Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors (2020)
Journal Article
Bingor, A., Haham, T., Thornton, C., Stern-Bach, Y., & Yaka, R. (2020). Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors. Nature Communications, 11(1), https://doi.org/10.1038/s41467-020-17484-y

Zeta inhibitory peptide (ZIP), a PKMζ inhibitor, is widely used to interfere with the main- tenance of acquired memories. ZIP is able to erase memory even in the absence of PKMζ, via an unknown mechanism. We found that ZIP induces redistribution of t... Read More about Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors.

Evolution and epidemic spread of SARS-CoV-2 in Brazil (2020)
Journal Article
Candido, D. S., Claro, I. M., de Jesus, J. G., Souza, W. M., Moreira, F. R. R., Dellicour, S., Mellan, T. A., du Plessis, L., Pereira, R. H. M., Sales, F. C. S., Manuli, E. R., Thézé, J., Almeida, L., Menezes, M. T., Voloch, C. M., Fumagalli, M. J., Coletti, T. M., da Silva, C. A. M., Ramundo, M. S., Amorim, M. R., …Faria, N. (2020). Evolution and epidemic spread of SARS-CoV-2 in Brazil. Science, eabd2161. https://doi.org/10.1126/science.abd2161

Brazil currently has one of the fastest growing SARS-CoV-2 epidemics in the world. Owing to limited available data, assessments of the impact of non-pharmaceutical interventions (NPIs) on virus spread remain challenging. Using a mobility-driven trans... Read More about Evolution and epidemic spread of SARS-CoV-2 in Brazil.

Risk indictors in cats with preclinical hypertrophic cardiomyopathy: a prospective cohort study (2020)
Journal Article
Ironside, V. A., Tricklebank, P. R., & Boswood, A. (2020). Risk indictors in cats with preclinical hypertrophic cardiomyopathy: a prospective cohort study. Journal of Feline Medicine and Surgery, 1098612X2093865

Objectives
This study aimed to identify indicators of the risk of progression of preclinical hypertrophic cardiomyopathy (HCM).

Methods
This was a prospective cohort study following a population of cats with preclinical HCM. Cats serially underw... Read More about Risk indictors in cats with preclinical hypertrophic cardiomyopathy: a prospective cohort study.

The effect of stress fracture occurring within the first 12 months of training on subsequent race performance in Thoroughbreds in Hong Kong. (2020)
Journal Article
Johnston, A. S., Sidhu, A. B. S., Riggs, C. M., Verheyen, K. L. P., & Rosanowski, S. M. (2020). The effect of stress fracture occurring within the first 12 months of training on subsequent race performance in Thoroughbreds in Hong Kong. Equine Veterinary Journal, https://doi.org/10.1111/evj.13324

BACKGROUND

Racehorses are at an increased risk of stress fracture within the first 12 months of racing and when resuming training after a break. Research in these high-risk periods and on the effect of performance post-recovery is limited.

OBJE... Read More about The effect of stress fracture occurring within the first 12 months of training on subsequent race performance in Thoroughbreds in Hong Kong..

Risk factor analysis for “diagnosis not reached” results from bovine samples submitted to British veterinary laboratories in 2013–2017 (2020)
Journal Article
Ballesteros, C., Foddai, A., Smith, R. P., Stevens, K., & Drewe, J. A. (2020). Risk factor analysis for “diagnosis not reached” results from bovine samples submitted to British veterinary laboratories in 2013–2017. Preventive Veterinary Medicine, 182, https://doi.org/10.1016/j.prevetmed.2020.105099

Routine diagnostic data from laboratories are an important source of information for passive animal health surveillance. In Great Britain, the Veterinary Investigation Diagnosis Analysis (VIDA) database includes records of diagnostic submissions made... Read More about Risk factor analysis for “diagnosis not reached” results from bovine samples submitted to British veterinary laboratories in 2013–2017.

Emerging Roles for Neuropilin-2 in Cardiovascular Disease (2020)
Journal Article
Harman, J. L., Sayers, J., Chapman, C., & Pellet-Many, C. (2020). Emerging Roles for Neuropilin-2 in Cardiovascular Disease. International Journal of Molecular Sciences, 21(14), 5154. https://doi.org/10.3390/ijms21145154

Cardiovascular disease, the leading cause of death worldwide, is predominantly associated with atherosclerosis. Atherosclerosis is a chronic inflammatory disease characterised by the narrowing of large to medium-sized arteries due to a build-up of pl... Read More about Emerging Roles for Neuropilin-2 in Cardiovascular Disease.

Incidence and risk factors for neurological signs after attenuation of a single congenital portosystemic shunt in 50 cats. (2020)
Journal Article
Strickland, R., Tivers, M. S., Fowkes, R. C., & Lipscomb, V. J. (2020). Incidence and risk factors for neurological signs after attenuation of a single congenital portosystemic shunt in 50 cats. Veterinary Surgery, https://doi.org/10.1111/vsu.13489

OBJECTIVE

To determine the incidence, outcome, and risk factors for postattenuation neurological signs (PANS) in cats treated for single congenital portosystemic shunts (CPSS).

STUDY DESIGN

Retrospective cohort study.

ANIMALS

Cats (n =... Read More about Incidence and risk factors for neurological signs after attenuation of a single congenital portosystemic shunt in 50 cats..

Traumatic skull fractures in dogs and cats: A comparative analysis of neurological and computed tomographic features (2020)
Journal Article
Amengual‐Batle, P., José‐López, R., Durand, A., Czopowicz, M., Beltran, E., Guevar, J., Lazzerini, K., De Decker, S., Muñana, K., Early, P., Mariani, C., Olby, N., Petrovitch, N., & Gutierrez‐Quintana, R. (2020). Traumatic skull fractures in dogs and cats: A comparative analysis of neurological and computed tomographic features. Journal of Veterinary Internal Medicine,

Background

Traumatic skull fractures (TSF) are relatively frequent in dogs and cats, but little information is available regarding their clinical and imaging features.

Hypothesis/Objectives

To describe the neurological and computed tomograph... Read More about Traumatic skull fractures in dogs and cats: A comparative analysis of neurological and computed tomographic features.

Responsible antimicrobial use in critically ill adult horses (2020)
Journal Article
Dunkel, B. (2020). Responsible antimicrobial use in critically ill adult horses. Equine Veterinary Education, https://doi.org/10.1111/eve.13334

Due to increasing antimicrobial resistance, pressure on veterinarians is mounting to adhere to responsible use of antimicrobial drugs. Antimicrobials are frequently included in the treatment of systemically ill horses due to the strong likelihood of... Read More about Responsible antimicrobial use in critically ill adult horses.

Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo (2020)
Journal Article
Hildyard, J. C. W., Crawford, A. H., Rawson, F., Riddell, D. O., Harron, R. C. M., & Piercy, R. J. (2020). Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo. Wellcome Open Research, 5, 76. https://doi.org/10.12688/wellcomeopenres.15762.2

Background: The dystrophin gene has multiple isoforms: full-length dystrophin (dp427) is principally known for its expression in skeletal and cardiac muscle, but is also expressed in the brain, and several internal promoters give rise to shorter, N-t... Read More about Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo.

Incidence and risk factors for surgical glove perforation in small animal ophthalmic surgery (2020)
Journal Article
Massidda, P. A., Diaz, J., Tetas Pont, R., Grundon, R., Corletto, F., & Blacklock, B. (2020). Incidence and risk factors for surgical glove perforation in small animal ophthalmic surgery. Veterinary Ophthalmology, https://doi.org/10.1111/vop.12805

Objective: To determine the incidence of perforation of surgical gloves and identify
associated risk factors that contribute to glove perforation in small animal ophthalmic
surgery.
Study design: Observational cohort study.
Sample population: Sur... Read More about Incidence and risk factors for surgical glove perforation in small animal ophthalmic surgery.

Pilot study assessing the use of cabergoline for the treatment of cats with hypersomatotropism and diabetes mellitus (2020)
Journal Article
Scudder, C. J., Hazuchova, K., Gostelow, R., Church, D. B., Forcada, Y., Fowkes, R. C., & Niessen, S. J. M. (2020). Pilot study assessing the use of cabergoline for the treatment of cats with hypersomatotropism and diabetes mellitus. Journal of Feline Medicine and Surgery, 1098612X2093321. https://doi.org/10.1177/1098612X20933213

Abstract
Objectives
An affordable and effective treatment is needed to manage feline hypersomatotropism. The aim of this study was to assess whether treatment with oral cabergoline for 90 days in cats with hypersomatotropism and diabetes mellitus i... Read More about Pilot study assessing the use of cabergoline for the treatment of cats with hypersomatotropism and diabetes mellitus.

Hypertension, retinopathy, and acute kidney injury in dogs: A prospective study (2020)
Journal Article
Cole, L. P., Jepson, R., Dawson, C., & Humm, K. (2020). Hypertension, retinopathy, and acute kidney injury in dogs: A prospective study. Journal of Veterinary Internal Medicine,

Background

Systemic hypertension (SH) is a potential complication of acute kidney injury (AKI) in dogs.

Objective

To describe the prevalence of SH and hypertensive retinopathy in dogs with AKI, to investigate the relationship between SH and... Read More about Hypertension, retinopathy, and acute kidney injury in dogs: A prospective study.

Updates in Feline Diabetes Mellitus and Hypersomatotropism (2020)
Journal Article
Fleeman, L., & Gostelow, R. (2020). Updates in Feline Diabetes Mellitus and Hypersomatotropism. Veterinary Clinics of North America: Small Animal Practice, 50(5), 1085-1105. https://doi.org/10.1016/j.cvsm.2020.06.005

Flash glucose monitoring is a novel, non-invasive monitoring technique, which is increasingly used in the management of small animal diabetes. This chapter provides guidance on the use of flash glucose monitoring in cats and demonstrates how this tec... Read More about Updates in Feline Diabetes Mellitus and Hypersomatotropism.

Cortical Gray Matter Injury in Encephalopathy of Prematurity: Link to Neurodevelopmental Disorders (2020)
Journal Article
Fleiss, B., Gressens, P., & Stolp, H. B. (2020). Cortical Gray Matter Injury in Encephalopathy of Prematurity: Link to Neurodevelopmental Disorders. Frontiers in Neurology, 11, https://doi.org/10.3389/fneur.2020.00575

Preterm-born infants frequently suffer from an array of neurological damage, collectively termed encephalopathy of prematurity (EoP). They also have an increased risk of presenting with a neurodevelopmental disorder (e.g., autism spectrum disorder; a... Read More about Cortical Gray Matter Injury in Encephalopathy of Prematurity: Link to Neurodevelopmental Disorders.

Microporous Biodegradable Films Promote Therapeutic Angiogenesis (2020)
Journal Article
Hendow, E., Moazen, M., Iacoviello, F., Bozec, L., Pellet‐Many, C., & Day, R. (2020). Microporous Biodegradable Films Promote Therapeutic Angiogenesis. Advanced Healthcare Materials, 2000806

Peripheral arterial disease and critical limb ischemia are common symptoms of cardiovascular disease. Vascular surgery is used to create a bypass around occluded blood vessels to improve blood flow to ischemic muscle, thus avoiding the need for amput... Read More about Microporous Biodegradable Films Promote Therapeutic Angiogenesis.

Canine intrahepatic portosystemic shunt insertion into the systemic circulation is commonly through primary hepatic veins as assessed with CT angiography (2020)
Journal Article
Plested, M. J., Zwingenberger, A. L., Brockman, D. J., Hecht, S., Secrest, S., Culp, W. T. N., & Drees, R. (2020). Canine intrahepatic portosystemic shunt insertion into the systemic circulation is commonly through primary hepatic veins as assessed with CT angiography. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.12892

Congenital intrahepatic portosystemic shunts (IHPSS) in dogs are traditionally classified as right, left, or central divisional. There are few descriptive studies regarding the variation of IHPSS within these categories. This multicenter, analytical,... Read More about Canine intrahepatic portosystemic shunt insertion into the systemic circulation is commonly through primary hepatic veins as assessed with CT angiography.

Clinical management of lipomas in dogs under primary care in the UK (2020)
Journal Article
Pegram, C. L., Rutherford, L., Corah, C., Church, D. B., Brodbelt, D. C., & O'Neill, D. G. (2020). Clinical management of lipomas in dogs under primary care in the UK. Veterinary Record, vetrec-2019

Lipomas are relatively common and biologically benign masses of mesenchymal origin consisting of adipocytes. This study reports benchmark data on the clinical management and outcomes of lipomas in dogs under UK primary veterinary care. The study used... Read More about Clinical management of lipomas in dogs under primary care in the UK.

Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis. (2020)
Journal Article
Pastor-Fernández, I., Sungwon, K., Marugán-Hernández, V., Soutter, F., Tomley, F., & Blake, D. (2020). Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis. Parasites and Vectors,

Poultry coccidiosis is a parasitic enteric disease with a highly negative impact on chicken production. In-feed chemoprophylaxis remains the primary method of control, but the increasing ineffectiveness of anticoccidial drugs, and potential future re... Read More about Vaccination with transgenic Eimeria tenella expressing Eimeria maxima AMA1 and IMP1 confers partial protection against high level E. maxima challenge in a broiler model of coccidiosis..

Patterns of Avian Influenza A (H5) and A (H9) virus infection in backyard, commercial broiler and layer chicken farms in Bangladesh (2020)
Journal Article
Gupta, S. D., Hoque, M. A., Fournié, G., & Henning, J. (2020). Patterns of Avian Influenza A (H5) and A (H9) virus infection in backyard, commercial broiler and layer chicken farms in Bangladesh. Transboundary and Emerging Diseases, https://doi.org/10.1111/tbed.13657

In order to control Highly Pathogenic Avian Influenza (HPAI) H5N1 and Low Pathogenic Avian Influenza (LPAI) H9N2 virus spread in endemically infected countries, a detailed understanding of infection patterns is required. We conducted cross‐sectional... Read More about Patterns of Avian Influenza A (H5) and A (H9) virus infection in backyard, commercial broiler and layer chicken farms in Bangladesh.