Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins (2017)
Journal Article
Wiens, O., Xia, D., Von Schubert, C., Wastling, J. M., Dobbelaere, D. A., Heussler, V. T., & Woods, K. L. (2017). Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins. PLoS ONE, 9(7), e103821. https://doi.org/10.1371/journal.pone.0103821

The invasion of Theileria sporozoites into bovine leukocytes is rapidly followed by the destruction of the surrounding host cell membrane, allowing the parasite to establish its niche within the host cell cytoplasm. Theileria infection induces host c... Read More about Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins.

Does the computed tomographic appearance of the lung differ between young and old dogs? (2017)
Journal Article
Hornby, N. L., & Lamb, C. R. (2017). Does the computed tomographic appearance of the lung differ between young and old dogs?. https://doi.org/10.1111/vru.12532

Demography and disorders of German Shepherd Dogs under primary veterinarycare in the UK (2017)
Journal Article
O'Neill, D. G., Coulson, N. R., Church, D. B., & Brodbelt, D. C. (2017). Demography and disorders of German Shepherd Dogs under primary veterinarycare in the UK. Canine Genetics and Epidemiology, 4(7), https://doi.org/10.1186/s40575-017-0046-4

The German Shepherd Dog (GSD) has been widely used for a variety of working roles. However, concerns for the health and welfare of the GSD have been widely aired and there is evidence that breed numbers are now in decline in the UK. Accurate demograp... Read More about Demography and disorders of German Shepherd Dogs under primary veterinarycare in the UK.

Tempo and mode of performance evolution across multiple independent origins of adhesive toe pads in lizards (2017)
Journal Article
Hagey, T. J., Uyeda, J. C., Crandell, K. E., Cheney, J. A., Autumn, K., & Harmon, L. J. (2017). Tempo and mode of performance evolution across multiple independent origins of adhesive toe pads in lizards. Evolution, 71(10), 2344-2358. https://doi.org/10.1111/evo.13318

Understanding macroevolutionary dynamics of trait evolution is an important endeavor in evolutionary biology. Ecological opportunity can liberate a trait as it diversifies through trait space, while genetic and selective constraints can limit diversi... Read More about Tempo and mode of performance evolution across multiple independent origins of adhesive toe pads in lizards.

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity (2017)
Journal Article
Doyle, S. R., Bourguinat, C., Nana-Djeunga, H. C., Kengne-Ouafo, J. A., Pion, S. D. S., Bopda, J., Kamgno, J., Wanji, S., Che, H., Kuesel, A., Walker, M., Basáñez, M.-G., Boakye, D. A., Osei-Atweneboana, M. Y., Boussinesq, M., Prichard, R. K., & Grant, W. N. (2017). Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity. PLoS Neglected Tropical Diseases, 11, e0005816. https://doi.org/10.1371/journal.pntd.0005816

Investigation of the association between serum protein concentrations and concurrent chronic kidney disease in hyperthyroid cats (2017)
Journal Article
Williams, T. L., Elliott, J., Syme, H. M., & Archer, J. (2017). Investigation of the association between serum protein concentrations and concurrent chronic kidney disease in hyperthyroid cats. Research in Veterinary Science, 115, 412-417. https://doi.org/10.1016/j.rvsc.2017.07.023

Our objective was to identify if changes in serum protein concentrations occur in hyperthyroidism and to assess their association with the development of azotaemia following treatment.

Initially non-azotaemic hyperthyroid cats and healthy older ca... Read More about Investigation of the association between serum protein concentrations and concurrent chronic kidney disease in hyperthyroid cats.

Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta) (2017)
Journal Article
Suárez-Bonnet, A., Grau-Bassas, E. R., Herráez, P., Quesada-Canales, O., Priestnall, S. L., & De Los Monteros, A. E. (2017). Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta). Journal of Comparative Pathology, 157(2-3), 85-89. https://doi.org/10.1016/j.jcpa.2017.06.009

Naturally occurring mammary tumours are uncommon in prosimians. A 20-year-old female ring-tailed lemur (Lemur catta) developed bilateral enlargement of the mammary glands. Surgical removal revealed that both masses were comprised of multiple nodules... Read More about Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta).

Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella (2017)
Journal Article
Kundu, K., Garg, R., Kumar, S., Mandal, M., Tomley, F. M., Blake, D. P., & Banerjee, P. S. (2017). Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella. Veterinary Parasitology, 244, 44-53. https://doi.org/10.1016/j.vetpar.2017.07.025

Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens. Immune mapped protein-1 (IMP-1) has been identified as an anticoccidial vaccine cand... Read More about Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella.

A distinctive patchy osteomalacia characterises Phospho1-deficient mice (2017)
Journal Article
Boyde, A., Staines, K. A., Javaheri, B., Millan, J. L., Pitsillides, A. A., & Farquharson, C. (2017). A distinctive patchy osteomalacia characterises Phospho1-deficient mice. Journal of Anatomy, 231(2), 293-308. https://doi.org/10.1111/joa.12628

The phosphatase PHOSPHO1 is involved in the initiation of biomineralisation. Bones in Phospho1 knockout (KO) mice show histological osteomalacia with frequent bowing of long bones and spontaneous fractures: they contain less mineral, with smaller min... Read More about A distinctive patchy osteomalacia characterises Phospho1-deficient mice.

Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach (2017)
Journal Article
Métras, R., Fournié, G., Dommergues, L., Camacho, A., Cavalerie, L., Mérot, P., Keeling, M. J., Cêtre-Sossah, C., Cardinale, E., & Edmunds, W. J. (2017). Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach. PLoS Neglected Tropical Diseases, 11(7), e0005767. https://doi.org/10.1371/journal.pntd.0005767

Rift Valley fever (RVF) is a major zoonotic and arboviral hemorrhagic fever. The conditions leading to RVF epidemics are still unclear, and the relative role of climatic and anthropogenic factors may vary between ecosystems. Here, we estimate the mos... Read More about Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach.

Computed tomographic morphometry of tympanic bulla shape and position in brachycephalic and mesaticephalic dog breeds (2017)
Journal Article
Mielke, B., Lam, R. W., & Ter Haar, G. (2017). Computed tomographic morphometry of tympanic bulla shape and position in brachycephalic and mesaticephalic dog breeds. https://doi.org/10.1111/vru.12529

Anatomic variations in skull morphology have been previously described for brachycephalic dogs; however there is little published information on interbreed variations in tympanic bulla morphology. This retrospective observational study aimed to (1) p... Read More about Computed tomographic morphometry of tympanic bulla shape and position in brachycephalic and mesaticephalic dog breeds.

Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration (2017)
Journal Article
Burkitt, M. D., Williams, J. M., Townsend, T., Hough, R., & Pritchard, D. M. (2017). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration. https://doi.org/10.1038/cddis.2017.332

Tamoxifen (TAM) has recently been shown to cause acute gastric atrophy and metaplasia in mice. We have previously demonstrated that the outcome of Helicobacter felis infection, which induces similar gastric lesions in mice, is altered by deletion of... Read More about Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration.

The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness (2017)
Journal Article
Walker, M., Pion, S. D. S., Fang, H., Gardon, J., Kamgno, J., Basáñez, M.-G., & Boussinesq, M. (2017). The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness. Clinical Infectious Diseases, 65(12), 2026-2034. https://doi.org/10.1093/cid/cix616

Background: Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca vol... Read More about The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness.

Treatment of dogs with compensated myxomatous mitral valve disease with spironolactone-a pilot study (2017)
Journal Article
Hezzell, M. J., Boswood, A., Lopez-Alvarez, J., Lotter, N. S., & Elliott, J. (2017). Treatment of dogs with compensated myxomatous mitral valve disease with spironolactone-a pilot study. Journal of Veterinary Cardiology, 19(4), 325-328. https://doi.org/10.1016/j.jvc.2017.06.001

Spironolactone improves outcome in dogs with advanced myxomatous mitral valve disease (MMVD). Its efficacy in preclinical MMVD is unknown. The hypothesis was the administration of spironolactone to dogs with compensated MMVD demonstrating risk factor... Read More about Treatment of dogs with compensated myxomatous mitral valve disease with spironolactone-a pilot study.

Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam (2017)
Journal Article
Delabouglise, A., Choisy, M., Phan, T. D., Antoine-Moussiaux, N., Peyre, M., Vu, T. D., Pfeiffer, D. U., & Fournié, G. (2017). Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam. Scientific Reports, 7, 5905. https://doi.org/10.1038/s41598-017-06244-6

While climate is often presented as a key factor influencing the seasonality of diseases, the importance of anthropogenic factors is less commonly evaluated. Using a combination of methods-wavelet analysis, economic analysis, statistical and disease... Read More about Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam.

Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds (2017)
Journal Article
Bishop, P. J., Clemente, C. J., Weems, R. E., Graham, D. F., Lamas, L. P., Hutchinson, J. R., Rubenson, J., Wilson, R. S., Hocknull, S. A., Barrett, R. S., & Lloyd, D. G. (2017). Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds. https://doi.org/10.1098/rsif.2017.0276

How extinct, non-avian theropod dinosaurs locomoted is a subject of considerable interest, as is the manner in which it evolved on the line leading to birds. Fossil footprints provide the most direct evidence for answering these questions. In this st... Read More about Using step width to compare locomotor biomechanics between extinct, non-avian theropod dinosaurs and modern obligate bipeds.

Gearing effects of the patella (knee extensor muscle sesamoid) of the helmeted guineafowl during terrestrial locomotion (2017)
Journal Article
Allen, V. R., Kambic, R. E., Gatesy, S. M., & Hutchinson, J. R. (2017). Gearing effects of the patella (knee extensor muscle sesamoid) of the helmeted guineafowl during terrestrial locomotion. Journal of Zoology, 303(3), 178-187. https://doi.org/10.1111/jzo.12485

Human patellae (kneecaps) are thought to act as gears, altering the mechanical advantage of knee extensor muscles during running. Similar sesamoids have evolved in the knee extensor tendon independently in birds, but it is unknown if these also affec... Read More about Gearing effects of the patella (knee extensor muscle sesamoid) of the helmeted guineafowl during terrestrial locomotion.

Molecular characterisation of protist parasites in human-habituated mountain gorillas (Gorilla beringei beringei), humans and livestock, from Bwindi impenetrable National Park, Uganda (2017)
Journal Article
Nolan, M. J., Unger, M., Yeap, Y. T., Rogers, E., Millet, I., Harman, K., Fox, M. T., Kalema-Zikusoka, G., & Blake, D. P. (2017). Molecular characterisation of protist parasites in human-habituated mountain gorillas (Gorilla beringei beringei), humans and livestock, from Bwindi impenetrable National Park, Uganda. https://doi.org/10.1186/s13071-017-2283-5

Over 60 % of human emerging infectious diseases are zoonotic, and there is growing evidence of the zooanthroponotic transmission of diseases from humans to livestock and wildlife species, with major implications for public health, economics, and cons... Read More about Molecular characterisation of protist parasites in human-habituated mountain gorillas (Gorilla beringei beringei), humans and livestock, from Bwindi impenetrable National Park, Uganda.

Can malignant and inflammatory pleural effusions in dogs be distinguished using computed tomography (2017)
Journal Article
Watton, T. C., Lara-Garcia, A., & Lamb, C. R. (2017). Can malignant and inflammatory pleural effusions in dogs be distinguished using computed tomography. Epidemiology and Infection, 58(5), 535-541. https://doi.org/10.1111/vru.12534

Computed tomography (CT) is the primary imaging modality used to investigate human patients with suspected malignant or inflammatory pleural effusion, but there is a lack of information about the clinical use of this test in dogs. To identify CT sign... Read More about Can malignant and inflammatory pleural effusions in dogs be distinguished using computed tomography.

Bestial boredom: a biological perspective on animal boredom and suggestions for its scientific investigation (2017)
Journal Article
Burn, C. C. (2017). Bestial boredom: a biological perspective on animal boredom and suggestions for its scientific investigation. Animal Behaviour, 130, 141-151. https://doi.org/10.1016/j.anbehav.2017.06.006

Boredom is likely to have adaptive value in motivating exploration and learning, and many animals may possess the basic neurological mechanisms to support it. Chronic inescapable boredom can be extremely aversive, and understimulation can harm neural... Read More about Bestial boredom: a biological perspective on animal boredom and suggestions for its scientific investigation.