Ontogenetic changes in the body plan of the sauropodomorph dinosaur Mussaurus patagonicus reveal shifts of locomotor stance during growth (2019)
Journal Article
Otero, A., Cuff, A. R., Allen, V., Sumner-Rooney, L., Pol, D., & Hutchinson, J. R. (2019). Ontogenetic changes in the body plan of the sauropodomorph dinosaur Mussaurus patagonicus reveal shifts of locomotor stance during growth. https://doi.org/10.1038/s41598-019-44037-1

Ontogenetic information is crucial to understand life histories and represents a true challenge in dinosaurs due to the scarcity of growth series available. Mussaurus patagonicus was a sauropodomorph dinosaur close to the origin of Sauropoda known fr... Read More about Ontogenetic changes in the body plan of the sauropodomorph dinosaur Mussaurus patagonicus reveal shifts of locomotor stance during growth.

What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol (2019)
Journal Article
Packer, R. M. A., Davies, A. M., Volk, H. A., Puckett, H. L., Hobbs, S. L., & Fowkes, R. C. (2019). What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol. PLoS ONE, 14(5), e0216000. https://doi.org/10.1371/journal.pone.0216000

Hair is an emerging biological matrix in which to measure chronic HPA axis activity, offering a longer term view into an animal’s life. We explored effects of exogenous (e.g. lifestyle, medications, social environment) and endogenous (e.g. disease, b... Read More about What can we learn from the hair of the dog? Complex effects of endogenous and exogenous stressors on canine hair cortisol.

Foot pressure distribution in White Rhinoceroses (Ceratotherium simum) during walking (2019)
Journal Article
Panagiotopoulou, O., Pataky, T. C., & Hutchinson, J. R. (2019). Foot pressure distribution in White Rhinoceroses (Ceratotherium simum) during walking. PeerJ, 7, e6881. https://doi.org/10.7717/peerj.6881

White rhinoceroses (Ceratotherium simum) are odd-toed ungulates that belong to the group Perissodactyla. Being second only to elephants in terms of large body mass amongst extant tetrapods, rhinoceroses make fascinating subjects for the study of how... Read More about Foot pressure distribution in White Rhinoceroses (Ceratotherium simum) during walking.

Exploring mitochondrial cholesterol (mChol) signalling for therapeutic intervention in neurological conditions (2019)
Journal Article
Desai, R., & Campanella, M. (2019). Exploring mitochondrial cholesterol (mChol) signalling for therapeutic intervention in neurological conditions. British Journal of Pharmacology, https://doi.org/10.1111/bph.14697

The pharmacological targeting of cholesterol levels continues to draw interest due to the vast success of therapeutics such as statins in extending life expectancy by modifying the prognosis of diseases associated with the impairment of the lipid met... Read More about Exploring mitochondrial cholesterol (mChol) signalling for therapeutic intervention in neurological conditions.

The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata (2019)
Journal Article
Collings, A. J., Porro, L. B., Hill, C., & Richards, C. T. (2019). The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata. Royal Society Open Science, 6, 190060. https://doi.org/10.1098/rsos.190060

Some frog species, such as Kassina maculata (red-legged running frog), use an asynchronous walking/running gait as their primary locomotor mode. Prior comparative anatomy work has suggested that lateral rotation of the pelvis improves walking perform... Read More about The impact of pelvic lateral rotation on hindlimb kinematics and stride length in the red-legged running frog, Kassina maculata.

Evolutionary parallelisms of pectoral and pelvic network-anatomy from fins to limbs (2019)
Journal Article
Esteve-Altava, B., Pierce, S. E., Molnar, J. L., Johnston, P., Diogo, R., & Hutchinson, J. R. (2019). Evolutionary parallelisms of pectoral and pelvic network-anatomy from fins to limbs. Science Advances, 5(5), https://doi.org/10.1126/sciadv.aau7459

Lobe-fins transformed into limbs during the Devonian period, facilitating the water-to-land transition in tetrapods. We traced the evolution of well-articulated skeletons across the fins-to-limbs transition, using a network-based approach to quantify... Read More about Evolutionary parallelisms of pectoral and pelvic network-anatomy from fins to limbs.

High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia (2019)
Journal Article
Yurchenko, A. A., Deniskova, T. E., Yudin, N. S., Dotsev, A. V., Khamiruev, T. N., Selionova, M. I., Egorov, S. V., Reyer, H., Wimmers, K., Brem, G., Zinovieva, N. A., & Larkin, D. M. (2019). High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia. BMC Genomics, 20(Suppl 3), https://doi.org/10.1186/s12864-019-5537-0

Domestication and centuries of selective breeding have changed genomes of sheep breeds to respond to environmental challenges and human needs. The genomes of local breeds, therefore, are valuable sources of genomic variants to be used to understand m... Read More about High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia.

The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait (2019)
Journal Article
Bishop, P. J., Scofield, R. P., & Hocknull, S. A. (2019). The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait. https://doi.org/10.1080/03115518.2019.1594380

The extinct, flightless moa of New Zealand included some of the largest birds to have existed and possessed many distinguishing pelvic and hindlimb osteological features. These features may have influenced stance and gait in moa compared with extant... Read More about The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait.

FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy (2019)
Journal Article
Soutar, M. P. M., Kempthorne, L., Annuario, E., Luft, C., Wray, S., Ketteler, R., Ludtmann, M. H. R., & Plun-Favreau, H. (2019). FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy. Autophagy, https://doi.org/10.1080/15548627.2019.1603549

Mitochondrial quality control is essential for maintaining a healthy population of mitochondria. Two proteins associated with Parkinson disease, the kinase PINK1 and the E3 ubiquitin ligase PRKN, play a central role in the selective degradation of he... Read More about FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy.

Polyunsaturated fatty acids influence offspring sex ratio in cows (2019)
Journal Article
Marei, W. F. A., Khalil, W. A., Pushpakumara, P. G. A., El-Harairy, M. A., Abo El-Atta, A. M. A., Wathes, D. C., & Fouladi-Nashta, A. A. (2019). Polyunsaturated fatty acids influence offspring sex ratio in cows. https://doi.org/10.1016/j.ijvsm.2018.01.006

Dietary polyunsaturated fatty acids (PUFAs) can influence fertility in farm animals. Some evidence in mice and sheep have suggested that PUFAs may influence offspring sex ratio, which may have significant value for cattle production. To test this hyp... Read More about Polyunsaturated fatty acids influence offspring sex ratio in cows.

Zebrafish as a model for kidney function and disease (2019)
Journal Article
Outtandy, P., Russell, C., Kleta, R., & Brockenhauer, D. (2019). Zebrafish as a model for kidney function and disease. Pediatric Nephrology, 34(5), 751-762. https://doi.org/10.1007/s00467-018-3921-7

Kidney disease is a global problem with around three million people diagnosed in the UK alone and the incidence is rising. Research is critical to develop better treatments. Animal models can help to better understand the pathophysiology behind the v... Read More about Zebrafish as a model for kidney function and disease.

The Role Of Fstl3 In Spermatogenesis: A Transcriptome Analysis (2019)
Presentation / Conference Contribution
Ballesteros, R., Xia, D., O'Shaughnessy, P., & Mukherjee, A. The Role Of Fstl3 In Spermatogenesis: A Transcriptome Analysis

Spermatogenesis in mammals depends on the function of Sertoli cells (SC). The total number of SC present in the testes is determined in the pre-pubertal stages of development. Activin, a TGFβ family ligand, regulates SC proliferation in the early pos... Read More about The Role Of Fstl3 In Spermatogenesis: A Transcriptome Analysis.

Germline-restricted chromosome (GRC) is widespread among songbirds (2019)
Journal Article
Torgasheva, A. A., Malinovskaya, L. P., Zadesenets, K. S., Karamysheva, T. V., Kizilova, E. A., Akberdina, E. A., Pristyazhnyuk, I. E., Shnaider, E. P., Volodkina, V. A., Saifitdinova, A. F., Galkina, S. A., Larkin, D. M., Rubtsov, N. B., & Borodin, P. M. (2019). Germline-restricted chromosome (GRC) is widespread among songbirds. https://doi.org/10.1073/pnas.1817373116

An unusual supernumerary chromosome has been reported for two related avian species, the zebra and Bengalese finches. This large, germline-restricted chromosome (GRC) is eliminated from somatic cells and spermatids and transmitted via oocytes only. I... Read More about Germline-restricted chromosome (GRC) is widespread among songbirds.

Faculty Perception of an Embedded Research Project in the Undergraduate Veterinary Curriculum (2019)
Journal Article
Cehrs, E., Pelligand, L., & Weller, R. (2019). Faculty Perception of an Embedded Research Project in the Undergraduate Veterinary Curriculum. Journal of Veterinary Medical Education,

In this article, we describe faculty’s perception of a research project embedded in the final year of the undergraduate veterinary curriculum and look at factors associated with overall perceptions of the project. We hypothesized that faculty would h... Read More about Faculty Perception of an Embedded Research Project in the Undergraduate Veterinary Curriculum.

Understanding mechanobiology in cultured endothelium: A review of the orbital shaker method (2019)
Journal Article
Warboys, C. M., Ghim, M., & Weinberg, P. D. (2019). Understanding mechanobiology in cultured endothelium: A review of the orbital shaker method. Atherosclerosis, 285, 170-177. https://doi.org/10.1016/j.atherosclerosis.2019.04.210

A striking feature of atherosclerosis is its highly non-uniform distribution within the arterial tree. This has been attributed to variation in the haemodynamic wall shear stress (WSS) experienced by endothelial cells, but the WSS characteristics tha... Read More about Understanding mechanobiology in cultured endothelium: A review of the orbital shaker method.

Genome-wide association study for body weight in cattle populations from Siberia (2019)
Journal Article
Igoshin, A. V., Yudin, N. S., Belonogova, N. M., & Larkin, D. M. (2019). Genome-wide association study for body weight in cattle populations from Siberia. Animal Genetics, 50(3), 250-253. https://doi.org/10.1111/age.12786

Body weight is a complex trait in cattle associated with commonly used commercial breeding measurements related to growth. Although many quantitative trait loci (QTL) for body weight have been identified in cattle so far, searching for genetic determ... Read More about Genome-wide association study for body weight in cattle populations from Siberia.

Pretectal projections to the oculomotor cerebellum in hummingbirds ( Calypte anna ), zebra finches ( Taeniopygia guttata ), and pigeons ( Columba livia ) (2019)
Journal Article
Gaede, A. H., Gutierrez‐Ibanez, C., Armstrong, M. S., Altshuler, D. L., & Wylie, D. R. (2019). Pretectal projections to the oculomotor cerebellum in hummingbirds ( Calypte anna ), zebra finches ( Taeniopygia guttata ), and pigeons ( Columba livia ). Journal of Comparative Neurology, 527(16), 2644-2658. https://doi.org/10.1002/cne.24697

In birds, optic flow is processed by a retinal‐recipient nucleus in the pretectum, the nucleus lentiformis mesencephali (LM), which then projects to the cerebellum, a key site for sensorimotor integration. Previous studies have shown that the LM is h... Read More about Pretectal projections to the oculomotor cerebellum in hummingbirds ( Calypte anna ), zebra finches ( Taeniopygia guttata ), and pigeons ( Columba livia ).

Levothyrox® new and old formulations: are they switchable for millions of patients? (2019)
Journal Article
Concordet, D., Gandia, P., Montastruc, J. L., Bousquet-Mélou, A., Lees, P., Ferran, A., & Toutain, P. L. (2019). Levothyrox® new and old formulations: are they switchable for millions of patients?. Clinical Pharmacokinetics, https://doi.org/10.1007/s40262-019-00747-3

Effect of oral administration of pioglitazone on follicular dynamics in Holstein dairy cows (2019)
Journal Article
Yousefi, A. R., Kohram, H., Zare Shahneh, A., Zamiri, M. J., Dirandeh, E., Kazemi Khoozani, M., Dadashpour Davachi, N., Zhandi, M., & Fouladi-Nashta, A. A. (2019). Effect of oral administration of pioglitazone on follicular dynamics in Holstein dairy cows. Livestock Science, 224, 50-56. https://doi.org/10.1016/j.livsci.2019.04.001

This study investigated the effects of oral administration of pioglitazone (PGT), a specific and synthetic ligand of peroxisome proliferator-activated receptors gamma (PPARγ), on follicular dynamics and corpus luteum (CL) functionality in dairy cows.... Read More about Effect of oral administration of pioglitazone on follicular dynamics in Holstein dairy cows.

Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling (2019)
Journal Article
Alyodawi, K., Vermeij, W. P., Omairi, S., Kretz, O., Hopkinson, M., Solagna, F., Joch, B., Brandt, R. M. C., Barnhoorn, S., Van Vliet, N., Ridwan, Y., Essers, J., Mitchell, R., Morash, T., Pasternack, A., Ritvos, O., Matsakas, A., Collins-Hooper, H., Huber, T. B., Hoeijmakers, J. H. J., & Patel, K. (2019). Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling. Journal of Cachexia, Sarcopenia and Muscle, https://doi.org/10.1002/jcsm.12404