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The immediate effects of foot orthoses on hip and knee kinematics and muscle activity during a functional step-up task in individuals with patellofemoral pain (2014)
Journal Article
Lack, S., Barton, C., Woledge, R. C., Laupheimer, M. W., & Morrissey, D. (2014). The immediate effects of foot orthoses on hip and knee kinematics and muscle activity during a functional step-up task in individuals with patellofemoral pain. Clinical Biomechanics, 29(9), https://doi.org/10.1016/j.clinbiomech.2014.08.005

Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes (2014)
Journal Article
Fernandez-Fuente, M., Terracciano, C. M., Martin-Duque, P., Brown, S. C., Vassaux, G., & Piercy, R. J. (2014). Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes. PLoS ONE, 9(8), e105971. https://doi.org/10.1371/journal.pone.0105971

Dysfunctional skeletal muscle calcium homeostasis plays a central role in the pathophysiology of several human and animal skeletal muscle disorders, in particular, genetic disorders associated with ryanodine receptor 1 (RYR1) mutations, such as malig... Read More about Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes.

Cardiovascular changes after administration of aerosolized salbutamol in horses: five cases (2014)
Journal Article
Casoni, D., Spadavecchia, C., & Adami, C. (2014). Cardiovascular changes after administration of aerosolized salbutamol in horses: five cases. Acta Veterinaria Scandinavica, 56(49), https://doi.org/10.1186/s13028-014-0049-z

Prevention and treatment of intraoperative hypoxemia in horses is difficult and both efficacy and safety of therapeutic maneuvers have to be taken into account. Inhaled salbutamol has been suggested as treatment of hypoxia in horses during general an... Read More about Cardiovascular changes after administration of aerosolized salbutamol in horses: five cases.

Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma (2014)
Journal Article
Pinheiro, D. Y., Chang, Y. M., Bryant, H., Szladovits, B., Dalessandri, T., Davison, L. J., …Garden, O. A. (2014). Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma. PLoS ONE, 9(8), e105027. https://doi.org/10.1371/journal.pone.0105027

The cancer microenvironment plays a pivotal role in oncogenesis, containing a number of regulatory cells that attenuate the anti-neoplastic immune response. While the negative prognostic impact of regulatory T cells (Tregs) in the context of most sol... Read More about Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma.

Attitudes and Beliefs of Pig Farmers and Wild Boar Hunters Towards Reporting of African Swine Fever in Bulgaria, Germany and the Western Part of the Russian Federation (2014)
Journal Article
Vergne, T., Guinat, C., Petkova, P., Gogin, A., Kolbasov, D., Blome, S., …Pfeiffer, D. U. (2014). Attitudes and Beliefs of Pig Farmers and Wild Boar Hunters Towards Reporting of African Swine Fever in Bulgaria, Germany and the Western Part of the Russian Federation. Transboundary and Emerging Diseases, 63(2), E194-E204. https://doi.org/10.1111/tbed.12254

High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial (2014)
Journal Article
Purcell, R., Latham, S. H., Botham, K. M., Hall, W. L., & Wheeler-Jones, C. P. D. (2014). High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial. American Journal of Clinical Nutrition, 100(4), 1019-1028. https://doi.org/10.3945/ajcn.114.091223

A review of the metrics for One Health benefits: -EN- A review of the metrics for One Health benefits -FR- Examen des méthodes de mesure des bénéfices de l’approche « Une seule santé » -ES- Estudio sobre la cuantificación de los beneficios derivados de «Una sola salud» (2014)
Journal Article
HASLER, B., CORNELSEN, L., BENNANI, H., & RUSHTON, J. (2014). A review of the metrics for One Health benefits: -EN- A review of the metrics for One Health benefits -FR- Examen des méthodes de mesure des bénéfices de l’approche « Une seule santé » -ES- Estudio sobre la cuantificación de los beneficios derivados de «Una sola salud». Revue E, 33(2), 453-464. https://doi.org/10.20506/rst.33.2.2294

Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance (2014)
Journal Article
Talbot, N. A., Wheeler-Jones, C. P. D., & Cleasby, M. E. (2014). Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance. Molecular and Cellular Endocrinology, 393(1-2), 129-142. https://doi.org/10.1016/j.mce.2014.06.010

Obesity and saturated fatty acid (SFA) treatment are both associated with skeletal muscle insulin resistance (IR) and increased macrophage infiltration. However, the relative effects of SFA and unsaturated fatty acid (UFA)-activated macrophages on mu... Read More about Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance.

Comparison of air sac volume, lung volume and lung densities determined by use of computed tomography in conscious and anesthetized Humboldt penguins (Spheniscus humboldti) positioned in ventral, dorsal and right lateral recumbency (2014)
Journal Article
Nevitt, B. N., Langan, J. N., Adkesson, M. J., Mitchell, M. A., Henzler, M., & Drees, R. (2014). Comparison of air sac volume, lung volume and lung densities determined by use of computed tomography in conscious and anesthetized Humboldt penguins (Spheniscus humboldti) positioned in ventral, dorsal and right lateral recumbency. American Journal of Veterinary Research, 75(8), 739-45. https://doi.org/10.2460/ajvr.75.8.739

Herd-Level Risk Factors for the Seropositivity to Mycoplasma hyopneumoniae and the Occurrence of Enzootic Pneumonia Among Fattening Pigs in Areas of Endemic Infection and High Pig Density (2014)
Journal Article
Nathues, H., Chang, Y. M., Wieland, B., Rechter, G., Spergser, J., Rosengarten, R., …Beilage, E. G. (2014). Herd-Level Risk Factors for the Seropositivity to Mycoplasma hyopneumoniae and the Occurrence of Enzootic Pneumonia Among Fattening Pigs in Areas of Endemic Infection and High Pig Density. Transboundary and Emerging Diseases, 61(4), 316-328. https://doi.org/10.1111/tbed.12033

The aim of the present study was to identify potential risk factors for the occurrence of enzootic pneumonia (EP) in herds situated in a region of high pig density, where a majority of herds is endemically infected with Mycoplasma hyopneumoniae. Betw... Read More about Herd-Level Risk Factors for the Seropositivity to Mycoplasma hyopneumoniae and the Occurrence of Enzootic Pneumonia Among Fattening Pigs in Areas of Endemic Infection and High Pig Density.

SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion (2014)
Journal Article
Cabrera-Sharp, V., Read, J. E., Richardson, S., Kowalski, A. A., Antczak, D. F., Cartwright, J. E., …De Mestre, A. M. (2014). SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion. Endocrinology, 155(8), 3054-64. https://doi.org/10.1210/en.2013-2116

TGFβ superfamily proteins, acting via SMAD (Sma- and Mad-related protein)2/3 pathways, regulate placental function; however, the role of SMAD1/5/8 pathway in the placenta is unknown. This study investigated the functional role of bone morphogenetic p... Read More about SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion.

Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation (2014)
Journal Article
Peffers, M. J., Thorpe, C. T., Collins, J. A., Eong, R., Wei, T. K., Screen, H. R., & Clegg, P. D. (2014). Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation. Journal of Biological Chemistry, 289(37), 25867-78. https://doi.org/10.1074/jbc.M114.566554

Energy storing tendons, such as the human Achilles and equine superficial digital flexor tendon (SDFT), are highly prone to injury, the incidence of which increases with aging. The cellular and molecular mechanisms that result in increased injury in... Read More about Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation.

Development and Testing of a Field Diagnostic Assay for Peste des Petits Ruminants Virus (2014)
Journal Article
Baron, J., Fishbourne, E., Couacy-Hyman, E., Abubakar, M., Jones, B. A., Frost, L., …Baron, M. D. (2014). Development and Testing of a Field Diagnostic Assay for Peste des Petits Ruminants Virus. Transboundary and Emerging Diseases, 61(5), 390-396. https://doi.org/10.1111/tbed.12266

We have developed an immunochromatographic test for the diagnosis of peste des petits ruminants (PPR) under field conditions. The diagnostic assay has been tested in the laboratory and also under field conditions in Ivory Coast, Pakistan, Ethiopia an... Read More about Development and Testing of a Field Diagnostic Assay for Peste des Petits Ruminants Virus.

Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations (2014)
Journal Article
Soper, R. J., Oguz, C., Emery, R., Pitsillides, A. A., & Hodges, S. J. (2014). Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations. Molecular Nutrition & Food Research, 58(8), 1658-1666. https://doi.org/10.1002/mnfr.201400063

The potential benefit of vitamin K as a therapeutic in osteoporosis is controversial and the vitamin K regimen being used clinically (45 mg/day) employs doses that are many times higher than required to ensure maximal gamma‐carboxylation of the vitam... Read More about Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations.

STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression (2014)
Journal Article
Turnquist, C., Wang, Y., Severson, D. T., Zhong, S., Sun, B., Ma, J., …Lu, X. (2014). STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression. https://doi.org/10.1073/pnas.1407898111

Inflammation and loss of cell polarity play pivotal roles in neurodegeneration and cancer. A central question in both diseases is how the loss of cell polarity is sensed by cell death machinery. Here, we identify apoptosis-stimulating protein of p53... Read More about STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression.

Anatomical and biomechanical traits of broiler chickens across ontogeny. Part I. Anatomy of the musculoskeletal respiratory apparatus and changes in organ size (2014)
Journal Article
Tickle, P. G., Paxton, H. P., Rankin, J. W., Hutchinson, J. R., & Codd, J. R. (2014). Anatomical and biomechanical traits of broiler chickens across ontogeny. Part I. Anatomy of the musculoskeletal respiratory apparatus and changes in organ size. https://doi.org/10.7717/peerj.432

Genetic selection for improved meat yields, digestive efficiency and growth rates have transformed the biology of broiler chickens. Modern birds undergo a 50-fold multiplication in body mass in just six weeks, from hatching to slaughter weight. Howev... Read More about Anatomical and biomechanical traits of broiler chickens across ontogeny. Part I. Anatomy of the musculoskeletal respiratory apparatus and changes in organ size.

Anatomical and biomechanical traits of broiler chickens across ontogeny. Part II. Body segment inertial properties and muscle architecture of the pelvic limb (2014)
Journal Article
Hutchinson, J. R., Paxton, H. P., Codd, J., Rankin, J. W., & Tickle, P. (2014). Anatomical and biomechanical traits of broiler chickens across ontogeny. Part II. Body segment inertial properties and muscle architecture of the pelvic limb. https://doi.org/10.7717/peerj.473

In broiler chickens, genetic success for desired production traits is often shadowed by welfare concerns related to musculoskeletal health. Whilst these concerns are clear, a viable solution is still elusive. Part of the solution lies in knowing how... Read More about Anatomical and biomechanical traits of broiler chickens across ontogeny. Part II. Body segment inertial properties and muscle architecture of the pelvic limb.