Airway delivery of both a BCG prime and adenoviral boost drives CD4 and CD8 T cells into the lung tissue parenchyma
(2020)
Journal Article
Kaveh, D. A., Garcia-Pelayo, M. C., Bull, N. C., Sanchez-Cordon, P. J., Spiropoulos, J., & Hogarth, P. J. (2020). Airway delivery of both a BCG prime and adenoviral boost drives CD4 and CD8 T cells into the lung tissue parenchyma. Scientific Reports, 10(1), 18703. https://doi.org/10.1038/s41598-020-75734-x
Abstract: Heterologous BCG prime-boost regimens represent a promising strategy for an urgently required improved tuberculosis vaccine. Identifying the mechanisms which underpin the enhanced protection induced by such strategies is one key aim which w... Read More about Airway delivery of both a BCG prime and adenoviral boost drives CD4 and CD8 T cells into the lung tissue parenchyma.