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The influence of risk factors associated with captive rearing on post-release survival in translocated cirl buntings Emberiza cirlus in the UK (2017)
Journal Article
Fountain, K. I., Jeffs, C., Croft, S., Gregson, J., Lister, J., Evans, A., Carter, I., Chang, Y. M., & Sainsbury, A. W. (2017). The influence of risk factors associated with captive rearing on post-release survival in translocated cirl buntings Emberiza cirlus in the UK. https://doi.org/10.1017/S0030605315001313

Population decline resulting from agricultural intensification led to contraction of the range of the cirl bunting Emberiza cirlus in the UK to a small area of south Devon. As part of the UK Biodiversity Action Plan for the species, a project to re-e... Read More about The influence of risk factors associated with captive rearing on post-release survival in translocated cirl buntings Emberiza cirlus in the UK.

Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes (2017)
Journal Article
Sanchis-Mora, S., Chang, Y. M., Abeyesinghe, S. M., Fisher, A., Volk, H. A., & Pelligand, L. (2017). Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes. Veterinary Anaesthesia and Analgesia, 44(3), 600-614. https://doi.org/10.1016/j.vaa.2016.09.004

Objective

To study feasibility and test-retest repeatability of a sensory threshold examination protocol (STEP) and report quantitative sensory threshold distributions in healthy dogs.

Study design

Prospective, observational, cohort study.... Read More about Development and initial validation of a sensory threshold examination protocol (STEP) for phenotyping canine pain syndromes.

Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers (2017)
Journal Article
Mahendran, S. A., Huxley, J. N., Chang, Y. M., Burnell, M., Barrett, D. C., Whay, H. R., Blackmore, T. L., Mason, C. S., & Bell, N. J. (2017). Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers. https://doi.org/10.1016/j.tvjl.2017.01.011

The objective of this study was to assess both independent and combined effects of routine foot trimming of heifers at 3 weeks pre-calving and 100 days post calving on the first lactation lameness and lactation productivity. A total of 419 pre-calvin... Read More about Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers.

Interaction of chlorhexidine with trisEDTA or miconazole in vitro against canine meticillin-resistant and susceptible Staphylococcus pseudintermedius isolates from two UK regions (2016)
Journal Article
Clark, S. M., Schmidt, V. M., Chang, Y. M., Wilson, A., Timofte, D., Bond, R., & Loeffler, A. (2016). Interaction of chlorhexidine with trisEDTA or miconazole in vitro against canine meticillin-resistant and susceptible Staphylococcus pseudintermedius isolates from two UK regions. Veterinary Dermatology, 27(5), 340+. https://doi.org/10.1111/vde.12357

Serum Biochemical Phenotypes in the Domestic Dog (2016)
Journal Article
Chang, Y. M., Hadox, E., Szladovits, B., & Garden, O. A. (2016). Serum Biochemical Phenotypes in the Domestic Dog. PLoS ONE, 11(2), e0149650. https://doi.org/10.1371/journal.pone.0149650

The serum or plasma biochemical profile is essential in the diagnosis and monitoring of systemic disease in veterinary medicine, but current reference intervals typically take no account of breed-specific differences. Breed-specific hematological phe... Read More about Serum Biochemical Phenotypes in the Domestic Dog.

Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing (2015)
Journal Article
Javaheri, B., Carriero, A., Staines, K. A., Chang, Y. M., Houston, D. A., Oldknow, K. J., Millan, J. L., Kazeruni, B. N., Salmon, P., Shefelbine, S., Farquharson, C., & Pitsillides, A. A. (2015). Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing. BONE, 81, 277-291. https://doi.org/10.1016/j.bone.2015.07.035

PHOSPHO1 is one of principal proteins involved in initiating bone matrix mineralisation. Recent studies have found that Phospho1 KO mice (Phospho1-R74X) display multiple skeletal abnormalities with spontaneous fractures, bowed long bones, osteomalaci... Read More about Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing.

Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure (2015)
Journal Article
Baker, L. A., Lee, K. C. L., Jimenez, C. P., Alibhai, H. I. K., Chang, Y. M., Leckie, P. J., Mookerjee, R. P., Davies, N. A., Andreola, F., & Jalan, R. (2015). Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure. PLoS ONE, 10(5), https://doi.org/10.1371/journal.pone.0128076

Acute liver failure is a rare but catastrophic condition which can progress rapidly to multi-organ failure. Studies investigating the onset of individual organ injury such as the liver, kidneys and brain during the evolution of acute liver failure, a... Read More about Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure.