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WSAVA Therapeutic Guidelines (2020)
Other
Steagall, P. V., Pelligand, L., Page, S. W., Bourgeois, M., Weese, S., Manigot, G., Dublin, D., Ferreira, J. P., & Guardabassi, L. (2020). WSAVA Therapeutic Guidelines. Journal of Small Animal Practice

This list of essential medicines is presented by members of the WSAVA Therapeutic Guidelines Group (TGG) following extensive internal and external peer‐review. Internal peer‐review was provided by TGG members and its subcommittees, whereas external p... Read More about WSAVA Therapeutic Guidelines.

Analysis of teaching methods in anaesthesia in the undergraduate curriculum of 4 veterinary universities (2020)
Journal Article
D'Anselme, O., Pelligand, L., Veres-Nyeki, K. O., Zaccagnini, A., & Zilberstein, L. (2020). Analysis of teaching methods in anaesthesia in the undergraduate curriculum of 4 veterinary universities. Veterinary Anaesthesia and Analgesia,

Objectives:
There are no standardized methods for teaching anaesthesia in veterinary universities. Our aims were 1) design a holistic audit tool to assess anaesthesia teaching strategies in veterinary universities; 2) to apply the tool to 4 veterina... Read More about Analysis of teaching methods in anaesthesia in the undergraduate curriculum of 4 veterinary universities.

The effects of the Spanish COVID-19 lockdown on people, their pets and the human-animal bond (2020)
Journal Article
Bowen, J., García, E., Darder, P., Argüelles, J., & Fatjó, J. (2020). The effects of the Spanish COVID-19 lockdown on people, their pets and the human-animal bond

The purpose of this study was to investigate the effects of the Spanish confinement for the control of the COVID-19 pandemic on the behavior of pet cats and dogs, and the support that pets provided to their owners. We found that the quality of life o... Read More about The effects of the Spanish COVID-19 lockdown on people, their pets and the human-animal bond.

Full‐field strain of regenerated bone tissue in a femoral fracture model (2020)
Journal Article
KARALI, A., KAO, A., MEESON, R., ROLDO, M., BLUNN, G., & TOZZI, G. (2020). Full‐field strain of regenerated bone tissue in a femoral fracture model. Journal of Microscopy, https://doi.org/10.1111/jmi.12937

The mechanical behavior of regenerated bone tissue during fracture healing is key in determining its ability to withstand physiological loads. However, the strain distribution in the newly formed tissue and how this influences the way a fracture heal... Read More about Full‐field strain of regenerated bone tissue in a femoral fracture model.

Test, test, test for COVID-19 antibodies: the importance of sensitivity, specificity and predictive powers (2020)
Journal Article
specificity and predictive powers. Public Health, Vol.185, 88-90. https://doi.org/10.1016/j.puhe.2020.06.006

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody tests of varying specificity and sensitivity are now available. For informing individuals whether they have had coronavirus disease 2019 (COVID-19), they need to be very accurate.... Read More about Test, test, test for COVID-19 antibodies: the importance of sensitivity, specificity and predictive powers.

Detection of hypoglycin A and MCPA‐carnitine in equine serum and muscle tissue: optimisation and validation of a LC‐MS based method without derivatisation (2020)
Journal Article
González Medina, S., Hyde, C., Lovera, I., & Piercy, R. J. (2020). Detection of hypoglycin A and MCPA‐carnitine in equine serum and muscle tissue: optimisation and validation of a LC‐MS based method without derivatisation. Equine Veterinary Journal, https://doi.org/10.1111/evj.13303

Measurement of hypoglycin A (HGA) and its toxic metabolite, methylenecyclopropylacetic acid (MCPA), in equine serum confirms a diagnosis of atypical myopathy (AM), a pasture‐associated toxic rhabdomyolysis with high mortality linked to the ingestion... Read More about Detection of hypoglycin A and MCPA‐carnitine in equine serum and muscle tissue: optimisation and validation of a LC‐MS based method without derivatisation.

The chemokine CXCL16 can rescue the defects in insulin signaling and sensitivity caused by palmitate in C2C12 myotubes (2020)
Journal Article
Bitsi, S. (2020). The chemokine CXCL16 can rescue the defects in insulin signaling and sensitivity caused by palmitate in C2C12 myotubes. Cytokine, 133, 155154. https://doi.org/10.1016/j.cyto.2020.155154

In obesity, macrophages infiltrate peripheral tissues and secrete pro-inflammatory cytokines that impact local insulin sensitivity. Lipopolysaccharide (LPS) and the saturated fatty acid (FA) palmitate polarise macrophages towards a pro-inflammatory p... Read More about The chemokine CXCL16 can rescue the defects in insulin signaling and sensitivity caused by palmitate in C2C12 myotubes.

Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival (2020)
Journal Article
Heeley, A., O’Neill, D., Davison, L., Church, D., Corless, E., & Brodbelt, D. (2020). Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival. Canine Medicine and Genetics, 7(1), https://doi.org/10.1186/s40575-020-00087-7

Background: Diabetes mellitus (DM) is an important endocrine disorder of dogs. The objectives of this study were to estimate prevalence and incidence of DM in dogs, and to explore risk factors for DM and the survival of DM cases in primary-care clini... Read More about Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival.

Hypertension: Why Is It Critical? (2020)
Journal Article
Geddes, R. F. (2020). Hypertension: Why Is It Critical?. Veterinary Clinics of North America: Small Animal Practice, 50, 1037-1052

Hypertension is a common problem, particularly in older cats. Hypertension secondary to a concurrent disease is the most common form of hypertension in cats, particularly in association with chronic kidney disease or hyperthyroidism. However, idiopat... Read More about Hypertension: Why Is It Critical?.

Mapping human serum–induced gene networks as a basis for the creation of biomimetic periosteum for bone repair (2020)
Journal Article
Al Hosni, R., Shah, M., Cheema, U., Roberts, H., Luyten, F., & Roberts, S. (2020). Mapping human serum–induced gene networks as a basis for the creation of biomimetic periosteum for bone repair. Cytotherapy,

The periosteum is a highly vascularised, collagen-rich tissue that plays a crucial role in directing bone repair. This is orchestrated primarily by its resident progenitor cell population. Indeed, preservation of periosteum integrity is critical for... Read More about Mapping human serum–induced gene networks as a basis for the creation of biomimetic periosteum for bone repair.

The Possibility of Zero Limb-Work Gaits in Sprawled and Parasagittal Quadrupeds: Insights from Linkages of the Industrial Revolution (2020)
Journal Article
Usherwood, J. R. (2020). The Possibility of Zero Limb-Work Gaits in Sprawled and Parasagittal Quadrupeds: Insights from Linkages of the Industrial Revolution. Integrative Organismal Biology, 2(1),

Animal legs are diverse, complex, and perform many roles. One defining requirement of legs is to facilitate terrestrial travel with some degree of economy. This could, theoretically, be achieved without loss of mechanical energy if the body could tak... Read More about The Possibility of Zero Limb-Work Gaits in Sprawled and Parasagittal Quadrupeds: Insights from Linkages of the Industrial Revolution.

A New Drug–Drug Interaction Between Hydroxychloroquine and Metformin? A Signal Detection Study (2020)
Journal Article
Montastruc, J. L., & Toutain, P. L. (2020). A New Drug–Drug Interaction Between Hydroxychloroquine and Metformin? A Signal Detection Study. Drug Safety, 43(7), 657-660. https://doi.org/10.1007/s40264-020-00955-y

Introduction
Hydroxychloroquine was recently promoted in patients infected with COVID-19 infection. A recent experimental study has suggested an increased toxicity of hydroxychloroquine in association with metformin in mice.

Objective
The presen... Read More about A New Drug–Drug Interaction Between Hydroxychloroquine and Metformin? A Signal Detection Study.

Designing antifilarial drug trials using clinical trial simulators (2020)
Journal Article
Walker, M., Hamley, J., Milton, P., Monnot, F., Pedrique, B., & Basáñez, M. (2020). Designing antifilarial drug trials using clinical trial simulators. Nature Communications, 11(1), https://doi.org/10.1038/s41467-020-16442-y

Lymphatic filariasis and onchocerciasis are neglected tropical diseases (NTDs) targeted for elimination by mass (antifilarial) drug administration. These drugs are predominantly active against the microfilarial progeny of adult worms. New drugs or co... Read More about Designing antifilarial drug trials using clinical trial simulators.

Regional Transmission and Reassortment of 2.3.4.4b Highly Pathogenic Avian Influenza (HPAI) Viruses in Bulgarian Poultry 2017/18 (2020)
Journal Article
Venkatesh, D., Brouwer, A., Goujgoulova, G., Ellis, R., Seekings, J., Brown, I., & Lewis, N. (2020). Regional Transmission and Reassortment of 2.3.4.4b Highly Pathogenic Avian Influenza (HPAI) Viruses in Bulgarian Poultry 2017/18. Viruses, 12(6), 605

Between 2017 and 2018, several farms across Bulgaria reported outbreaks of H5 highly-pathogenic avian influenza (HPAI) viruses. In this study we used genomic and traditional epidemiological analyses to trace the origin and subsequent spread of these... Read More about Regional Transmission and Reassortment of 2.3.4.4b Highly Pathogenic Avian Influenza (HPAI) Viruses in Bulgarian Poultry 2017/18.

A systematic review on integration mechanisms in human and animal health surveillance systems with a view to addressing global health security threats (2020)
Journal Article
George, J., Häsler, B., Mremi, I., Sindato, C., Mboera, L., Rweyemamu, M., & Mlangwa, J. (2020). A systematic review on integration mechanisms in human and animal health surveillance systems with a view to addressing global health security threats. One Health Outlook, 2(1),

Lymphatic filariasis and onchocerciasis are neglected tropical diseases (NTDs) targeted for elimination by mass (antifilarial) drug administration. These drugs are predominantly active against the microfilarial progeny of adult worms. New drugs or co... Read More about A systematic review on integration mechanisms in human and animal health surveillance systems with a view to addressing global health security threats.