Skip to main content

Research Repository

Advanced Search

All Outputs (402)

Owner Reported Management Of Interictal Anxiety Behaviours In Canine Epilepsy (2022)
Journal Article
Hobbs, S., Blackwell, E., Wetz, K., & Packer, R. (2022). Owner Reported Management Of Interictal Anxiety Behaviours In Canine Epilepsy. Veterinary Record, https://doi.org/10.1002/vetr.1321

Background Idiopathic epilepsy (IE) is the most common chronic neurological condition in dogs, that can be associated with inter-ictal (between seizure) anxiety (IIA). It is unclear how owners manage their pet’s IIA, including how much veterinary su... Read More about Owner Reported Management Of Interictal Anxiety Behaviours In Canine Epilepsy.

Risk factors and implications associated with renal mineralization in chronic kidney disease in cats (2022)
Journal Article
Tang, P., Jepson, R., Chang, Y., Geddes, R., Hopkinson, M., & Elliott, J. (2022). Risk factors and implications associated with renal mineralization in chronic kidney disease in cats. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16363

Background Nephrocalcinosis is a pathological feature of chronic kidney disease (CKD). Its pathophysiological implications for cats with CKD are unexplored. Objectives Identify nephrocalcinosis risk factors and evaluate its influence on CKD prog... Read More about Risk factors and implications associated with renal mineralization in chronic kidney disease in cats.

Severe thrombocytopenia due to subinvolution of placental sites in a Maltese terrier (2022)
Journal Article
Crosby, J., Plested, M., Hardas, A., & Olivares, G. (in press). Severe thrombocytopenia due to subinvolution of placental sites in a Maltese terrier. Vet Record Case Reports, https://doi.org/10.1002/vrc2.288

A 6-year 2-month, primiparous, female, entire Maltese terrier presented 4 weeks after whelping with an acute history of lethargy and vulval haemorrhage. It was found to be anaemic and severely thrombocytopenic, which raised the concern about thromboc... Read More about Severe thrombocytopenia due to subinvolution of placental sites in a Maltese terrier.

Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy (2022)
Journal Article
Riddell, D. O., Hildyard, J. C. W., Harron, R. C. M., Wells, D. J., & Piercy, R. J. (in press). Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy. Wellcome Open Research, https://doi.org/10.12688/wellcomeopenres.17398.1

Background: Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease affecting approximately 1 in 6000 male births worldwide. Due to their phenotypic similarity to human patients, large animal models are invaluable tools for pre-clinical t... Read More about Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy.

Virtual manipulation of tail postures of a gliding barn owl (Tyto alba) demonstrates drag minimisation when gliding (2022)
Journal Article
Song, J., Cheney, J., Bomphrey, R., & Usherwood, J. (2023). Virtual manipulation of tail postures of a gliding barn owl (Tyto alba) demonstrates drag minimisation when gliding. Journal of the Royal Society, Interface, https://doi.org/10.1098/rsif.2021.0710

Aerodynamic functions of the avian tail have been studied previously using observations of bird flight, physical models in wind tunnels, theoretical modelling, and flow visualization. However, none of these approaches has provided rigorous, quantitat... Read More about Virtual manipulation of tail postures of a gliding barn owl (Tyto alba) demonstrates drag minimisation when gliding.

A founder mutation in EHD1 presents with tubular proteinuria and deafness (2022)
Journal Article
Russell, C., Issler, N., Afonso, S., Ziegler, C., Weissman, . I., Dumitriu, S., …Schilling, A. (in press). A founder mutation in EHD1 presents with tubular proteinuria and deafness. Journal of the American Society of Nephrology,

Background: The endocytic reabsorption of proteins in the proximal tubule requires a complex machinery and defects can lead to tubular proteinuria. The precise mechanisms of endocytosis and processing of receptors and cargo are incompletely unders... Read More about A founder mutation in EHD1 presents with tubular proteinuria and deafness.

Trait-Based Vaccination of Individual Meerkats (Suricata suricatta) against Tuberculosis Provides Evidence to Support Targeted Disease Control (2022)
Journal Article
Patterson, S. J., Clutton-Brock, T. H., Pfeiffer, D. U., & Drewe, J. A. (2022). Trait-Based Vaccination of Individual Meerkats (Suricata suricatta) against Tuberculosis Provides Evidence to Support Targeted Disease Control. Animals, 12(2), 192. https://doi.org/10.3390/ani12020192

Individuals vary in their potential to acquire and transmit infections, but this fact is currently underexploited in disease control strategies. We trialled a trait-based vaccination strategy to reduce tuberculosis in free-living meerkats by targetin... Read More about Trait-Based Vaccination of Individual Meerkats (Suricata suricatta) against Tuberculosis Provides Evidence to Support Targeted Disease Control.

Validation of DE50-MD dogs as a model for the cognitive and biochemical defects in the brain phenotype of Duchenne muscular dystrophy (2022)
Journal Article
Crawford, A., Hildyard, J., Rushing, S., Wells, D., Diez Leon, M., & Piercy, R. (in press). Validation of DE50-MD dogs as a model for the cognitive and biochemical defects in the brain phenotype of Duchenne muscular dystrophy. eLife, https://doi.org/10.1242/dmm.049291

Duchenne muscular dystrophy (DMD), a fatal musculoskeletal disorder, is associated with neurodevelopmental problems and cognitive impairment caused by dystrophin deficiency in the brain. Dog models of DMD represent key translational tools to study... Read More about Validation of DE50-MD dogs as a model for the cognitive and biochemical defects in the brain phenotype of Duchenne muscular dystrophy.

Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care (2022)
Journal Article
Pegram, C., Craven, A., Packer, R., Jarvis, S., McGreevy, P., Warnes, C., …O'Neill, D. (in press). Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care. PLoS ONE, 17, https://doi.org/10.1371/journal.pone.0261139

Undesirable behaviours (UBs) in dogs are common and important issues with serious potential welfare consequences for both the dogs and their owners. This study aimed to investigate the usage of drug therapy for UBs in dogs and assess demographic risk... Read More about Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care.

Higher temperature extremes exacerbate negative disease effects in a social mammal (2022)
Journal Article
Paniw, M., Duncan, C., Groenewoud, F., Drewe, J., Manser, M., Ozgul, A., & Clutton-Brock, T. (2022). Higher temperature extremes exacerbate negative disease effects in a social mammal. Nature Climate Change, https://doi.org/10.1038/s41558-022-01284-x

One important but understudied way in which climate change may impact the fitness of individuals and populations is by altering the prevalence of infectious disease outbreaks. This is especially true in social species where endemic diseases are wides... Read More about Higher temperature extremes exacerbate negative disease effects in a social mammal.

Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs (2022)
Journal Article
Fentem, R., de Stefani, A., Quintana, R., Alcoverro, E., Jones, G., Amengual-Batle, P., & Goncalves, R. (2022). Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16353

Background Status epilepticus (SE) is an emergency associated with serious consequences for both patient and owner. Data regarding risk factors for short-term mortality or recurrence in dogs with SE is limited. Objective Identify risk factors associa... Read More about Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs.

Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data (2022)
Journal Article
Walker, M., Freitas, L. T., Halder, J. B., Brack, M., Keiser, J., King, C. H., …Basáñez, M. (in press). Improving anthelmintic treatment for schistosomiasis and soil-transmitted helminthiases through sharing and reuse of individual participant data. Wellcome Open Research, 7, 5. https://doi.org/10.12688/wellcomeopenres.17468.1

Response properties of optic flow neurons in the accessory optic system of hummingbirds versus zebra finches and pigeons (2022)
Journal Article
Gaede, A., Baliga, V., Smyth, G., Gutierrez-lbanez, C., Altshuler, D., & Wylie, D. (2022). Response properties of optic flow neurons in the accessory optic system of hummingbirds versus zebra finches and pigeons. Journal of Neurophysiology, 127(1), 130-144. https://doi.org/10.1152/jn.00437.2021

Optokinetic responses function to maintain retinal image stabilization by minimizing optic flow that occurs during self-motion. The hovering ability of hummingbirds is an extreme example of this behavior. Optokinetic responses are mediated by directi... Read More about Response properties of optic flow neurons in the accessory optic system of hummingbirds versus zebra finches and pigeons.