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Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set (2017)
Journal Article
Damas, J., O'Connor, R., Farré, M., Lenis, V. P. E., Martell, H. J., Mandawala, A., …Larkin, D. M. (2017). Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set. Genome Research, 27, 697-708. https://doi.org/10.1101/gr.213660.116

Most recent initiatives to sequence and assemble new species’ genomes de novo fail to achieve the ultimate endpoint to produce contigs, each representing one whole chromosome. Even the best-assembled genomes (using contemporary technologies) consist... Read More about Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set.

Training Future Actors in the Food System: A new collaborative cross-institutional, interdisciplinary training programme for students (2017)
Journal Article
Reed, K., Reed, K., Collier, R., White, R., Wells, R., Ingram, J., …Sykes, R. (in press). Training Future Actors in the Food System: A new collaborative cross-institutional, interdisciplinary training programme for students. Exchange, 4(2), 201-218. https://doi.org/10.31273/eirj.v4i2.161

There is an urgent need to train a cohort of professionals who can address and resolve the increasing number of fundamental failings in the global food system. The solutions to these systemic failings go far beyond the production of food, and are emb... Read More about Training Future Actors in the Food System: A new collaborative cross-institutional, interdisciplinary training programme for students.

Natriuretic peptide activation of extracellular regulated kinase 1/2 (ERK1/2) pathway by particulate guanylyl cyclases in GH3 somatolactotropes (2017)
Journal Article
Jonas, K. C., Melrose, T., Thompson, I. R., Baxter, G. F., Lipscomb, V. J., Niessen, S. J. M., …Fowkes, R. C. (2017). Natriuretic peptide activation of extracellular regulated kinase 1/2 (ERK1/2) pathway by particulate guanylyl cyclases in GH3 somatolactotropes. Cell and Tissue Research, 369(3), 567-578. https://doi.org/10.1007/s00441-017-2624-x

The natriuretic peptides, Atrial-, B-type and C-type natriuretric peptides (ANP, BNP, CNP), are regulators of many endocrine tissues and exert their effects predominantly through the activation of their specific guanylyl cyclase receptors (GC-A and G... Read More about Natriuretic peptide activation of extracellular regulated kinase 1/2 (ERK1/2) pathway by particulate guanylyl cyclases in GH3 somatolactotropes.

Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats (2017)
Journal Article
Doodnaught, G. M., Monteiro, B. P., Benito, J., Edge, D., Beaudry, F., Pelligand, L., & Steagall, P. (2017). Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats. PLoS ONE, 12(4), w0176443. https://doi.org/10.1371/journal.pone.0176443

The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in cats.

Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner (2017)
Journal Article
Rhodin, M., Egenvall, A., Haubro Andersen, P., & Pfau, T. (2017). Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner. PLoS ONE, 12(4), e0176253. https://doi.org/10.1371/journal.pone.0176253

Recent studies evaluating horses in training and considered free from lameness by their owners have identified a large proportion of horses with motion asymmetries. However the prevalence, type and magnitude of asymmetries when trotting in a straight... Read More about Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner.

Terrestrial capture of prey by the reedfish, a model species for stem tetrapods (2017)
Journal Article
Van Wassenbergh, S., Bonte, C., & Michel, K. B. (2017). Terrestrial capture of prey by the reedfish, a model species for stem tetrapods. Ecology and Evolution, 7(11), 3856-3860. https://doi.org/10.1002/ece3.2694

Due to morphological resemblance, polypterid fishes are used as extant analogues of Late Devonian lobe‐finned sarcopterygians to identify the features that allowed the evolution of a terrestrial lifestyle in early tetrapods. Previous studies using po... Read More about Terrestrial capture of prey by the reedfish, a model species for stem tetrapods.

Randomised positive control trial of NSAID and antimicrobial treatment for calf fever caused by pneumonia (2017)
Journal Article
Mahendran, S. A., Booth, R. E., Burge, M., & Bell, N. J. (2017). Randomised positive control trial of NSAID and antimicrobial treatment for calf fever caused by pneumonia. Veterinary Record, 181(2), https://doi.org/10.1136/vr.104057

One hundred and fifty-four preweaning calves were followed between May and October 2015. Calves were fitted with continuous monitoring temperature probes (TempVerified FeverTag), programmed so a flashing light emitting diode (LED) light was triggered... Read More about Randomised positive control trial of NSAID and antimicrobial treatment for calf fever caused by pneumonia.

Spinal Arachnoid Diverticula: Outcome in 96 Medically or Surgically Treated Dogs (2017)
Journal Article
Mauler, D. A., De Decker, S., De Risio, L., Volk, H. A., Dennis, R., Gielen, I., …Van Ham, L. (2017). Spinal Arachnoid Diverticula: Outcome in 96 Medically or Surgically Treated Dogs. Journal of Veterinary Internal Medicine, 31, 849-853. https://doi.org/10.1111/jvim.14714

Fifty dogs were managed medically and 46 dogs were treated surgically. Dogs that underwent surgery were significantly younger than dogs that received medical management. No other variables, related to clinical presentation, were significantly differe... Read More about Spinal Arachnoid Diverticula: Outcome in 96 Medically or Surgically Treated Dogs.

The genomes and history of domestic animals (2017)
Journal Article
Larkin, D. M., & Yudin, N. S. (2017). The genomes and history of domestic animals. Molecular Genetics, Microbiology and Virology, 31(4), 197-202. https://doi.org/10.3103/S0891416816040054

This paper reviews how mammalian genomes are utilized in modern genetics for the detection of genes and polymorphisms (mutations) within domesticated animal (mostly livestock) genomes that are related to traits of economic importance to humans. Examp... Read More about The genomes and history of domestic animals.

Inference of the infection status of individuals using longitudinal testing data from cryptic populations: Towards a probabilistic approach to diagnosis (2017)
Journal Article
Buzdugan, S. N., Vergne, T., Grosbois, V., Delahay, R. J., & Drewe, J. A. (2017). Inference of the infection status of individuals using longitudinal testing data from cryptic populations: Towards a probabilistic approach to diagnosis. https://doi.org/10.1038/s41598-017-00806-4

Effective control of many diseases requires the accurate detection of infected individuals. Confidently ascertaining whether an individual is infected can be challenging when diagnostic tests are imperfect and when some individuals go for long period... Read More about Inference of the infection status of individuals using longitudinal testing data from cryptic populations: Towards a probabilistic approach to diagnosis.

RNA-binding proteins in human oogenesis: Balancing differentiation and self-renewal in the female fetal germline (2017)
Journal Article
Rosario, R., Childs, A. J., & Anderson, R. A. (2017). RNA-binding proteins in human oogenesis: Balancing differentiation and self-renewal in the female fetal germline. Stem Cell Research, 21, 193-201. https://doi.org/10.1016/j.scr.2017.04.008

Primordial germ cells undergo three significant processes on their path to becoming primary oocytes: the initiation of meiosis, the formation and breakdown of germ cell nests, and the assembly of single oocytes into primordial follicles. However at t... Read More about RNA-binding proteins in human oogenesis: Balancing differentiation and self-renewal in the female fetal germline.

Investigation looking at the repeatability of 20 Society of Master Saddlers (SMS) qualified saddle fitters’ observations during static saddle fit (2017)
Journal Article
Guire, R., Weller, R., Fisher, M., & Beavis, J. (2017). Investigation looking at the repeatability of 20 Society of Master Saddlers (SMS) qualified saddle fitters’ observations during static saddle fit. Journal of Equine Veterinary Science, 56, 1-5. https://doi.org/10.1016/j.jevs.2017.04.001

Saddle fit is widely considered to be a crucial factor for the health and performance of riding horses; however, there have been no studies looking at the agreement between professionals who fit and assess saddles. The aim of the study was to determi... Read More about Investigation looking at the repeatability of 20 Society of Master Saddlers (SMS) qualified saddle fitters’ observations during static saddle fit.