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Spherocytosis as an indicator of fragmentation injury in dogs with splenic torsion. (2024)
Journal Article
Beeston, D., Szladovits, B., & Cortellini, S. (in press). Spherocytosis as an indicator of fragmentation injury in dogs with splenic torsion. Journal of the American Veterinary Medical Association, https://doi.org/10.2460/javma.24.03.0148

Abstract
Objective
To describe the presentation, diagnosis and treatment of four cases of splenic torsion with associated spherocytosis.

Animals
Four client-owned dogs with spherocytosis and splenic torsion.

Case Presentation
Each dog prese... Read More about Spherocytosis as an indicator of fragmentation injury in dogs with splenic torsion..

Defining sepsis in small animals (2024)
Journal Article
Dvm, S. C., Declue Dvm, A. E., Dvm, M. G., Goggs Bvsc, R., Dvm, K. H., Menard, J. M., …Dvm, G. S. (2024). Defining sepsis in small animals. Journal of Veterinary Emergency and Critical Care, https://doi.org/10.1111/vec.13359

Objective: To discuss the definitions of sepsis in human and veterinary medicine. Design: International, multicenter position statement on the need for consensus definitions of sepsis in veterinary medicine. Setting: Veterinary private practice and u... Read More about Defining sepsis in small animals.

PROSPECTIVE EVALUATION OF PLATELET FUNCTION AND FIBRINOLYSIS IN 20 DOGS WITH TRAUMA (2023)
Journal Article
Cortellini, S., Chan, D., McBride, D., & Birkbeck, R. (in press). PROSPECTIVE EVALUATION OF PLATELET FUNCTION AND FIBRINOLYSIS IN 20 DOGS WITH TRAUMA. Journal of Veterinary Emergency and Critical Care, https://doi.org/10.1111/vec.13356

Objectives: To determine platelet function and fibrinolysis in dogs following trauma using multiple electrical impedance aggregometry and a modified thromboelastographic technique. To determine if the severity of trauma, as assessed by the Animal Tr... Read More about PROSPECTIVE EVALUATION OF PLATELET FUNCTION AND FIBRINOLYSIS IN 20 DOGS WITH TRAUMA.

Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM (2023)
Journal Article
Beeston, D., & Cortellini, S. (in press). Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM. Veterinary Record,

This case report details the clinical investigation of an 11-month intact male Cockapoo who presented with acute left forebrain signs associated with suspected intra-cranial haemorrhage due to Angiostrongylus vasorum.

Initial investigations faile... Read More about Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM.

Medical management of metallic sharp-pointed straight gastrointestinal foreign bodies in dogs and cats: 18 cases (2023)
Journal Article
Crinó, C., Humm, K., & Cortellini, S. (2023). Medical management of metallic sharp-pointed straight gastrointestinal foreign bodies in dogs and cats: 18 cases. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13606

OBJECTIVE – To describe the medical treatment of gastrointestinal metallic sharp-pointed straight foreign bodies (FBs) in dogs and cats
MATERIALS AND METHODS – Clinical records of dogs and cats presented to a university teaching hospital between 200... Read More about Medical management of metallic sharp-pointed straight gastrointestinal foreign bodies in dogs and cats: 18 cases.

Successful management of fipronil toxicosis in two pet rabbits (2022)
Journal Article
D'Ovidio, D., & Cortellini, S. (2022). Successful management of fipronil toxicosis in two pet rabbits. Open Veterinary Journal, 12(4), 508-510. https://doi.org/10.5455/OVJ.2022.v12.i4.13

Background: Antiparasitic drug toxicosis is commonly described in dogs and cats, but reports on the management of antiparasitic drug toxicities in pet rabbits are scarce. Here, we describe the successful clinical management of two pet rabbits with fi... Read More about Successful management of fipronil toxicosis in two pet rabbits.

Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019) (2022)
Journal Article
Beeston, D., Jepson, R., & Cortellini, S. (2022). Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019). Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13530

Title: Evaluation of presentation, treatment and outcome in hypertensive emergency in dogs and cats: 15 cases (2003-2019).
Introduction: Hypertensive emergency (HE) is well-recognised in human medicine, yet there is limited veterinary evidence. This... Read More about Evaluation Of Presentation Treatment And Outcome In Hypertensive Emergency in dogs and cats: 15 cases (2003-2019).

The use of haemodialysis for the treatment of phenobarbitone intoxication 30 hours after ingestion (2022)
Journal Article
Cortellini, S., Greensmith, T., Cole, L., & Trinder, R. (2022). The use of haemodialysis for the treatment of phenobarbitone intoxication 30 hours after ingestion. Veterinary Record, https://doi.org/10.1002/vrc2.395

An 18-month-old male neutered Cocker Spaniel presented with a comatose mentation to his primary care veterinarian following the presumed ingestion of 216mg/kg of phenobarbitone two hours prior. Following a failure to improve with intravenous fluids,... Read More about The use of haemodialysis for the treatment of phenobarbitone intoxication 30 hours after ingestion.

2022 Update of the Consensus on the Rational Use of Antithrombotics and Thrombolytics in Veterinary Critical Care (CURATIVE) Domain 1- Defining populations at risk (2022)
Journal Article
Chan, D., deLaforcade, A., Bacek, L., Boyd, C., Blais, M., Brainard, B., …Sharp, C. (2022). 2022 Update of the Consensus on the Rational Use of Antithrombotics and Thrombolytics in Veterinary Critical Care (CURATIVE) Domain 1- Defining populations at risk. Journal of Veterinary Emergency and Critical Care,

Abstract
Objectives: To expand the number of conditions and interventions explored for the associations with thrombosis in the veterinary literature, and to provide the basis for prescribing recommendations.

Design: A population exposure compari... Read More about 2022 Update of the Consensus on the Rational Use of Antithrombotics and Thrombolytics in Veterinary Critical Care (CURATIVE) Domain 1- Defining populations at risk.

Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass (2022)
Journal Article
Starybrat, D., Jepson, R., Bristow, P., Peterson, S., Yerramilli, M., Yerramilli, M., …Cortellini, S. (in press). Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass. Journal of Veterinary Emergency and Critical Care,

Objective - Assess the occurrence of acute kidney injury (AKI) in dogs undergoing cardiac surgery under cardiopulmonary bypass (CPB) and explore associations between traditional and novel serum and urinary biomarkers.
Design – Prospective cohort st... Read More about Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass.

Respiratory complications in dogs with tetanus: A retrospective study of 53 cases (2021)
Journal Article
Guedra, M., Cortellini, S., & Humm, K. (2021). Respiratory complications in dogs with tetanus: A retrospective study of 53 cases. Journal not listed, 62(11), 1202-1206

Tetanus can lead to respiratory complications, and the outcome of dogs affected by this disease is still largely unknown. This retrospective study aimed to evaluate the frequency and outcome of 53 dogs with tetanus and respiratory complications betwe... Read More about Respiratory complications in dogs with tetanus: A retrospective study of 53 cases.

Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs (2021)
Journal Article
Vegas Cómitre, M., Cortellini, S., Devreese, M., Roques, B., Bousquet-Melou, A., Toutain, P., & Pelligand, L. (2021). Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs. Journal of Veterinary Medicine, https://doi.org/10.3389/fvets.2021.770202

Background – Data regarding antimicrobial pharmacokinetics (PK) in critically ill dogs is lacking and likely differs from healthy dogs.

Hypothesis/Objectives —To describe a population PK model for intravenous amoxicillin clavulanic acid (AMC) in... Read More about Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs.

A review of hyperfibrinolysis in cats and dogs (2019)
Journal Article
Birkbeck, R. N., Cortellini, S., & Humm, K. R. (2019). A review of hyperfibrinolysis in cats and dogs. Journal of Small Animal Practice, 60(11), 641-655. https://doi.org/10.1111/jsap.13068

The fibrinolytic system is activated concurrently with coagulation; it regulates haemostasis and prevents thrombosis by restricting clot formation to the area of vascular injury and dismantling the clot as healing occurs. Dysregulation of the fibrino... Read More about A review of hyperfibrinolysis in cats and dogs.

Description of the use of plasma exchange in dogs with Cutaneous and Renal Glomerular Vasculopathy (2018)
Journal Article
Skulberg, R., Cortellini, S., Chan, D. L., Giacomo, S., & Jepson, R. E. (2018). Description of the use of plasma exchange in dogs with Cutaneous and Renal Glomerular Vasculopathy. Frontiers in Veterinary Science, 5(161), https://doi.org/10.3389/fvets.2018.00161

Cutaneous and renal glomerular vasculopathy (CRGV) is a rare disease affecting dogs, with a recent apparent increase in prevalence since 2012 in the UK. This disease is characterized by a vasculopathy affecting small vessels of the kidney and skin, l... Read More about Description of the use of plasma exchange in dogs with Cutaneous and Renal Glomerular Vasculopathy.