gloves sprayed with alcohol-based hand sanitiser: acute effects on mouse behaviour (2021)
Journal Article
Burn, C., Lopez Salesansky, N., Wells, D., Whitfield, L., & Chancellor, N. (2021). Handling mice using gloves sprayed with alcohol-based hand sanitiser: acute effects on mouse behaviour. Animal Technology and Welfare, 20, 11-20

Alcohols are commonly used in laboratory animal facilities to disinfect hands, equipment and laboratory environments. The effect on mice is unknown, so we observed male and female C57BL/6J and BALB/c mice during and after handling with nitrile gloves... Read More about Handling mice using gloves sprayed with alcohol-based hand sanitiser: acute effects on mouse behaviour.

Social buffering in horses is influenced by context but not by the familiarity and habituation of a companion (2021)
Journal Article
C, R., CJ, N., T, R., & DS, M. (in press). Social buffering in horses is influenced by context but not by the familiarity and habituation of a companion. Scientific Reports,

Social buffering applies when a companion can help to reduce the subject’s stress response during a stressful event and/or help to recover more quickly from a stressful event. The aim of this study was to determine if the social buffering function of... Read More about Social buffering in horses is influenced by context but not by the familiarity and habituation of a companion.

Global network analysis in Schizosaccharomyces pombe reveals three distinct consequences of the common 1-kb deletion causing juvenile CLN3 disease (2021)
Journal Article
Russell, C., Minnis, C. J., Townsend, S., Petschnigg, J., Tinelli, E., Bähler, J., …Mole, S. E. (2021). Global network analysis in Schizosaccharomyces pombe reveals three distinct consequences of the common 1-kb deletion causing juvenile CLN3 disease. Scientific Reports,

Juvenile CLN3 disease is a recessively inherited paediatric neurodegenerative disorder, with most patients homozygous for a 1-kb intragenic deletion in CLN3. The btn1 gene is the Schizosaccharomyces pombe orthologue of CLN3. Here, we have extended th... Read More about Global network analysis in Schizosaccharomyces pombe reveals three distinct consequences of the common 1-kb deletion causing juvenile CLN3 disease.

Early life exposure to air pollution impacts neuronal and glial cell function leading to impaired neurodevelopment (2021)
Journal Article
Morris, R. H., Counsell, S. J., McGonnell, I. M., & Thornton, C. (in press). Early life exposure to air pollution impacts neuronal and glial cell function leading to impaired neurodevelopment. BioEssays, 2000288. https://doi.org/10.1002/bies.202000288

The World Health Organisation recently listed air pollution as the most significant threat to human health. Air pollution comprises particulate matter (PM), metals, black carbon and gases such as ozone (O3), nitrogen dioxide (NO2) and carbon monoxide... Read More about Early life exposure to air pollution impacts neuronal and glial cell function leading to impaired neurodevelopment.