Skip to main content

Research Repository

Advanced Search

All Outputs (54)

Dietary magnesium supplementation in cats with chronic kidney disease: A prospective double-blind randomized controlled trial (2024)
Journal Article
Tang, P., van den Broek, D., Jepson, R., Geddes, R., Chang, Y., Loetter, N., Moniot, D., Biourge, V., & Elliott, J. (2024). Dietary magnesium supplementation in cats with chronic kidney disease: A prospective double-blind randomized controlled trial. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.17134

Background: Plasma total magnesium concentration (tMg) is a prognostic indicator in cats with chronic kidney disease (CKD), shorter survival time being associated with hypomagnesemia. Whether this risk factor is modifiable with dietary magnesium supp... Read More about Dietary magnesium supplementation in cats with chronic kidney disease: A prospective double-blind randomized controlled trial.

Risk factors and implications associated with ultrasound-diagnosed nephrocalcinosis in cats with chronic kidney disease (2024)
Journal Article
Tang, P.-K., Geddes, R. F., Chang, Y.-M., Jepson, R. E., Van Den Broek, D. H. N., Lötter, N., & Elliott, J. (in press). Risk factors and implications associated with ultrasound-diagnosed nephrocalcinosis in cats with chronic kidney disease. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.17034

Background: Microscopic nephrocalcinosis is a common pathological feature of

Detection of nephrocalcinosis using ultrasonography, micro-computed tomography, and histopathology in cats (2024)
Journal Article
Tang, P., Geddes, R., Chang, Y., Jepson, R., van den Broek, D., Lötter, N., & Elliott, J. (2024). Detection of nephrocalcinosis using ultrasonography, micro-computed tomography, and histopathology in cats. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.17011

BackgroundIdentification of nephrocalcinosis in cats with chronic kidney disease (CKD) is of clinical interest but the ability of ultrasonography to detect nephrocalcinosis is uncertain.ObjectivesTo compare ultrasonography, micro-computed tomography... Read More about Detection of nephrocalcinosis using ultrasonography, micro-computed tomography, and histopathology in cats.

International Renal Interest Society best practice consensus guidelines for the diagnosis and management of acute kidney injury in cats and dogs (2024)
Journal Article
Segev, G., Cortellini, S., Foster, J. D., Francey, T., Langston, C., Londoño, L., Schweighauser, A., & Jepson, R. E. (2024). International Renal Interest Society best practice consensus guidelines for the diagnosis and management of acute kidney injury in cats and dogs. The Veterinary Journal, https://doi.org/10.1016/j.tvjl.2024.106068

Rapid typing of Klebsiella pneumoniae and Pseudomonas aeruginosa by Fourier-transform Infrared spectroscopy informs infection control in veterinary settings (2024)
Journal Article
Zendri, F., Schmidt, V., Mauder, N., Loeffler, A., Jepson, R. E., Isgren, C., Pinchbeck, G., Haldenby, S., Timofte, D., Leclercq, S. O., Ambretti, S., Polyclinic, O., Achour, W., Bisognin, F., & Timofte, D. (2024). Rapid typing of Klebsiella pneumoniae and Pseudomonas aeruginosa by Fourier-transform Infrared spectroscopy informs infection control in veterinary settings. Frontiers in Microbiology, https://doi.org/10.3389/fmicb.2024.1334268

Introduction: The emergence of multi-drug resistant (MDR) pathogens linked to healthcare-associated infections (HCAIs) is an increasing concern in modern veterinary practice. Thus, rapid bacterial typing for real-time tracking of MDR hospital dissemi... Read More about Rapid typing of Klebsiella pneumoniae and Pseudomonas aeruginosa by Fourier-transform Infrared spectroscopy informs infection control in veterinary settings.

Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019) (2022)
Journal Article
Beeston, D., Jepson, R., & Cortellini, S. (2022). Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019). Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13530

Title: Evaluation of presentation, treatment and outcome in hypertensive emergency in dogs and cats: 15 cases (2003-2019).
Introduction: Hypertensive emergency (HE) is well-recognised in human medicine, yet there is limited veterinary evidence. This... Read More about Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019).

Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass (2022)
Journal Article
Starybrat, D., Jepson, R., Bristow, P., Peterson, S., Yerramilli, M., Yerramilli, M., Chang, Y.-M., & Cortellini, S. (online). Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass. Journal of Veterinary Emergency and Critical Care,

Objective - Assess the occurrence of acute kidney injury (AKI) in dogs undergoing cardiac surgery under cardiopulmonary bypass (CPB) and explore associations between traditional and novel serum and urinary biomarkers.
Design – Prospective cohort st... Read More about Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass.

First Genome-Wide Association Study Investigating Blood Pressure and Renal Traits in Domestic Cats (2022)
Journal Article
Jepson, R. E., Warren, H., Syme, H. M., Elliott, J., & Munroe, P. B. (2022). First Genome-Wide Association Study Investigating Blood Pressure and Renal Traits in Domestic Cats. Scientific Reports, https://doi.org/10.1038/s41598-022-05494-3

Hypertension (HTN) and chronic kidney disease (CKD) are common in ageing cats. In humans, blood pressure (BP) and renal function are complex heritable traits. We performed the first feline Genome-Wide Association Study (GWAS) of quantitative traits s... Read More about First Genome-Wide Association Study Investigating Blood Pressure and Renal Traits in Domestic Cats.

Risk factors associated with disturbances of calcium homeostasis after initiation of a phosphate-restricted diet in cats with chronic kidney disease (2020)
Journal Article
Jepson, R., Elliott, J., Geddes, R., Chang, Y.-M., & Tang, P. (2020). Risk factors associated with disturbances of calcium homeostasis after initiation of a phosphate-restricted diet in cats with chronic kidney disease. Journal of Veterinary Internal Medicine, 1-12. https://doi.org/10.1111/jvim.15996

Background

Dietary phosphate restriction improves survival in cats with chronic kidney disease (CKD). However, feeding a phosphate‐restricted diet may disrupt calcium homeostasis leading to hypercalcemia in some cats.

Objectives

To identify... Read More about Risk factors associated with disturbances of calcium homeostasis after initiation of a phosphate-restricted diet in cats with chronic kidney disease.

Dysautonomia in 53 cats and dogs: retrospective review of clinical data and outcome (2020)
Journal Article
Clarke, K. E., Sorrell, S., Breheny, C., Jepson, R. E., Adamantos, S., Milne, E. M., & Gunn-moore, D. (2020). Dysautonomia in 53 cats and dogs: retrospective review of clinical data and outcome. Veterinary Record, https://doi.org/10.1136/vr.105258

The aim of this study was to perform a retrospective multicentre review of clinical data relating to cats and dogs diagnosed with dysautonomia and to evaluate their outcome.

ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats (2018)
Journal Article
Acierno, M. J., Brown, S., Coleman, A. E., Jepson, R. E., Papich, M., Stepien, R. L., & Syme, H. M. (2018). ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15331

An update to the 2007 American College of Veterinary Internal Medicine (ACVIM) consensus statement on the identification, evaluation, and management of systemic hypertension in dogs and cats was presented at the 2017 ACVIM Forum in National Harbor, M... Read More about ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats.

Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK (2018)
Journal Article
Stevens, K. B., O'Neill, D. G., Jepson, R. E., Holm, L. P., Walker, D. J., & Cardwell, J. M. (2018). Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK. Veterinary Record, 183(14), 448. https://doi.org/10.1136/vr.104891

Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an incre... Read More about Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK.